PGPEP1 (BC042138) Human Untagged Clone

CAT#: SC125852

PGPEP1 (untagged)-Human pyroglutamyl-peptidase I, mRNA (cDNA clone MGC:52179 IMAGE:5935845), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PGPEP1
• Synonyms: 5-oxoprolyl-peptidase; FLJ20208; MGC10812; Pcp; PGP; PGP-I; PGPI; pyroglutamyl-peptidase I; pyrrolidone-carboxylate peptidase
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC042138 edited
  GAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGC
  CCGATCCCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTG
  GGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGAGATGGGATCTCACTATATTGC
  CCTGGCTGGTCTTGAACTTCCGGGCTCAAATGATCCTTCCACCTCGGCCTCCCAAAGAAG
  CTGGGATTATAGGTGTGAGCCACCGAGCCCTGCCATCAGGAGCTAGAAAAGCTAGGCCTT
  GGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGA
  CTCATCCCCGCCCTGTGGGAGAAGCACAGTCCACAGCTGGTGGTGCATGTGGGGGTGTCA
  GGCATGGCGACCACAGTCACACTGGAGAAATGTGGACACAACAAGGGCTACAAGGGGCTG
  GACAACTGCCGCTTTTGCCCCGGCTCCCAGTGCTGCGTGGAGGACGGGCCTGAAAGCATT
  GACTCCATCATCGACATGGATGCTGTGTGCAAGCGAGTCACCACGTTGGGCCTGGATGTG
  TCGGTGACCATCTCGCAGGATGCCGGCAGATATCTCTGCGACTTTACCTACTACACCTCT
  TTGTACCAGAGTCACGGTCGATCAGCCTTCGTCCACGTGCCCCCACTGGGGAAGCCGTAC
  AACGCGGACCAGCTGGGCAGGGCACTGAGAGCCATCATTGAGGAGATGTTGGACCTCCTG
  GAGCAGTCAGAGGGCAAAATCAACTATTGCCACAAACACTGAGGGACGCTCAGGTCTCCT
  AAGACCTCATCCTGCTGGGGACCCCACGAGGGGACATCCACCCTCTGGGGTGTGGCCAGG
  AAAAGACAAGCTCTTCAGCTTGGGGATCCGATCTGGAAGAGAGATTCTGATCTGCCCACC
  TCCTCTTCCTCCTTCTCTACAAAAGCTCCGGTTGATTCGAGGGAAGTGGTGAAAAATTTT
  TTTTCTCCCATTTTCCTCCCTGCATCTGGGGACACAGCTGCCGTGACCAGGGAGGCCAGC
  CTGGGAGGTCCAGATGCCCAGGGAGAATCTTGGTCTGGTGAATCCATGAGCTGCGATACC
  ACGGCTGGGGCCATATGTTCACCTGCTTTCCTGTCCGTTGGTGAAGGAATTTCAGAATTC
  ATTTTATATCCAAGACTGGCTTTTACCAAATTTAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC042138 unedited
  CCCCGCAGTCAGGATTTGTATACGACTTATATAGGGCGGCCGCGAATTCGCACGAGGGAG
  GCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCG
  ATCCCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGG
  AACACACCGTGAACGCCAGTTGGATTGCAGTTCAGAGATGGGATCTCACTATATTGCCCT
  GGCTGGTCTTGAACTTCCGGGCTCAAATGATCCTTCCACCTCGGCCTCCCAAAGAAGCTG
  GGATTATAGGTGTGAGCCACCGAGCCCTGCCATCAGGAGCTAGAAAAGCTAGGCCTTGGC
  GACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTC
  ATCCCCGCCCTGTGGGAGAAGCACAGTCCACAGCTGGTGGTGCATGTGGGGGTGTCAGGC
  ATGGCGACCACAGTCACACTGGAGAAATGTGGACACAACAAGGGCTACAAGGGGCTGGAC
  AACTGCCGCTTTTGCCCCGGCTCCCAGTGCTGCGTGGAGGACGGGCCTGAAAGCATTGAC
  TCCATCATCGACATGGATGCTGTGTGCAAGCGAGTCACCACGTTGGGCCTGGATGTGTCG
  GTGACCATCTCGCAGGATGCCGGCAGATATCTCTGCGACTTTACCTACTACACCTCTTTG
  TACCAGAGTCACGGTCGATCAGCCTTCGTCCACGTGCCCCCACTGGGGAAGCCGTACAAC
  GCGGACCAGCTGGGCAGGGCACTGAGAGCCATCATTGAGGAGATGTTGGACTCCTGGAGC
  AGTCAGAGGGCAAATCACTATTGCCACAAAACTGAGGGAC
  
• Restriction Sites: Please inquire
• ACCN: BC042138
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC042138.1, AAH42138.1
• RefSeq Size: 1251
• Locus ID: 54858
• Protein Families: Druggable Genome, Protease
• Gene Summary: The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. [provided by RefSeq, Jul 2016]