KDM1A (NM_015013) Human Untagged Clone

CAT#: SC125274

KDM1A (untagged)-Human lysine (K)-specific demethylase 1A (KDM1A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM1A
• Synonyms: AOF2; BHC110; CPRF; KDM1; LSD1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125274 sequence for NM_015013 edited (data generated by NextGen Sequencing)
  ATGTTATCTGGGAAGAAGGCGGCAGCCGCGGCGGCGGCGGCTGCAGCGGCAGCAACCGGG
  ACGGAGGCTGGCCCTGGGACAGCAGGCGGCTCCGAGAACGGGTCTGAGGTGGCCGCGCAG
  CCCGCGGGCCTGTCGGGCCCAGCCGAGGTCGGGCCGGGGGCGGTGGGGGAGCGCACACCC
  CGCAAGAAAGAGCCTCCGCGGGCCTCGCCCCCCGGGGGCCTGGCGGAACCGCCGGGGTCC
  GCAGGGCCTCAGGCCGGCCCTACTGTCGTGCCTGGGTCTGCGACCCCCATGGAAACTGGA
  ATAGCAGAGACTCCGGAGGGGCGTCGGACCAGCCGGCGCAAGCGGGCGAAGGTAGAGTAC
  AGAGAGATGGATGAAAGCTTGGCCAACCTCTCAGAAGATGAGTATTATTCAGAAGAAGAG
  AGAAATGCCAAAGCAGAGAAGGAAAAGAAGCTTCCCCCACCACCCCCTCAAGCCCCACCT
  GAGGAAGAAAATGAAAGTGAGCCTGAAGAACCATCGGGTGTGGAGGGCGCAGCTTTCCAG
  AGCCGACTTCCTCATGACCGGATGACTTCTCAAGAAGCAGCCTGTTTTCCAGATATTATC
  AGTGGACCACAACAGACCCAGAAGGTTTTTCTTTTCATTAGAAACCGCACACTGCAGTTG
  TGGTTGGATAATCCAAAGATTCAGCTGACATTTGAGGCTACTCTCCAACAATTAGAAGCA
  CCTTATAACAGTGATACTGTGCTTGTCCACCGAGTTCACAGTTATTTAGAGCGTCATGGT
  CTTATCAACTTCGGCATCTATAAGAGGATAAAACCCCTACCAACTAAAAAGACAGGAAAG
  GTAATTATTATAGGCTCTGGGGTCTCAGGCTTGGCAGCAGCTCGACAGTTACAAAGTTTT
  GGAATGGATGTCACACTTTTGGAAGCCAGGGATCGTGTGGGTGGACGAGTTGCCACATTT
  CGCAAAGGAAACTATGTAGCTGATCTTGGAGCCATGGTGGTAACAGGTCTTGGAGGGAAT
  CCTATGGCTGTGGTCAGCAAACAAGTAAATATGGAACTGGCCAAGATCAAGCAAAAATGC
  CCACTTTATGAAGCCAACGGACAAGCTGTTCCTAAAGAGAAAGATGAAATGGTAGAGCAA
  GAGTTTAACCGGTTGCTAGAAGCTACATCTTACCTTAGTCATCAACTAGACTTCAATGTC
  CTCAATAATAAGCCTGTGTCCCTTGGCCAGGCATTGGAAGTTGTCATTCAGTTACAAGAG
  AAGCATGTCAAAGATGAGCAGATTGAACATTGGAAGAAGATAGTGAAAACTCAGGAAGAA
  TTGAAAGAACTTCTTAATAAGATGGTAAATTTGAAAGAGAAAATTAAAGAACTCCATCAG
  CAATACAAAGAAGCATCTGAAGTAAAGCCACCCAGAGATATTACTGCCGAGTTCTTAGTG
  AAAAGCAAACACAGGGATCTGACCGCCCTATGCAAGGAATATGATGAATTAGCTGAAACA
  CAAGGAAAGCTAGAAGAAAAACTTCAGGAGTTGGAAGCGAATCCCCCAAGTGATGTATAT
  CTCTCATCAAGAGACAGACAAATACTTGATTGGCATTTTGCAAATCTTGAATTTGCTAAT
  GCCACACCTCTCTCAACTCTCTCCCTTAAGCACTGGGATCAGGATGATGACTTTGAGTTC
  ACTGGCAGCCACCTGACAGTAAGGAATGGCTACTCGTGTGTGCCTGTGGCTTTAGCAGAA
  GGCCTAGACATTAAACTGAATACAGCAGTGCGACAGGTTCGCTACACGGCTTCAGGATGT
  GAAGTGATAGCTGTGAATACCCGCTCCACGAGTCAAACCTTTATTTATAAATGCGACGCA
  GTTCTCTGTACCCTTCCCCTGGGTGTGCTGAAGCAGCAGCCACCAGCCGTTCAGTTTGTG
  CCACCTCTCCCTGAGTGGAAAACATCTGCAGTCCAAAGGATGGGATTTGGCAACCTTAAC
  AAGGTGGTGTTGTGTTTTGATCGGGTGTTCTGGGATCCAAGTGTCAATTTGTTCGGGCAT
  GTTGGCAGTACGACTGCCAGCAGGGGTGAGCTCTTCCTCTTCTGGAACCTCTATAAAGCT
  CCAATACTGTTGGCACTAGTGGCAGGAGAAGCTGCTGGTATCATGGAAAACATAAGTGAC
  GATGTGATTGTTGGCCGATGCCTGGCCATTCTCAAAGGGATTTTTGGTAGCAGTGCAGTA
  CCTCAGCCCAAAGAAACTGTGGTGTCTCGTTGGCGTGCTGATCCCTGGGCTCGGGGCTCT
  TATTCCTATGTTGCTGCAGGATCATCTGGAAATGACTATGATTTAATGGCTCAGCCAATC
  ACTCCTGGCCCCTCGATTCCAGGTGCCCCACAGCCGATTCCACGACTCTTCTTTGCGGGA
  GAACATACGATCCGTAACTACCCAGCCACAGTGCATGGTGCTCTGCTGAGTGGGCTGCGA
  GAAGCGGGAAGAATTGCAGACCAGTTTTTGGGGGCCATGTATACGCTGCCTCGCCAGGCC
  ACACCAGGTGTTCCTGCACAGCAGTCCCCAAGCATGTGA
  
  Clone variation with respect to NM_015013.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015013 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGGAGCGCGCTTGGCGCG
  TGCGTACGCGACGGCGGTTGGCGGCGCGCGGGCAGCGTGAAGCGAGGCGAGGCAAGGCTT
  TTCGGACCCACGGAGCGACAGAGCGAGCGGCCCCTACGGCCGTCGGCGGCCCGGCGGCCC
  GAGATGTTATCTGGGAAGAAGGCGGCAGCCGCGGCGGCGGCGGCTGCAGCGGCAGCAACC
  GGGACGGAGGCTGGCCCTGGGACAGCAGGCGGCTCCGAGAACGGGTCTGAGGTGGCCGCG
  CAGCCCGCGGGCCTGTCGGGCCCAGCCGAGGTCGGGCCGGGGGCGGTGGGGGAGCGCACA
  CCCCGCAAGAAAGAGCCTCCGCGGGCCTCGCCCCCCGGGGGCCTGGCGGAACCGCCGGGG
  TCCGCAGGGCCTCAGGCCGGCCCTACTGTCGTGCCTGGGTCTGCGACCCCCATGGAAACT
  GGAATAGCAGAGACTCCGGAGGGGCGTCGGACCAGCCGGCGCAAGCGGGCGAAGGTAGAG
  TACAGAGAGATGGATGAAAGCTTGGCCAACCTCTCAGAAGATGAGTATTATTCAGAAGAA
  GAGAGAAATGCCAAAGCAGAGAAGGAAAAGAAGCTTCCCCCCACCACCCCTCAGCCCCAC
  CTGNAGAAGAAATGAAAGTGAGCCTGAAAGACCATCGGGTGTGGNAGGCGCAGCTTTCCG
  AGCCGACTTNCTCATGACCGGATGACTTCTCAGAAGCAGNCTGTTTCCAGAATTATCAGT
  GGACCCACACAGACCCAGAAGGGTTTTCTTTCATTANAACCGACACTGCAGNTGTGGGTG
  GATATCCAAGATCAGCTGCATTTGAGGCTCTNTNNCACATAAAAGCACCTATACAGGGTA
  CGGTGCTTGCCACCGANTCCAGTATTNANAGCGTCATGGCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015013 unedited
  ATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAATTTTATATG
  AAGTTTTATTCTCAAAATATAAAAAAAAAAACAAACCCCACACACCAAGGGACTAAGATG
  ATGTTATTTCACAGCACTTGCTTGCCTCAGTCTTTACGAAGAACACAATTCCAAACTAAT
  GGACAAGTTCCTCCCTGTGCTCTAGGTCATTCAAAGGAGGCAAGCTCCTTTGTCAAATCA
  GGAGCTCCATCAGCTGATCAGGAGCCCAGATGCCAGGGTGGATTTTCTCAGTGGGATCTA
  GTATTGCTAGAAGAGCCTTCCTTACATGGCAGAAACAGGCACATGGGCCTCTTCCCTTAG
  AATGCATCTGTCTCACATGCTTGGGGACTGCTGTGCAGGAACACCTGGTGTGGCCTGGCG
  AGGCAGCGTATACATGGCCCCCAAAAACTGGTCTGCAATTCTTCCCGCTTCTCGCAGCCC
  ACTCAGCAGAGCACCATGCACTGTGGCTGGGTAGTTACGGATCGTATGTTCTCCCGCAAA
  GAAGAGTCGTGGAATCGGCTGTGGGGCACCTGGAATCGAGGGGCCAGGAGTGATTGGCTG
  AGCCATTAAATCATAGTCATTTCCAGATGATCCTGCAGCAACATAGGAATAAGAGCCCCG
  AGCCCAGGGATCAGCACGCCAACGAGACACCACAGTTTCTTTGGGCTGAGGTACTGCACT
  GCTACCAAAAATCCCTTTGAGAATGGCAGGCATCGGCCAACATCACATCGNCACTTATGT
  TTTCATGATCCAGCAGCTTCTCTGCCACTATGCCACAGTATGGNAGCTTATGAGGTTCAG
  AAGAGAAGAGCTCACCCTGCTGGCAGTGACTGCCACATGCCCGCCAATTGACCTTGGATC
  CAGACACCGATCAAACCACACCACTTGTAAGGTGCCAACCCATCTTTGACGCAAATGTTC
  AT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015013
• ORF Size: 2559 bp
• Insert Size: 3400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015013.2, NP_055828.2
• RefSeq Size: 3030
• RefSeq ORF: 2559
• Locus ID: 23028
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
  Transcript Variant: This variant (2) lacks two alternate in-frame exons, compared to variant 1. The encoded protein (isoform b) is shorter than isoform a.