RFXDC1 (RFX6) (NM_173560) Human Untagged Clone

CAT#: SC126045

RFX6 (untagged)-Human regulatory factor X, 6 (RFX6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RFX6
• Synonyms: dJ955L16.1; MTCHRS; MTFS; RFXDC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_173560 edited
  GGCTGGGGCTCCGCTGGGGAACCGGCCGAGCGGCGCGCGCGGAGGTGTCCGGCGGCCAGG
  AGGATGGCCAAGGTCCCGAAGCTGGAAGACACCTTCCTGCAGGCGCAGCCTGCGCCCCAA
  CTGTCCCCGGGGATCCAGGAAGACTGCTGTGTGCAGCTCCTGGGCAAGGGCTTGCTAGTC
  TATCCGGAAGAAACAGTGTACCTGGCGGCCGAAGGGCAGCCCGGGGGCGAGCAGGGCGGC
  GGGGAGAAAGGCGAAGACCCGGAGCTGCCGGGGGCAGTGAAATCAGAAATGCACTTAAAC
  AATGGTAACTTTTCCTCTGAAGAAGAGGACGCCGACAACCACGACAGCAAAACCAAAGCA
  GCGGATCAATACCTGTCTCAGAAGAAAACCATCACGCAGATTGTGAAGGATAAAAAGAAG
  CAGACACAGCTCACGCTGCAGTGGCTTGAAGAGAATTACATTGTATGTGAAGGAGTTTGC
  TTACCACGGTGCATTCTTTATGCACACTACTTAGATTTCTGTAGGAAAGAGAAATTAGAG
  CCAGCCTGTGCGGCCACCTTTGGAAAGACAATTCGCCAGAAGTTTCCCCTCCTAACAACA
  AGGCGGCTTGGAACAAGAGGCCATTCAAAGTATCATTACTATGGGATTGGCATCAAAGAG
  AGCAGTGCATATTACCACTCCGTTTATTCTGGAAAGGGCTTGACAAGGTTTTCTGGAAGC
  AAGCTAAAGAATGAGGGTGGCTTCACTCGTAAATATTCGCTTAGCTCAAAAACTGGAACA
  CTTCTTCCAGAATTCCCCAGCGCTCAACACCTTGTATACCAAGGATGCATTTCTAAGGAC
  AAGGTTGATACGCTCATAATGATGTACAAAACTCACTGCCAGTGTATCCTGGACAATGCA
  ATTAATGGAAACTTTGAAGAGATCCAGCATTTTTTATTACACTTTTGGCAAGGAATGCCT
  GACCATCTCCTTCCCCTGCTCGAAAATCCTGTTATCATTGATATTTTCTGTGTTTGTGAC
  TCAATTCTTTATAAGGTTCTTACAGATGTACTCATTCCTGCAACAATGCAAGAAATGCCT
  GAAAGCTTATTAGCAGACATAAGAAATTTTGCTAAAAATTGGGAACAGTGGGTTGTTTCA
  TCCTTGGAAAACTTGCCAGAAGCTCTAACTGACAAGAAAATACCTATTGTGCGAAGATTT
  GTATCTTCTCTGAAACGACAAACATCTTTCTTACATCTTGCCCAGATTGCCAGACCAGCT
  CTCTTTGACCAGCATGTCGTTAATTCTATGGTGTCTGATATTGAAAGGGTTGATTTGAAC
  AGCATTGGCTCTCAAGCCCTTCTTACCATTTCAGGCAGCACAGACACTGAATCTGGTATC
  TACACTGAACATGACTCTATCACTGTGTTCCAAGAACTGAAGGATCTCCTTAAGAAGAAT
  GCCACTGTGGAGGCTTTTATTGAATGGTTGGATACTGTGGTAGAACAGAGAGTTATTAAG
  ACCAGCAAACAAAATGGAAGGTCATTAAAGAAGAGAGCTCAAGACTTTCTGTTAAAGTGG
  AGTTTTTTTGGTGCTCGAGTAATGCATAATCTCACCTTGAACAATGCATCCAGTTTTGGT
  TCTTTTCATTTGATTCGAATGCTTCTCGATGAATACATTCTCCTGGCCATGGAGACCCAG
  TTTAATAATGACAAAGAGCAGGAGTTACAGAATTTATTGGACAAGTATATGAAGAATTCA
  GATGCGAGTAAAGCTGCTTTCACTGCTTCTCCGAGTTCATGCTTTCTGGCCAACCGTAAT
  AAAGGGAGCATGGTTTCCAGCGACGCTGTGAAGAATGAAAGCCACGTGGAGACAACCTAT
  CTCCCTCTGCCATCCAGTCAACCTGGAGGCCTAGGCCCTGCTCTGCACCAGTTCCCTGCT
  GGGAACACAGACAACATGCCGCTCACAGGTCAAATGGAGCTTTCACAGATTGCTGGTCAT
  CTGATGACACCACCCATTTCTCCAGCCATGGCAAGCCGAGGAAGTGTCATTAACCAAGGA
  CCAATGGCAGGGAGGCCCCCAAGTGTGGGCCCAGTACTGTCAGCTCCATCACACTGCTCC
  ACATACCCAGAGCCCATTTATCCCGCTCTCCCTCAAGCCAATCATGACTTTTATAGCACC
  AGCTCTAACTACCAGACTGTGTTTAGGGCACAGCCCCACTCCACATCAGGACTCTATCCT
  CATCACACCGAGCATGGTCGATGCATGGCTTGGACTGAACAGCAGCTTTCAAGAGACTTC
  TTCAGTGGCAGCTGTGCGGGGTCTCCATATAACTCCCGGCCACCGTCTAGCTATGGCCCA
  TCCCTGCAAGCCCAGGATTCACACAATATGCAGTTTTTAAATACAGGAAGCTTCAATTTC
  TTGAGCAACACAGGAGCTGCCAGCTGCCAAGGAGCAACACTGCCTCCTAATTCACCAAAT
  GGATACTATGGAAGCAACATAAACTACCCAGAGTCTCACAGGCTCGGATCAATGGTGAAT
  CAGCACGTTTCTGTCATCAGCAGCATTCGTTCACTGCCCCCCTACAGTGACATCCACGAT
  CCACTTAACATTTTAGATGACAGTGGTAGAAAACAGACCAGCTCGTTTTACACAGACACA
  TCATCTCCAGTTGCATGTCGAACTCCAGTCCTAGCTTCCAGTTTGCAAACCCCAATTCCT
  TCTTCCTCATCCCAATGTATGTATGGAACTTCCAACCAGTATCCAGCTCAAGAAACCCTG
  GACTCCCATGGAACAAGCAGTAGAGAAATGGTGTCCTCTTTACCACCTATCAACACTGTG
  TTCATGGGAACAGCAGCTGGAGGCACTTAAACCACCAATGTGGGAGGGGGTGCTAAAACT
  TTAAAAAAAATCTCTACTGTGCAAATATCATTATTCACTCAGACTTCCATAAGAGTAAAT
  AAAAATGAATATGCAGTGGCTGACATTGTTTTAAAGTCACTGGTACTATGGACAACTCCA
  TAGTGAATGGAGATACTTGCAGAGCTTGTCATGCACACTAAGAGTTTAAAATGTGAGCTC
  ATTATTAATCATAGTTTCAAAATTATCAAATAAAACCAGTGAAGATCTGAAGATGCAAAC
  ATTTCAACTATGAAGATTTACATTTCACTTTCTAATTTATTAAACATCTGTGTGCCTTTT
  TATCTTTGGTTTCTTTTAAAAAGTATATTTAATGCCTTTACAATACCTTTAATTTATTAG
  GATCTCAGAATCATTGTTTACTATCCCTTATTTGACAAAAAGTCAAATGTGTATGTTCTA
  CCTCCAACGGAAATGTTTACAAGGTCAAGACTTAATTCAATTCAGACAAGACCAAAGTTG
  CTTGACTTCAATTCCTGTGCATTAGTGTGATGATTTCTGTCACATAGCAGCATTCCGATT
  CTATGTAACTGAATGGAGATGATAAGTGCTTTCCCCTCTTTATTTAAAAAAGATTAAAAG
  GAATAAAAGAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_173560 unedited
  GTGAGTCATATTTTGTATACGACTCATATAGGCGGCCGCATAACTTCGTATAGCATACAT
  TATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGGCTG
  GGGCTCCGCTGGGGAACCGGCCGAGCGGCGCGCGCGGAGGTGTCCGGCGGCCAGGAGGAT
  GGCCAAGGTCCCGAAGCTGGAAGACACCTTCCTGCAGGCGCAGCCTGCGCCCCAACTGTC
  CCCGGGGATCCAGGAAGACTGCTGTGTGCAGCTCCTGGGCAAGGGCTTGCTAGTCTATCC
  GGAAGAAACAGTGTACCTGGCGGCCGAAGGGCAGCCCGGGGGCGAGCAGGGCGGCGGGGA
  GAAAGGCGAAGACCCGGAGCTGCCGGGGGCAGTGAAATCAGAAATGCACTTAAACAATGG
  TAACTTTTCCTCTGAAGAAGAGGACGCCGACAACCACGACAGCAAAACCAAAGCAGCGGA
  TCAATACCTGTCTCAGAAGAAAACCATCACGCAGATTGTGAAGGATAAAAAGAAGCAGAC
  ACAGCTCACGCTGCAGTGGCTTGAAGAGAATTACATTGTATGTGAAGGAGTTTGCTTACC
  ACGGTGCATTCTTTATGCACACTACTTAGATTTCTGTAGGAAAGAGAAATTAGAGCCAGC
  CTGTGCGGCCACCTTTGGAAAGACAATTCGCCAGAAGTTTCCCCTCCTAACAACAAGGCG
  GCTTGGAACAAGAGGCCATTCANAGTATCATTACTATGGGATTGGCATCAAAGAGAGCAG
  TGCATATTACCACTCCGTTTATTCTGGAAAGGGCTTGACANGGTTTTCTGGAAGCAAGCT
  AAAGAATGAGGTGGCTTCACTCGTAAATATTCGCTTANCTCAAAACTGGAACACTTCTCN
  
• Restriction Sites: Please inquire
• ACCN: NM_173560
• ORF Size: 2787 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_173560.1, NP_775831.1
• RefSeq Size: 3538
• RefSeq ORF: 2787
• Locus ID: 222546
• Protein Families: Transcription Factors
• Gene Summary: The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis. [provided by RefSeq, Sep 2010]