C4BPB (NM_000716) Human Untagged Clone

CAT#: SC125997

C4BPB (untagged)-Human complement component 4 binding protein, beta (C4BPB), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C4BPB
• Synonyms: C4BP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000716 edited
  ATTCCCAGAAACCAGGAAATTTCTGAAACTGAGTTTTAAACCTGGCAACTCTTTTACCAT
  CCCTTTGTATTTTTGCAGTTCCTCCCTATACCAGCTTCCTTACAGCTGTTCTGATTTCCT
  GTCGTAAGATTTTTTCTTTTCATTTTCTCCAGGGAGGGTAAATCAATATAACCTCTTCTC
  TAGAGAGGAGGTGGTTAGGTTGGTCTTAAGCAGTGTTAGAAGATCTATTTTTTTTCAAAC
  CAGGTGTCTGAGCTGGGTGAATTCCAGCCTGGGGAGAGGACTTTGATCACCAGATGTTTT
  TTTGGTGTGCGTGCTGTCTTATGGTTGCGTGGCGAGTTTCTGCTTCAGATGAGCACTGTC
  CAGAGCTTCCTCCAGTGGACAATAGCATATTTGTCGCAAAGGAGGTGGAAGGACAGATTC
  TGGGGACTTACGTTTGTATCAAGGGCTACCACCTGGTAGGAAAGAAGACCCTTTTTTGCA
  ATGCCTCTAAGGAGTGGGATAACACCACTACTGAGTGCCGCTTGGGCCACTGTCCTGATC
  CTGTGCTGGTGAATGGAGAGTTCAGTTCTTCAGGGCCTGTGAATGTAAGTGACAAAATCA
  CGTTTATGTGCAATGACCACTACATCCTCAAGGGCAGCAATCGGAGCCAGTGTCTAGAGG
  ACCACACCTGGGCACCTCCCTTTCCCATCTGCAAAAGTAGGGACTGTGACCCTCCTGGGA
  ATCCAGTTCATGGCTATTTTGAAGGAAATAACTTCACCTTAGGATCCACCATTAGTTATT
  ACTGTGAAGACAGGTACTACTTAGTGGGCGTGCAGGAGCAGCAATGCGTTGATGGGGAGT
  GGAGCAGTGCACTTCCAGTCTGCAAGTTGATCCAGGAAGCTCCCAAACCAGAGTGTGAGA
  AGGCACTTCTTGCCTTTCAGGAGAGTAAGAACCTCTGCGAAGCCATGGAGAACTTTATGC
  AACAATTAAAGGAAAGTGGCATGACAATGGAGGAGCTAAAATATTCTCTGGAGCTGAAGA
  AAGCTGAGTTGAAGGCAAAATTGTTGTAACACTACAGCTGAGCAGATGTAATAGAAATAA
  ACCTATGAATAAATTTTCTTCTTGGTTCTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000716 unedited
  TCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCCATTACGGCCGGGGATTC
  CCAGAAACCAGGAAATTTCTGAAACTGAGTTTTAAACCTGGCAACTCTTTTACCATCCCT
  TTGTATTTTTGCAGTTCCTCCCTATACCAGCTTCCTTACAGCTGTTCTGATTTCCTGTCG
  TAAGATTTTTTCTTTTCATTTTCTCCAGGGAGGGTAAATCAATATAACCTCTTCTCTAGA
  GAGGAGGTGGTTAGGTTGGTCTTAAGCAGTGTTAGAAGATCTATTTTTTTTCAAACCAGG
  TGTCTGAGCTGGGTGAATTCCAGCCTGGGGAGAGGACTTTGATCACCAGATGTTTTTTTG
  GTGTGCGTGCTGTCTTATGGTTGCGTGGCGAGTTTCTGCTTCAGATGAGCACTGTCCAGA
  GCTTCCTCCAGTGGACAATAGCATATTTGTCGCANAGGAGGTGGAAGGACAGATTCTGGG
  GACTTACGTTTGTATCAAGGGCTACCACCTGGTANGAAAGAAGACCCTTTTTTGCAATGC
  CTCTAAGGAGTGGGATAACACCACTACTGAGTGCCGCTTGGGCCACTGTCCTGATCCTGT
  GCTGGTGAATGGAGAGTTCAGTTCTTCAGGGCCCCTGTGATGTAGTGACANNATCACGTT
  TATGTGCAATGACCACTACATCCTCAAGGGCAGNCATCGNAGCCAGTGTCTAGAGGACAC
  ACCTGGGCACCTNCCNTTCCCATCTGCAAAGTAGGNACTGTGACCCTCCTGGGATCCAGT
  TCATGGCTATTTTGAAGGNATAACTTTCACCTTAGATCCACCATTAGTTATTACTGTGAA
  GACAGGTACTACTTAGTGGGCGTGCANGAGCCAGCATGCGTTGATGGGGAGTGNAGCAGT
  GCACTTCCAGTCTGCAGTTGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000716
• ORF Size: 759 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_000716.3, NP_000707.1
• RefSeq Size: 1131
• RefSeq ORF: 759
• Locus ID: 725
• Protein Pathways: Complement and coagulation cascades
• Gene Summary: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1), also known as A19, represents the longest transcript and encodes the longer isoform (1).