XRCC4 (NM_022550) Human Untagged Clone

CAT#: SC126125

XRCC4 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 3


  "NM_022550" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol XRCC4
Synonyms SSMED
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_022550 edited
GGGGACCGGAAGTAGAGTCACGGAGAGGTAGGATCCGGAAGTGGGGCTGCCTCTTTAAAT
AACAAAAATCTGAGGTATTAAGAAATGGAGAGAAAAATAAGCAGAATCCACCTTGTTTCT
GAACCCAGTATAACTCATTTTCTACAAGTATCTTGGGAGAAAACACTGGAATCTGGTTTT
GTTATTACACTTACTGATGGTCATTCAGCATGGACTGGGACAGTTTCTGAATCAGAGATT
TCCCAAGAAGCTGATGACATGGCAATGGAAAAAGGGAAATATGTTGGTGAACTGAGAAAA
GCATTGTTGTCAGGAGCAGGACCAGCTGATGTATACACGTTTAATTTTTCTAAAGAGTCT
TGTTATTTCTTCTTTGAGAAAAACCTGAAAGATGTCTCATTCAGACTTGGTTCCTTCAAC
CTAGAGAAAGTTGAAAACCCAGCTGAAGTCATTAGAGAACTTATTTGTTATTGCTTGGAC
ACCATTGCAGAAAATCAAGCCAAAAATGAGCACCTGCAGAAAGAAAATGAAAGGCTTCTG
AGAGATTGGAATGATGTTCAAGGACGATTTGAAAAATGTGTGAGTGCTAAGGAAGCTTTG
GAGACTGATCTTTATAAGCGGTTTATTCTGGTGTTGAATGAGAAGAAAACAAAAATCAGA
AGTTTGCATAATAAATTATTAAATGCAGCTCAAGAACGAGAAAAGGACATCAAACAAGAA
GGGGAAACTGCAATCTGTTCTGAAATGACTGCTGACCGAGATCCAGTCTATGATGAGAGT
ACTGATGAGGAAAGTGAAAACCAAACTGATCTCTCTGGGTTGGCTTCAGCTGCTGTAAGT
AAAGATGATTCCATTATTTCAAGTCTTGATGTCACTGATATTGCACCAAGTAGAAAAAGG
AGACAGCGAATGCAAAGAAATCTTGGGACAGAACCTAAAATGGCTCCTCAGGAGAATCAG
CTTCAAGAAAAGGAAAATTCTAGGCCTGATTCTTCACTACCTGAGACGTCTAAAAAGGAG
CACATCTCAGCTGAAAACATGTCTTTAGAAACTCTGAGAAACAGCAGCCCAGAAGACCTC
TTTGATGAGATTTAACAGTCTCAAAAAATACTTTGATGTTCACTAGACTATGTTTTCTAT
TCATTTCTTTAAAATGAAAAAGGAGAATTTCAAGTCAGCAGCCGCTATTACCGTATCTTA
CAATTTAATTACATACACAGTGAATTGAAACCATTGTGCAAAATGGATTACACATGTATA
CAAAGATACGATTTGATGATGACACTGGCACATTATTCTAAACTATTCATTCAGCATGCC
TATAATTACATAAATTGTATGAGACTTTTTGTTGCAAAGGACACATTTATCATATTCATT
CACACATATTATATGTGATAGCTGTCCAACATCCTGTCTGGGAAGATTTTGAAAACAGGA
CAAAGAAAACATCACTTTAAAATGTCTTCAGCTTTTTTTGAATAGACGTATTCAAACATA
TTCTGAACATTGATGTTTGAACATTTTAATTTGTGTGATGATGTAGAAAATATAATTTTA
GTTTGTACATAAACATTGTGAAAATCTGATAATAAAATTTTTGATACACTAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_022550 unedited
CCCGCGGTTCAGATTTTGTAATACGACTTCACTATAGGGCGGCCGCGCAATTCGCCATTA
CGGCCGGGGACCGCGAAGTAGATCACGGAGGGGTGGGATCCGGGAGTGGGGCTGCCTCTT
TAAATAACAAAAATCTGAGGTATTAAGAAATGGAGAGAAAAATAAGCAGAATCCACCTTG
TTTCTGAACCCAGTATAACTCATTTTCTACAAGTATCTTGGGAGAAAACACTGGAATCTG
GTTTTGTTATGACACTTACTGATGGTCATTCAGCATGGACTGGGACAGTTTCTGAATCAG
AGATTTCCCAAGAAGCTGATGACATGGCAATGGAAAAAGGGAAATATGTTGGTGAACTGA
GAAAAGCATTGTTGTCAGGAGCAGGACCAGCTGATGTATACACGTTTAATTTTTCTAAAG
AGTCTTGTTATTTCTTCTTTGAGAAAAACCTGAAAGATGTCTCATTCAGACTTGGTTCCT
TCAACCTAGAGAAAGTTGAAAACCCAGCTGAAGTCATTAGAGAACTTATTTGTTATTGCT
TGGACACCATTGCAGAAAATCAAGCCAAAAATGAGCACCTGCAGAAAGAAAATGAAAGGC
TTCTGAGAGATTGGAATGATGTTCAAGGACGATTTGAAAAATGTGTGAGTGCTAAGGAAG
CTTTGGAGACTGATCTTTATAAGCGGTTTATTCTGGTGTTGAATGAGAAGAANACAAAAT
CAGAAGTTTGCATAATAAATTATTAAATGCAGCTCAAGGACGAGGAAAAGACATCAAACA
AGAAGGGGAAACTGCAATCTGTTCTGAAATGACTGCTGACCGAGTCCAGTCTATGATGAG
AGTACTGATGAGGGAAGTGAAAACCAACTGATCTCTCTGGGGTGGCTTCAGCTGCTGTAA
GTAAGATAN
Restriction Sites Please inquire     
ACCN NM_022550
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_022550.1, NP_072044.1
RefSeq Size 1707 bp
RefSeq ORF 1005 bp
Locus ID 7518
Cytogenetics 5q14.2
Protein Families Druggable Genome
Protein Pathways Non-homologous end-joining
Gene Summary 'The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. [provided by RefSeq, Oct 2019]'
Transcript Variant: This variant (3) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (1).

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