TLR10 (NM_030956) Human Untagged Clone

CAT#: SC125241

TLR10 (untagged)-Human toll-like receptor 10 (TLR10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TLR10
• Synonyms: CD290
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125241 sequence for NM_030956 edited (data generated by NextGen Sequencing)
  ATGAGACTCATCAGAAACATTTACATATTTTGTAGTATTGTTATGACAGCAGAGGGTGAT
  GCTCCAGAGCTGCCAGAAGAAAGGGAACTGATGACCAACTGCTCCAACATGTCTCTAAGA
  AAGGTTCCCGCAGACTTGACCCCAGCCACAACGACACTGGATTTATCCTATAACCTCCTT
  TTTCAACTCCAGAGTTCAGATTTTCATTCTGTCTCCAAACTGAGAGTTTTGATTCTATGC
  CATAACAGAATTCAACAGCTGGATCTCAAAACCTTTGAATTCAACAAGGAGTTAAGATAT
  TTAGATTTGTCTAATAACAGACTGAAGAGTGTAACTTGGTATTTACTGGCAGGTCTCAGG
  TATTTAGATCTTTCTTTTAATGACTTTGACACCATGCCTATCTGTGAGGAAGCTGGCAAC
  ATGTCACACCTGGAAATCCTAGGTTTGAGTGGGGCAAAAATACAAAAATCAGATTTCCAG
  AAAATTGCTCATCTGCATCTAAATACTGTCTTCTTAGGATTCAGAACTCTTCCTCATTAT
  GAAGAAGGTAGCCTGCCCATCTTAAACACAACAAAACTGCACATTGTTTTACCAATGGAC
  ACAAATTTCTGGGTTCTTTTGCGTGATGGAATCAAGACTTCAAAAATATTAGAAATGACA
  AATATAGATGGCAAAAGCCAATTTGTAAGTTATGAAATGCAACGAAATCTTAGTTTAGAA
  CATGCTAAGACATCGGTTCTATTGCTTAATAAAGTTGATTTACTCTGGGACGACCTTTTC
  CTTATCTTACAATTTGTTTGGCATACATCAGTGGAACACTTTCAGATCCGAAATGTGACT
  TTTGGTGGTAAGGCTTATCTTGACCACAATTCATTTGACTACTCAAATACTGTAATGAGA
  ACTATAAAATTGGAGCATGTACATTTCAGAGTGTTTTACATTCAACAGGATAAAATCTAT
  TTGCTTTTGACCAAAATGGACATAGAAAACCTGACAATATCAAATGCACAAATGCCACAC
  ATGCTTTTCCCTAATTATCCTACGAAATTCCAATATTTAAATTTTGCCAATAATATCTTA
  ACAGACGAGTTGTTTAAAAGAACTCTCCAACTGCCTCACTTGAAAACTCTCATTTTGAAT
  GGCAATAAACTGGAGACACTTTCTTTAGTAAGTTGCTTTGCTAACAACACACCCTTGGAA
  CACTTGGATCTGAGTCAAAATCTATTACAACATAAAAATGATGAAAATTGCTCATGGCCA
  GAAACTGTGGTCAATATGAATCTGTCATACAATAAATTGTCTGATTCTGTCTTCAGGTGC
  TTGCCCAAAAGTATTCAAATACTTGACCTAAATAATAACCAAATCCAAACTGTACCTAAA
  GAGACTATTCATCTGATGGCCTTACGAGAACTAAATATTGCATTTAATTTTCTAACTGAT
  CTCCCTGGATGCAGTCATTTCAGTAGACTTTCAGTTCTGAACATTGAAATGAACTTCATT
  CTCAGCCCATCTCTGGATTTTGTTCAGAGCTGCCAGGAAGTTAAAACTCTAAATGCGGGA
  AGAAATCCATTCCGGTGTACCTGTGAATTAAAAAATTTCATTCAGCTTGAAACATATTCA
  GAGGTCATGATGGTTGGATGGTCAGATTCATACACCTGTGAATACCCTTTAAACCTAAGG
  GGAACTAGGTTAAAAGACGTTCATCTCCACGAATTATCTTGCAACACAGCTCTGTTGATT
  GTCACCATTGTGGTTATTATGCTAGTTCTGGGGTTGGCTGTGGCCTTCTGCTGTCTCCAC
  TTTGATCTGCCCTGGTATCTCAGGATGCTAGGTCAATGCACACAAACATGGCACAGGGTT
  AGGAAAACAACCCAAGAACAACTCAAGAGAAATGTCCGATTCCACGCATTTATTTCATAC
  AGTGAACATGATTCTCTGTGGGTGAAGAATGAATTGATCCCCAATCTAGAGAAGGAAGAT
  GGTTCTATCTTGATTTGCCTTTATGAAAGCTACTTTGACCCTGGCAAAAGCATTAGTGAA
  AATATTGTAAGCTTCATTGAGAAAAGCTATAAGTCCATCTTTGTTTTGTCTCCCAACTTT
  GTCCAGAATGAGTGGTGCCATTATGAATTCTACTTTGCCCACCACAATCTCTTCCATGAA
  AATTCTGATCACATAATTCTTATCTTACTGGAACCCATTCCATTCTATTGCATTCCCACC
  AGGTATCATAAACTGAAAGCTCTCCTGGAAAAAAAAGCATACTTGGAATGGCCCAAGGAT
  AGGCGTAAATGTGGGCTTTTCTGGGCAAACCTTCGAGCTGCTGTTAATGTTAATGTATTA
  GCCACCAGAGAAATGTATGAACTGCAGACATTCACAGAGTTAAATGAAGAGTCTCGAGGT
  TCTACAATCTCTCTGATGAGAACAGACTGTCTATAA
  
  Clone variation with respect to NM_030956.3
  721 a=>c;1032 g=>t;1105 a=>c;2172 t=>c;2323 a=>g;2427 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030956 unedited
  AGGGAAGTTGNNCNATTGGTAGCCTTTTGAAAACGCCTCACTATAGGGCGGCCGCGAATT
  NNNNCGAGAACGAATCATCCACGCACCTGCAGCTCTGCTGAGAGAGTGCAAGCCGTGGGG
  GTTTTGAGCTCATCTTCATCATTCATATGAGGAAATAAGTGGTAGAATCCTTGGAAATAC
  AATGAGACTCATCAGAAACATTTACATATTTTGTAGTATTGTTATGACAGCAGAGGGTGA
  TGCTCCAGAGCTGCCAGAAGAAAGGGAACTGATGACCAACTGCTCCAACATGTCTCTAAG
  AAAGGTTCCCGCAGACTTGACCCCAGCCACAACGACACTGGATTTATCCTATAACCTCCT
  TTTTCAACTCCAGAGTTCAGATTTTCATTCTGTCTCCAAACTGAGAGTTTTGATTCTATG
  CCATAACAGAATTCAACAGCTGGATCTCAAAACCTTTGAATTCAACAAGGAGTTAAGATA
  TTTAGATTTGTCTAATAACAGACTGAAGAGTGTAACTTGGTATTTACTGGCAGGTCTCAG
  GTATTTAGATCTTTCTTTTAATGACTTTGACACCATGCCTATCTGTGAGGAAGCTGGCAA
  CATGTCACACCTGGAAATCCTAGGTTTGAGTGGGGCAAAAATACAAAAATCAGATTTCCA
  GAAAATTGCTCATCTGCATCTAAATACTGTCTTCTTAGGATTCAGAACTCTTCCTCATTA
  TGAAGAAGGTAGCCTGGCCATCTTANACACAACAAAACTGCACATTGGGTTTACCATGGA
  CACAAATTTCTGGGGTCTTTNGCGTGATGGAATCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_030956 unedited
  CAGCCAGGAGAGGCACTGNNAAANCNTNAAGGGATGCCACCCGGGATCTGTTCAAGAAAC
  AGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTGAGAT
  GGAGTCTCGCTCTGTCACCAGGCTGGAGTGCANTNNCTCNNTCTCAACTCACTGCAACTG
  CCACCTCCCAAGTTCAAGCGATTCTCCTGCCTCAACCGTCCAAGTAGCTGGGACTACAGG
  CGAGCACCGTCACTCCCCGCTAACTCTTGGATTTTTAGTAAAAACAAGGTTACACCATGC
  TGGCCAGGATGGTATACATCTCTTGACCTCAAGGTTAACCCCCCTTGGCCTCCAACAGTG
  TTGGGATTACAAAATTGAGCCACTGCACCTGGACACACCTTTCATGATAATAAACAATCA
  TGGGATGAACACCTTCTTCCATAAGCCCTAATAAACCTAGGAAGGTGTTTCTATTTGATA
  CATTCTTAAAAATCCTTCTATGAACTGATATGAACGGAATAACCCCTTTCAATTATAATA
  AATATGTGTCAAATTGGCATAATAAACGTTGTATCAAAGAACATCCCAACTAGCATTGTG
  AGTCCCATCTTTCCAAAGGCTGGGGGCATTTTTAAACAGACTGGTCCTATCTAACATCAT
  GAAAAACTACAGAATGTTTATTATCATTGTGAAATCTGGATACAATAAATATTCTGCTGT
  CTAAACTAACTATAACAGACACTCCAAGTTTGCCAAAAGACCAATAACCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030956
• ORF Size: 2436 bp
• Insert Size: 3600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_030956.2, NP_112218.2
• RefSeq Size: 3594
• RefSeq ORF: 2436
• Locus ID: 81793
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein (isoform a).