CD137 (TNFRSF9) (NM_001561) Human Untagged Clone

CAT#: SC125363

TNFRSF9 (untagged)-Human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TNFRSF9
• Synonyms: 4-1BB; CD137; CDw137; ILA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001561 edited
  GGAGTGGAAAGTTCTCCGGCAGCCCTGAGATCTCAAGAGTGACATTTGTGAGACCAGCTA
  ATTTGATTAAAATTCTCTTGGAATCAGCTTTGCTAGTATCATACCTGTGCCAGATTTCAT
  CATGGGAAACAGCTGTTACAACATAGTAGCCACTCTGTTGCTGGTCCTCAACTTTGAGAG
  GACAAGATCATTGCAGGATCCTTGTAGTAACTGCCCAGCTGGTACATTCTGTGATAATAA
  CAGGAATCAGATTTGCAGTCCCTGTCCTCCAAATAGTTTCTCCAGCGCAGGTGGACAAAG
  GACCTGTGACATATGCAGGCAGTGTAAAGGTGTTTTCAGGACCAGGAAGGAGTGTTCCTC
  CACCAGCAATGCAGAGTGTGACTGCACTCCAGGGTTTCACTGCCTGGGGGCAGGATGCAG
  CATGTGTGAACAGGATTGTAAACAAGGTCAAGAACTGACAAAAAAAGGTTGTAAAGACTG
  TTGCTTTGGGACATTTAACGATCAGAAACGTGGCATCTGTCGACCCTGGACAAACTGTTC
  TTTGGATGGAAAGTCTGTGCTTGTGAATGGGACGAAGGAGAGGGACGTGGTCTGTGGACC
  ATCTCCAGCCGACCTCTCTCCGGGAGCATCCTCTGTGACCCCGCCTGCCCCTGCGAGAGA
  GCCAGGACACTCTCCGCAGATCATCTCCTTCTTTCTTGCGCTGACGTCGACTGCGTTGCT
  CTTCCTGCTGTTCTTCCTCACGCTCCGTTTCTCTGTTGTTAAACGGGGCAGAAAGAAACT
  CCTGTATATATTCAAACAACCATTTATGAGACCAGTACAAACTACTCAAGAGGAAGATGG
  CTGTAGCTGCCGATTTCCAGAAGAAGAAGAAGGAGGATGTGAACTGTGAAATGGAAGTCA
  ATAGGGCTGTTGGGACTTTCTTGAAAAGAAGCAAGGAAATATGAGTCATCCGCTATCACA
  GCTTTCAAAAGCAAGAACACCATCCTACATAATACCCAGGATTCCCCCAACACACGTTCT
  TTTCTAAATGCCAATGAGTTGGCCTTTAAAAATGCACCACTTTTTTTTTTTTTTTGACAG
  GGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCACCACCATGGCTCTCTGCAGCCTT
  GACCTCTGGGAGCTCAAGTGATCCTCCTGCCTCAGTCTCCTGAGTAGCTGGAACTACAAG
  GAAGGGCCACCACACCTGACTAACTTTTTTGTTTTTTGTTTGGTAAAGATGGCATTTCAC
  CATGTTGTACAGGCTGGTCTCAAACTCCTAGGTTCACTTTGGCCTCCCAAAGTGCTGGGA
  TTACAGACATGAACTGCCAGGCCCGGCCAAAATAATGCACCACTTTTAACAGAACAGACA
  GATGAGGACAGAGCTGGTGATAAAAAAAAAAAAAAAAAAGCATTTTCTAGATACCACTTA
  ACAGGTTTGAGCTAGTTTTTTTGAAATCCAAAGAAAATTATAGTTTAAATTCAATTACAT
  AGTCCAGTGGTCCAACTATAATTATAATCAAAATCAATGCAGGTTTGTTTTTTGGTGCTA
  ATATGACATATGACAATAAGCCACGAGGTGCAGTAAGTACCCGACTAAAGTTTCCGTGGG
  TTCTGTCATGTAACACGACATGCTCCACCGTCAGGGGGGAGTATGAGCAGAGTGCCTGAG
  TTTAGGGTCAAGGACAAAAAACCTCAGGCCTGGAGGAAGTTTTGGAAAGAGTTCAAGTGT
  CTGTATATCCTATGGTCTTCTCCATCCTCACACCTTCTGCCTTTGTCCTGCTCCCTTTTA
  AGCCAGGTTACATTCTAAAAATTCTTAACTTTTAACATAATATTTTATACCAAAGCCAAT
  AAATGAACTGCATATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001561 unedited
  ATAGGGNNCGGCCGCGTAATTCGGCACGAGGGGTAGTTGGAAAGTTCTCCGGCAGCCCTG
  AGATCTCAANAGTGACATTTGTGAGACCAGCTAATTTGATTAAAATTCTCTTGGAATCAG
  CTTTGCTAGTATCATACCTGTGCCAGATTTCATCATGGGAAACAGCTGTTACAACATAGT
  AGCCACTCTGTTGCTGGTCCTCAACTTTGAGAGGACAAGATCATTGCAGGATCCTTGTAG
  TAACTGCCCAGCTGGTACATTCTGTGATAATAACAGGAATCAGATTTGCAGTCCCTGTCC
  TCCAAATAGTTTCTCCAGCGCAGGTGGACAAAGGACCTGTGACATATGCAGGCAGTGTAA
  AGGTGTTTTCAGGACCAGGAAGGAGTGTTCCTCCACCAGCAATGCAGAGTGTGACTGCAC
  TCCAGGGTTTCACTGCCTGGGGGCAGGATGCAGCATGTGTGAACAGGATTGTAAACAAGG
  TCAAGAACTGACAAAAAAAGGTTGTAAAGACTGTTGCTTTGGGACATTTAACGATCAGAA
  ACGTGGCATCTGTCGACCCTGGACAAACTGTTCTTTGGATGGAAAGTCTGTGCTTGTGAA
  TGGGACGAAGGAGAGGGACGTGGTCTGTGGACCATCTCCAGCCGACCTCTCTCCGGGAGC
  ATCCTCTGTGACCCCGCCTGCCCCTGCGAGAGAGCCAGGACACTCTCCGCAGATCATCTC
  CTTCTTTCTTGCGCTGACGTCGACTGCGTTGCTCTTCCTGCTGNTCTTCCTCACGCTCCG
  TTTCTCTGTTGTTAAACGGGGCAAAAGAAACTCCTGTATATATTCCAACAACCATTTATG
  AGACCAGTACAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001561
• Insert Size: 1937 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001561.4, NP_001552.2
• RefSeq Size: 1935 bp
• RefSeq ORF: 768 bp
• Locus ID: 3604
• Cytogenetics: 1p36.23
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: 'The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]'