Dermcidin (DCD) (NM_053283) Human Untagged Clone

CAT#: SC125779

DCD (untagged)-Human dermcidin (DCD)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DCD
• Synonyms: AIDD; DCD-1; DSEP; HCAP; PIF
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_053283 edited
  GGGACCCTAGATCCCAAGATCTCCAAGGATTCGGTGGCATACCCACTCCAGCACACAGAA
  GCATGAGGTTCATGACTCTCCTCTTCCTGACAGCTCTGGCAGGAGCCCTGGTCTGTGCCT
  ATGATCCAGAGGCCGCCTCTGCCCCAGGATCGGGGAACCCTTGCCATGAAGCATCAGCAG
  CTCAAAAGGAAAATGCAGGTGAAGACCCAGGGTTAGCCAGACAGGCACCAAAGCCAAGGA
  AGCAGAGATCCAGCCTTCTGGAAAAAGGCCTAGACGGAGCAAAAAAAGCTGTGGGGGGAC
  TCGGAAAACTAGGAAAAGATGCAGTCGAAGATCTAGAAAGCGTGGGTAAAGGAGCCGTCC
  ATGACGTTAAAGACGTCCTTGACTCAGTACTATAGCTGTAAGGAGAAGCTGAGAAATGAT
  ACCCAGGAGCAGCAGGCTTTACGTCTTCAGCCTAAAACCTAAAAAAAAAAAAAAAAAAAA
  AATTTAAAACAGCTATTAAACTGAAAGCATCTGGAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_053283 unedited
  GGTCAGGATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCCATTACGGGCCGGG
  GACCCTANATCCCAANATCTCCAGGGTTCGGTGGCGTACCCACTCCAGCACACAGAAGCA
  TGAGGTTCATGACTCTCCTCTTCCTGACAGCTCTGGCAGGAGCCCTGGTCTGTGCCTATG
  ATCCAGAGGCCGCCTCTGCCCCAGGATCGGGGAACCCTTGCCATGAAGCATCAGCAGCTC
  AAAAGGAAAATGCAGGTGAAGACCCAGGGTTAGCCAGACAGGCACCAAAGCCAAGGAAGC
  AGAGATCCAGCCTTCTGGAAAAAGGCCTAGACGGAGCAAAAAAAGCTGTGGGGGGACTCG
  GAAAACTAGGAAAAGATGCAGTCGAAGATCTAGAAAGCGTGGGTAAAGGAGCCGTCCATG
  ACGTTAAAGACGTCCTTGACTCAGTACTATAGCTGTAAGGAGAAGCTGAGAAATGATACC
  CAGGAGCAGCAGGCTTTACGTCTTCAGCCTAAAACCTAAAAAAAAAAAAAAAAAAAAAAT
  TTAAAACAGCTATTAAACTGAAAGCATCTGGAAAAAAAAAAAANNAAAAAAAAAAAAAAA
  ACATGGTCGGCCGCCTCGGCCCTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCT
  GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCGTCTCCTGGGCCTGGAAG
  GTGCCACTCCGTGCCCACCAGCCTTGGCCTATAAAATTAAGTTGCATCATTTTGTCTGAC
  TAGGTGTCCTTCTAAATATTATGGGGTGAGGGGGGTNGGGTTTGAACCAGGGGCAATTTT
  GAAAAACACCCGGAGGGGCTGCGGGGGCTATTGGAAACAAGTGGAGTGGGGGGGCCATCT
  TGGCTATGGGATCTCCCCTCTGGGGTCAACCATT
  
• Restriction Sites: Please inquire
• ACCN: NM_053283
• ORF Size: 333 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_053283.1, NP_444513.1
• RefSeq Size: 458
• RefSeq ORF: 333
• Locus ID: 117159
• Protein Families: Secreted Protein
• Gene Summary: This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) lacks an alternate exon in the 3' coding region, resulting in a frameshift compared to variant 2. The encoded isoform (1) has a distinct C-terminus , and is shorter, compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.