Aldolase (ALDOA) (BC010568) Human Untagged Clone

CAT#: SC126036

(untagged)-Human cDNA clone MGC:18171 IMAGE:4155253, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDOA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC010568 edited
  CAGCTGAATAGGCTGCGTTCTCTTGGAACGCGCAGCAGAACGAGGTTCTGGTGACCCTAG
  CCGCGTTCGCTCCTTAGTCCTTTCGCCTACCCACCGGCGTACCAGGCAGACCCACCCCGT
  CCTGTGCCAGGAAAGCACTGCCACCGGCACCATGCCCCACCCATACCCAGCACTGACCCC
  GGAGCAGAAGAAGGAGCTGTCTGACATCGCTCACCGCATTGTGGCTCCGGGCAAGGGCAT
  CCTGGCTGCAGATGAGTCCACCGGAAGCATTGCCAAGCGCCTGCAGTCCATTGGCACCGA
  GAACACCGAGGAGAACAGGCGCTTCTACCGCCAGCTGCTGCTGACTGCAGACGACCGTGT
  GAATCCCTGCATTGGGGGGGTGATCCTCTTCCACGAGACACTGTACCAGAAGGCAGATGA
  TGGACGTCCCTTCCCCCAAGTTATCAAGTCCAAGGGTGGTGTTGTGGGCATTAAGGTAGA
  TAAGGGTGTGGTGCCCCTGGCAGGAACCAATGGCGAGACAACTACCCAGGGGCTGGATGG
  GCTGTCTGAACGCTGTGCCCAGTATAAGAAGGATGGAGCCGACTTTGCCAAGTGGCGCTG
  TGTGCTAAAGATTGGGGAACATACTCCCTCGGCCCTGGCCATCATGGAAAATGCCAATGT
  TCTGGCCCGTTATGCCAGCATCTGCCAGCAGAATGGCATTGTACCCATTGTGGAGCCTGA
  AATTCTCCCTGATGGGGACCATGACTTGAAGCGCTGCCAGTATGTTACTGAGAAGGTCCT
  GGCGGCTGTCTACAAGGCTCTGAGCGACCACCATGTCTATCTGGAAGGCACATTGCTGAA
  GCCCAACATGGTCACCCCTGGCCATGCTTGCACCCAGAAATTTTCCAATGAGGAGATTGC
  CATGGCAACGGTCACAGCACTTCGTCGCACAGTGCCCCCTGCTGTCACTGGGGTCACTTT
  CCTGTCTGGAGGGCAGAGTGAGGAAGAGGCATCCATCAACCTCAATGCTATCAACAAGTG
  CCCCCTGCTGAAGCCATGGGCCTTGACTTTCTCCTATGGTCGAGCCCTGCAGGCCTCTGC
  TCTAAAGGCCTGGGGTGGGAAGAAGGAGAACCTGAAGGCAGCCCAGGAGGAGTACATCAA
  GCGCGCCCTGGCCAACAGCCTCGCTTGTCAAGGAAAGTATACCCCAAGTGGCCAGTCTGG
  AGCCGCAGCCAGTGAATCTCTCTTCATCTCTAACCATGCCTACTAACCAGAGCTGAACTA
  AGGCTGCTCCATCAACACTCCAGGCCCCTGCCTACCCACTTGCTATTGAAGAGGGGTCTT
  CAGGCTCTTTCCCATCACTCTTGCTGCTGCCCTCGTGTGCGGTGTTGTCTGTGAATGCTA
  AATCTGCCATCCCTTCCAGCCCACTGCCAATAAACAACTATTTAAGGGGGAAAAAAAAAA
  AAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC010568 unedited
  GGGCTCAGGATTTTGTAATACGACTTTACTATAGGGCGGCCGCGCAATTCGATCTGGTAC
  CGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCAGCTGAATAGGCTGCGTTC
  TCTTGGAACGCGCAGCAGAACGAGGTTCTGGTGACCCTAGCCGCGTTCGCTCCTTAGTCC
  TTTCGCCTACCCACCGGCGTACCAGGCAGACCCACCCCGTCCTGTGCCAGGAAAGCACTG
  CCACCGGCACCATGCCCCACCCATACCCAGCACTGACCCCGGAGCAGAAGAAGGAGCTGT
  CTGACATCGCTCACCGCATTGTGGCTCCGGGCAAGGGCATCCTGGCTGCAGATGAGTCCA
  CCGGAAGCATTGCCAAGCGCCTGCAGTCCATTGGCACCGAGAACACCGAGGAGAACAGGC
  GCTTCTACCGCCAGCTGCTGCTGACTGCAGACGACCGTGTGAATCCCTGCATTGGGGGGG
  TGATCCTCTTCCACGAGACACTGTACCAGAAGGCAGATGATGGACGTCCCTTCCCCCAAG
  TTATCAAGTCCAAGGGTGGTGTTGTGGGCATTAAGGTAGATAAGGGTGTGGTGCCCCTGG
  CAGGAACCAATGGCGAGACAACTACCCAGGGGCTGGATGGGCTGTCTGAACGCTGTGCCC
  AGTATAAGAAGGATGGAGCCGACTTTGCCAAGTGGCGCTGTGTGCTAAAGATTGGGGAAC
  ATACTCCCTCGGCCCTGGCCATCATGGGAAATGCCAATGTTCTGGGCCGTTATGCCAGCA
  TCTGCCAGCAGAATGGCATTGTACCCATTGTGGAGCCTNGAATTCTCCCTGATGGGGACC
  CATGACTGAAGCGCTGCCAGTATGTTACTGAGAAGGTCCTGGCNGCTGTGCTACAGGCTC
  TGAGCGC
  
• Restriction Sites: NotI-NotI
• ACCN: BC010568
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC010568.1, AAH10568.1
• RefSeq Size: 1455 bp
• Locus ID: 226
• Cytogenetics: 16p11.2
• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway
• Gene Summary: 'This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]'