CHCHD2 (BC066331) Human Untagged Clone

CAT#: SC126068

CHCHD2 (untagged)-Human coiled-coil-helix-coiled-coil-helix domain containing 2, mRNA (cDNA clone MGC:87328 IMAGE:4792941), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHCHD2
• Synonyms: 16.7kD protein; aging-associated gene 10 protein; C7orf17; coiled-coil-helix-coiled-coil-helix domain containing 2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC066331 edited
  GTTGTCACACGTCCGGAGGCCTAGCCGTCGCGTACCTAGGATGCCGCGTGGAAGCCGAAG
  CCGCACCTCCCGCATGGCCCCTCCGGCCAGCCGGGCCCCTCAGATGAGAGCTGCACCCAG
  GCCAGCACCAGTCGCTCAGCCACCAGCAGCGGCACCCCCATCTGCAGTTGGCTCTTCTGC
  TGCTGCGCCCCGGCAGCCAGTTCTGATGGCCCAGATGGCAACCACTGCAGCTGGCGTGGC
  TGTGGGCTCTGCTGTGGGGCACACATTGGGTCACGCCATTACTGGGGGCTTCAGTGGAGG
  AAGTAATGCTGAGCCTGCGAGGCCTGACATCACTTACCAGGAGCCTCAGGGAACCCAGCC
  AGCACAGCAGCAGCAGCCTTGCCTCTATGAGATCAAACAGTTTCTGGAGTGTGCCCAGAA
  CCAGGGTGACATCAAGCTCTGTGAGGGTTTCAATGAGGTGCTGAAACAGTGCCGACTTGC
  AAACGGATTGGCCTAATGAAGAAGTTCAACCTGGAGAGATGGAAAATCAGCTCTCATAAC
  TAAGTTAATTTAGTATAAAAATAGAATTGATAGTGAGGGTATAAAGTGTAACCATCAGTT
  AAACCTCTCCTGTCATTCCTAGCTTCCTTGCTTCAGAATTGAAATGGAAGTGGGTGTCCC
  TACTCTGTAGAATCTGGGACTGGGCAAATGTTTGTGTGGCCTCCTTAAACTAGCTGTTAT
  GTTATGATTTTATTCTTTGTGAGTTAATTAGAATAAAGTCATTTTCTTCCAAGGAAAAAA
  AAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC066331 unedited
  GGGTCAAAATTTGTATACGACTCATATAGGCGGCCGCATAACTTCGTATAGCATACATTA
  TACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGTTGTCA
  CACGTCCGGAGGCCTAGCCGTCGCGTACCTAGGATGCCGCGTGGAAGCCGAAGCCGCACC
  TCCCGCATGGCCCCTCCGGCCAGCCGGGCCCCTCAGATGAGAGCTGCACCCAGGCCAGCA
  CCAGTCGCTCAGCCACCAGCAGCGGCACCCCCATCTGCAGTTGGCTCTTCTGCTGCTGCG
  CCCCGGCAGCCAGTTCTGATGGCCCAGATGGCAACCACTGCAGCTGGCGTGGCTGTGGGC
  TCTGCTGTGGGGCACACATTGGGTCACGCCATTACTGGGGGCTTCAGTGGAGGAAGTAAT
  GCTGAGCCTGCGAGGCCTGACATCACTTACCAGGAGCCTCAGGGAACCCAGCCAGCACAG
  CAGCAGCAGCCTTGCCTCTATGAGATCAAACAGTTTCTGGAGTGTGCCCAGAACCAGGGT
  GACATCAAGCTCTGTGAGGGTTTCAATGANGTGCTGANACAGTGCCGACTTGCANACGGA
  TTGGCCTAATGAAGAAGTTCAACCTGGAGAGATGGAAAATCAGCTCTCATAACTAAGTTA
  ATTTAGTATAANAATAGAATTGATAGTGAGGGTATAAAGTGTAACCATCAGGTTAACCTC
  TCCTGTCATTCCTAGCTTCCTTGCTTCAGAATTGAATGGAAGTGGGTGTCCCTACTCTGT
  AGAATCTGGGACTGGGCAAATGTTTGTGTGGCCTNCTTAAACTAGCTGTTATGGTATGAT
  TTTAATCCTTGNNGAGTAAATTANAAATAAGTCATTTTCTTCCCAGGAAAAAAAAAAAAA
  ACTCN
  
• Restriction Sites: NotI-NotI
• ACCN: BC066331
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC066331.1, AAH66331.1
• RefSeq Size: 789
• Locus ID: 51142
• Gene Summary: The protein encoded by this gene belongs to a class of eukaryotic CX(9)C proteins characterized by four cysteine residues spaced ten amino acids apart from one another. These residues form disulfide linkages that define a CHCH fold. In response to stress, the protein translocates from the mitochondrial intermembrane space to the nucleus where it binds to a highly conserved 13 nucleotide oxygen responsive element in the promoter of cytochrome oxidase 4I2, a subunit of the terminal enzyme of the electron transport chain. In concert with recombination signal sequence-binding protein J, binding of this protein activates the oxygen responsive element at four percent oxygen. In addition, it has been shown that this protein is a negative regulator of mitochondria-mediated apoptosis. In response to apoptotic stimuli, mitochondrial levels of this protein decrease, allowing BCL2-associated X protein to oligomerize and activate the caspase cascade. Pseudogenes of this gene are found on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]