RUNX3 (BC013362) Human Untagged Clone

CAT#: SC126157

RUNX3 (untagged)-Human runt-related transcription factor 3, transcript variant 1 (cDNA clone MGC:16070 IMAGE:3615873), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RUNX3
• Synonyms: acute myeloid leukemia gene 2; AML2; CBFA3; core-binding factor, runt domain, alpha subunit 3; FLJ34510; MGC16070; OTTHUMP00000003370; OTTHUMP00000003371; PEA2 alpha C; PEBP2 alpha C; PEBP2aC; polyomavirus enhancer-binding protein 2 alpha C subunit; trans
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC013362 edited
  GGCGGCCCACTCTGCTCTGTCAGCTTCGGAGCTCCTCCACCCTGGCTGCCGAAAGCCCCT
  TCCCGCCATCTAATGATACACTCTGCATACGCTTCTGTTGAGAATTTGTGGCTAGACATT
  CCTGTGGGACCGGGAATCCAAATTCTTGGTAGCTAGAGGAAAAAAAAATAAAACAACAGC
  CAACCAAGTGAATCCCAACCCAACCCCCTGAAGGGCTGAAAATTCTCGCCTTCTTCAGAG
  CGGGGCATGGCATCGAACAGCATCTTCGACTCCTTCCCGACCTACTCGCCGACCTTCATC
  CGCGACCCAAGCACCAGCCGCCGCTTCACACCTCCCTCCCCGGCCTTCCCCTGCGGCGGC
  GGCGGCGGCAAGATGGGCGAGAACAGCGGCGCGCTGAGCGCGCAGGCGGCCGTGGGGCCC
  GGAGGGCGCGCCCGGCCCGAGGTGCGCTCGATGGTGGACGTGCTGGCGGACCACGCAGGC
  GAGCTCGTGCGCACCGACAGCCCCAACTTCCTCTGCTCCGTGCTGCCCTCGCACTGGCGC
  TGCAACAAGACGCTGCCCGTCGCCTTCAAGGTGGTGGCATTGGGGGACGTGCCGGATGGT
  ACGGTGGTGACTGTGATGGCAGGCAATGACGAGAACTACTCCGCTGAGCTGCGCAATGCC
  TCGGCCGTCATGAAGAACCAGGTGGCCAGGTTCAACGACCTTCGCTTCGTGGGCCGCAGT
  GGGCGAGGGAAGAGTTTCACCCTGACCATCACTGTGTTCACCAACCCCACCCAAGTGGCG
  ACCTACCACCGAGCCATCAAGGTGACCGTGGACGGACCCCGGGAGCCCAGACGGCACCGG
  CAGAAGCTGGAGGACCAGACCAAGCCGTTCCCTGACCGCTTTGGGGACCTGGAACGGCTG
  CGCATGCGGGTGACACCGAGCACACCCAGCCCCCGAGGCTCACTCAGCACCACAAGCCAC
  TTCAGCAGCCAGCCCCAGACCCCAATCCAAGGCACCTCGGAACTGAACCCATTCTCCGAC
  CCCCGCCAGTTTGACCGCTCCTTCCCCACGCTGCCAACCCTCACGGAGAGCCGCTTCCCA
  GACCCCAGGATGCATTATCCCGGGGCCATGTCAGCTGCCTTCCCCTACAGCGCCACGCCC
  TCGGGCACGAGCATCAGCAGCCTCAGCGTGGCGGGCATGCCGGCCACCAGCCGCTTCCAC
  CATACCTACCTCCCGCCACCCTACCCGGGGGCCCCGCAGAACCAGAGCGGGCCCTTCCAG
  GCCAACCCGTCCCCCTACCACCTCTACTACGGGACATCCTCTGGCTCCTACCAGTTCTCC
  ATGGTGGCCGGCAGCAGCAGTGGGGGCGACCGCTCACCTACCCGCATGCTGGCCTCTTGC
  ACCAGCAGCGCTGCCTCTGTCGCCGCCGGCAACCTCATGAACCCCAGCCTGGGCGGCCAG
  AGTGATGGCGTGGAGGCCGACGGCAGCCACAGCAACTCACCCACGGCCCTGAGCACGCCA
  GGCCGCATGGATGAGGCCGTGTGGCGGCCCTACTGACCGCCCTGGTGGACTCCTCCCGCT
  GGAGGCGGGGACCCTAACAACCTTCAAGACCAGTGATGGGCCGGCTCCGAGGCTCCGGGC
  GGGAATGGGACCTGCGCTCCAGGGTGGTCTCGGTCCCAGGGTGGTCCCAGCTGGTGGGAG
  CCTCTGGCTGCATCTGTGCAGCCACATCCTTGTACAGAGGCATAGGTTACCACCCCCACC
  CCGGCCCGGGATACTGCCCCCGGCCCAGATCCTGGCCGTCTCATCCCATACTTCTGTGGG
  GAATCAGCCTCCTGCCACCCCCCCGGAAGGACCTCACTGTCTCCAGCTATGCCCAGTGCT
  GCATGGGACCCATGTCTCCTGGGACAGAGGCCATCTCTCTTCCAGAGAGAGGCAGCATTG
  GCCCACAGGATAAGCCTCAGGCCCTGGGAAACCTCCCGACCCCTGCACCTTCGTTGGAGC
  CCCTGCATCCCCTGGGTCCAGCCCCCTCTGCATTTACACAGATTTGAGTCAGAACTGGAA
  AGTGTCCCCCACCCCCACCACCCTCGAGCGGGGTTCCCCTCATTGTACAGATGGGGCAGG
  ACCCAGCACGCTGCTGGCAGAGATGGTTTGAGAACACATCCAAGCCAGTCCCCCCAGCCC
  AGCTTCCCCTCCGTTCCTAACTGTTGGCTTTCCCCCAGCCGCACGGGTCCCAGGCCCCAG
  AGAAGATGAGTCTATGGCATCAGGTTCTTAAACCCAGGAAAGCACCTACAGACCGGCTCC
  TCCATGCACTTTACCAGCTCAACGCATCCACTCTCTGTTCTCTTGGCAGGGCGGGGGAGG
  GGGGATAGGAGGTCCCCTTTCCCCTAGGTGGTCTCATAATTCCATTTGTGGAGAGAACAG
  GAGGGCCAGATAGATAGGTCCTAGCAGAAGGCATTGAGGTGAGGGATCATTTTGGGTCAG
  ACATCAATGTCCCTGTCCCCCCTGGGTCCAGCCAAGCTGTGCCCCATCCCCCAAGCCTCC
  TGGGAGGATCCAGCCAAATCTTGCGACTCCTGGCACACACCTGTCTGTAACCTGTTTTGT
  GCTCTGAAAGCAAATAGTCCTGAGCAAAAAAAACAAAAAAAACAAAAAAAAAAAAAAAAA
  A
  
• Restriction Sites: Please inquire
• ACCN: BC013362
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC013362.2, AAH13362.1
• RefSeq Size: 2641 bp
• Locus ID: 864
• Cytogenetics: 1p36.11
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]'