Apc10 (ANAPC10) (NM_014885) Human Untagged Clone

CAT#: SC126079

ANAPC10 (untagged)-Human anaphase promoting complex subunit 10 (ANAPC10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANAPC10
• Synonyms: APC10; DOC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014885 edited
  GTTCAACGCCGTTGGCGAAGCCAGCTGCTGGAGGTGCCGAGAATCTGAGTTTCGGCAAGC
  AGCCAGAATATTTTAAAAATGACTACACCAAACAAGACACCTCCTGGTGCTGACCCCAAG
  CAGTTGGAAAGGACTGGAACAGTACGGGAAATTGGGTCACAAGCTGTTTGGTCACTCTCA
  TCTTGCAAACCAGGATTTGGAGTGGATCAGTTACGAGATGACAATCTAGAAACTTATTGG
  CAATCAGATGGTTCCCAGCCTCATTTAGTGAACATCCAATTCAGAAGAAAAACAACAGTG
  AAGACATTATGTATTTATGCAGACTACAAATCTGATGAAAGCTATACTCCAAGCAAGATC
  TCAGTCAGAGTAGGAAATAATTTTCACAACCTTCAAGAAATTCGGCAACTTGAGTTGGTG
  GAACCAAGTGGCTGGATTCATGTTCCCTTAACTGACAATCATAAGAAGCCAACTCGTACA
  TTCATGATACAGATTGCTGTTCTAGCCAATCACCAGAATGGAAGAGACACCCATATGAGA
  CAAATTAAAATATACACACCAGTAGAAGAGAGCTCCATTGGTAAATTTCCTAGATGTACA
  ACTATAGATTTCATGATGTATCGTTCAATAAGGTGACTTTAAAATGAGACGAAAATCATT
  AAACGTATCTTTGTTTTATCCTGTATTTAAATAATATATCATGTACCTTTATTGAACAAG
  GCATCCGTTATATCTAATTTTGTATATGTTTAAAAATATTTTATTGTAACTTTGACAAAT
  AAATTTGGGGTCATATTATCTTTATTTTCTTTAACATGTAATAAAGCTCACATATTTTAC
  ATTACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014885 unedited
  GGGGCAGGATTTGTATACGACTCCACTATAGGCGGCGCGCGAATTCGCCATTACGGCCGG
  GGGTTCAACGCCGTTGGCGAAGCCAGCTGCTGGAGGTGCCGAGAATCTGAGTTTCGGCAA
  GCAGCCAGAATATTTTAAAAATGACTACACCAAACAAGACACCTCCTGGTGCTGACCCCA
  AGCAGTTGGAAAGGACTGGAACAGTACGGGAAATTGGGTCACAAGCTGTTTGGTCACTCT
  CATCTTGCAAACCAGGATTTGGAGTGGATCAGTTACGAGATGACAATCTAGAAACTTATT
  GGCAATCAGATGGTTCCCAGCCTCATTTAGTGAACATCCAATTCAGAAGAAAAACAACAG
  TGAAGACATTATGTATTTATGCAGACTACAAATCTGATGAAAGCTATACTCCAAGCAAGA
  TCTCAGTCAGAGTAGGAAATAATTTTCACAACCTTCAAGAAATTCGGCAACTTGAGTTGG
  TGGAACCAAGTGGCTGGATTCATGTTCCCTTAACTGACAATCATAAGAAGCCAACTCGTA
  CATTCATGATACAGATTGCTGGTCTAGCCAATCACCAGAATGGAAGAGACACCCATATGA
  GACAAATTAAAATATACACACCAGTAGAAGAGAGCTCCATTGGGAAATTTCCTAGATGTA
  CAACTATAGATTTCATGATGTATCGTTCAATAAGGTGACTTTAAAATGAGACGAANATCA
  TTAAACGTATCTTTGGTTTATCCTGTGTTTAAATAATATATCATGTGACTTTATTGAACA
  GGGCGTCCGTTATATCTAATTTTGTATATGTGTAAAAATATTTTATTNGTGACTTTGAGC
  AATAAATTTGGGGTCATATTATCTTTTATTTTCTTTAACTGGAGATAAGCTCACATATTT
  TACATTACCCCNNNAAAAAAAAAAANAAAAAAAAAAACTGTGGGCCGCCTCGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_014885
• ORF Size: 558 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014885.1, NP_055700.1
• RefSeq Size: 941
• RefSeq ORF: 558
• Locus ID: 10393
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
• Gene Summary: ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). [supplied by OMIM, Feb 2011]
  Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.