alpha Sarcoglycan (SGCA) (NM_000023) Human Untagged Clone

CAT#: SC126128

SGCA (untagged)-Human sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SGCA
• Synonyms: 50DAG; adhalin; ADL; DAG2; DMDA2; LGMD2D; LGMDR3; SCARMD1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000023 edited
  CTCACCGGGCGGGCCAGGCCGGGCAGCCATGGCTGAGACACTCTTCTGGACTCCTCTCCT
  CGTGGTTCTCCTGGCAGGGCTGGGGGACACCGAGGCCCAGCAGACCACGCTACACCCACT
  TGTGGGCCGTGTCTTTGTGCACACCTTGGACCATGAGACGTTTCTGAGCCTTCCTGAGCA
  TGTCGCTGTCCCACCCGCTGTCCACATCACCTACCACGCCCACCTCCAGGGACACCCAGA
  CCTGCCCCGGTGGCTCCGCTACACCCAGCGCAGCCCCCACCACCCTGGCTTCCTCTACGG
  CTCTGCCACCCCAGAAGATCGTGGGCTCCAGGTCATTGAGGTCACAGCCTACAATCGGGA
  CAGCTTTGATACCACTCGGCAGAGGCTGGTGCTGGAGATTGGGGACCCAGAAGGCCCCCT
  GCTGCCATACCAAGCCGAGTTCCTGGTGCGCAGCCACGATGCGGAGGAGGTGCTGCCCTC
  AACACCTGCCAGCCGCTTCCTCTCAGCCTTGGGGGGACTCTGGGAGCCCGGAGAGCTTCA
  GCTGCTCAACGTCACCTCTGCCTTGGACCGTGGGGGCCGTGTCCCCCTTCCCATTGAGGG
  CCGAAAAGAAGGGGTATACATTAAGGTGGGTTCTGCCTCACCTTTTTCTACTTGCCTGAA
  GATGGTGGCATCCCCCGATAGCCACGCCCGCTGTGCCCAGGGCCAGCCTCCACTTCTGTC
  TTGCTACGACACCTTGGCACCCCACTTCCGCGTTGACTGGTGCAATGTGACCCTGGTGGA
  TAAGTCAGTGCCGGAGCCTGCAGATGAGGTGCCCACCCCAGGTGATGGGATCCTGGAGCA
  TGACCCGTTCTTCTGCCCACCCACTGAGGCCCCAGACCGTGACTTCTTGGTGGATGCTCT
  GGTCACCCTCCTGGTGCCCCTGCTGGTGGCCCTGCTTCTCACCTTGCTGCTGGCCTATGT
  CATGTGCTGCCGGCGGGAGGGAAGGCTGAAGAGAGACCTGGCTACCTCCGACATCCAGAT
  GGTCCACCACTGCACCATCCACGGGAACACAGAGGAGCTGCGGCAGATGGCGGCCAGCCG
  CGAGGTGCCCCGGCCACTCTCCACCCTGCCCATGTTCAATGTGCACACAGGTGAGCGGCT
  GCCTCCCCGCGTGGACAGCGCCCAGGTGCCCCTCATTCTGGACCAGCACTGACAGCCCAG
  CCAGTGGTTCCAGGTCCAGCCCTGACTTCATCCTCCCTTCTCTGTCCACACCACGAGTGG
  CACATCCCACCTGCTGATTCCAGCTCCTGGCCCTCCTGGAACCCAGGCTCTAAACAAGCA
  GGGAGAGGGGGTGGGGTGGGGTGAGAGTGTGTGGAGTAAGGACATTCAGAATAAATATCT
  GCTGCTCTGCTCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000023 unedited
  TGCGGTTCAGGATTTGTATACGACTCACTATAGGCGGACCGCGAATCAGATCTGGTACCG
  GTCCGGAATTCCCGGGATCTCACCGGGCGGGCCAGGCCGGGCAGCCATGGCTGAGACACT
  CTTCTGGACTCCTCTCCTCGTGGTTCTCCTGGCAGGGCTGGGGGACACCGAGGCCCAGCA
  GACCACGCTACACCCACTTGTGGGCCGTGTCTTTGTGCACACCTTGGACCATGAGACGTT
  TCTGAGCCTTCCTGAGCATGTCGCTGTCCCACCCGCTGTCCACATCACCTACCACGCCCA
  CCTCCAGGGACACCCAGACCTGCCCCGGTGGCTCCGCTACACCCAGCGCAGCCCCCACCA
  CCCTGGCTTCCTCTACGGCTCTGCCACCCCAGAAGATCGTGGGCTCCAGGTCATTGAGGT
  CACAGCCTACAATCGGGACAGCTTTGATACCACTCGGCAGAGGCTGGTGCTGGAGATTGG
  GGACCCAGAAGGCCCCCTGCTGCCATACCAAGCCGAGTTCCTGGTGCGCAGCCACGATGC
  GGAGGAGGTGCTGCCCTCAACACCTGCCAGCCGCTTCCTCTCAGCCTTGGGGGGACTCTG
  GGAGCCCGGAGAGCTTCAGCTGCTCAACGTCACCTCTGCCTTGGACCGTGGGGGCCGTGT
  CCCCCTTCCCATTGAGGGCCGAAAAGAAGGGGTATACATTAAGGTGGGTTCTGCCTCACC
  TTTTTCTACTTGCCTGAAGATGGTGGCATCCCCCGATAGCCACGCCCGCTGTGCCCAGGG
  CCAGCCTCCACTTCTGTCTTGCTACGACACTTTGGCACCCCACTTCGCGTTGACTGGTGC
  AATGTGACCCTGGTTNATAAGTCAGTGCCGAGCCTGCAGATGAGTGCCCCACCCAGTGT
  
• Restriction Sites: Please inquire
• ACCN: NM_000023
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000023.1, NP_000014.1
• RefSeq Size: 1404 bp
• RefSeq ORF: 1164 bp
• Locus ID: 6442
• Cytogenetics: 17q21.33
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis
• Gene Summary: 'This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).