ADCY6 (NM_015270) Human Untagged Clone

CAT#: SC126190

ADCY6 (untagged)-Human adenylate cyclase 6 (ADCY6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADCY6
• Synonyms: AC6; LCCS8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015270 edited
  CCGGGGTAGAGGGCGGCTGCGCTGGACAGCTCGGGAGGGGGCGAGGGCCGGGCGGACGGC
  GGACGGCGGACGGCGGGCGGGAGCCCAGGGCAGGCGCGGAGCCGGGCCGGCAGCAACATG
  TCATGGTTTAGTGGCCTCCTGGTCCCTAAAGTGGATGAACGGAAAACAGCCTGGGGTGAA
  CGCAATGGGCAGAAGCGTTCGCGGCGCCGTGGCACTCGGGCAGGTGGCTTCTGCACGCCC
  CGCTATATGAGCTGCCTCCGGGATGCAGAGCCACCCAGCCCCACCCCTGCGGGCCCCCCT
  CGGTGCCCCTGGCAGGATGACGCCTTCATCCGGAGGGGCGGCCCAGGCAAGGGCAAGGAG
  CTGGGGCTGCGGGCAGTGGCCCTGGGCTTCGAGGATACCGAGGTGACAACGACAGCGGGC
  GGGACGGCTGAGGTGGCGCCCGACGCGGTGCCCAGGAGTGGGCGATCCTGCTGGCGCCGT
  CTGGTGCAGGTGTTCCAGTCGAAGCAGTTCCGTTCGGCCAAGCTGGAGCGCCTGTACCAG
  CGGTACTTCTTCCAGATGAACCAGAGCAGCCTGACGCTGCTGATGGCGGTGCTGGTGCTG
  CTCACAGCGGTGCTGCTGGCTTTCCACGCCGCACCCGCCCGCCCTCAGCCTGCCTATGTG
  GCACTGTTGGCCTGTGCCGCCGCCCTGTTCGTGGGGCTCATGGTGGTGTGTAACCGGCAT
  AGCTTCCGCCAGGACTCCATGTGGGTGGTGAGTTACGTGGTGCTGGGCATCCTGGCGGCA
  GTGCAGGTCGGGGGCGCTCTCGCAGCAGACCCGCGCAGCCCCTCTGCGGGCCTCTGGTGC
  CCTGTGTTCTTTGTCTACATCGCCTACACGCTCCTCCCCATCCGCATGCGGGCTGCCGTC
  CTCAGCGGCCTGGGCCTCTCCACCTTGCATTTGATCTTGGCCTGGCAACTTAACCGTGGT
  GATGCCTTCCTCTGGAAGCAGCTCGGTGCCAATGTGCTGCTGTTCCTCTGCACCAACGTC
  ATTGGCATCTGCACACACTATCCAGCAGAGGTGTCTCAGCGCCAGGCCTTTCAGGAGACC
  CGCGGTTACATCCAGGCCCGGCTCCACCTGCAGCATGAGAATCGGCAGCAGGAGCGGCTG
  CTGCTGTCGGTATTGCCCCAGCACGTTGCCATGGAGATGAAAGAAGACATCAACACAAAA
  AAAGAAGACATGATGTTCCACAAGATCTACATACAGAAGCATGACAATGTCAGCATCCTG
  TTTGCAGACATTGAGGGCTTCACCAGCCTGGCATCCCAGTGCACTGCGCAGGAGCTGGTC
  ATGACCCTGAATGAGCTCTTTGCCCGGTTTGACAAGCTGGCTGCGGAGAATCACTGCCTG
  AGGATCAAGATCTTGGGGGACTGTTACTACTGTGTGTCAGGGCTGCCGGAGGCCCGGGCC
  GACCATGCCCACTGCTGTGTGGAGATGGGGGTAGACATGATTGAGGCCATCTCGCTGGTA
  CGTGAGGTGACAGGTGTGAATGTGAACATGCGCGTGGGCATCCACAGCGGGCGCGTGCAC
  TGCGGCGTCCTTGGCTTGCGGAAATGGCAGTTCGATGTGTGGTCCAATGATGTGACCCTG
  GCCAACCACATGGAGGCAGGAGGCCGGGCTGGCCGCATCCACATCACTCGGGCAACACTG
  CAGTACCTGAACGGGGACTACGAGGTGGAGCCAGGCCGTGGTGGCGAGCGCAACGCGTAC
  CTCAAGGAGCAGCACATTGAGACTTTCCTCATCCTGGGCGCCAGCCAGAAACGGAAAGAG
  GAGAAGGCCATGCTGGCCAAGCTGCAGCGGACTCGGGCCAACTCCATGGAAGGGCTGATG
  CCGCGCTGGGTTCCTGATCGTGCCTTCTCCCGGACCAAGGACTCCAAGGCCTTCCGCCAG
  ATGGGCATTGATGATTCCAGCAAAGACAACCGGGGCACCCAAGATGCCCTGAACCCTGAG
  GATGAGGTGGATGAGTTCCTGAGCCGTGCCATCGATGCCCGCAGCATTGATCAGCTGCGG
  AAGGACCATGTGCGCCGGTTTCTGCTCACCTTCCAGAGAGAGGATCTTGAGAAGAAGTAC
  TCCCGGAAGGTGGATCCCCGCTTCGGAGCCTACGTTGCCTGTGCCCTGTTGGTCTTCTGC
  TTCATCTGCTTCATCCAGCTTCTCATCTTCCCACACTCCACCCTGATGCTTGGGATCTAT
  GCCAGCATCTTCCTGCTGCTGCTAATCACCGTGCTGATCTGTGCTGTGTACTCCTGTGGT
  TCTCTGTTCCCTAAGGCCCTGCAACGTCTGTCCCGCAGCATTGTCCGCTCACGGGCACAT
  AGCACCGCAGTTGGCATCTTTTCCGTCCTGCTTGTGTTTACTTCTGCCATTGCCAACATG
  TTCACCTGTAACCACACCCCCATACGGAGCTGTGCAGCCCGGATGCTGAATTTAACACCT
  GCTGACATCACTGCCTGCCACCTGCAGCAGCTCAATTACTCTCTGGGCCTGGATGCTCCC
  CTGTGTGAGGGCACCATGCCCACCTGCAGCTTTCCTGAGTACTTCATCGGGAACATGCTG
  CTGAGTCTCTTGGCCAGCTCTGTCTTCCTGCACATCAGCAGCATCGGGAAGTTGGCCATG
  ATCTTTGTCTTGGGGCTCATCTATTTGGTGCTGCTTCTGCTGGGTCCCCCAGCCACCATC
  TTTGACAACTATGACCTACTGCTTGGCGTCCATGGCTTGGCTTCTTCCAATGAGACCTTT
  GATGGGCTGGACTGTCCAGCTGCAGGGAGGGTGGCCCTCAAATATATGACCCCTGTGATT
  CTGCTGGTGTTTGCGCTGGCGCTGTATCTGCATGCTCAGCAGGTGGAGTCGACTGCCCGC
  CTAGACTTCCTCTGGAAACTACAGGCAACAGGGGAGAAGGAGGAGATGGAGGAGCTACAG
  GCATACAACCGGAGGCTGCTGCATAACATTCTGCCCAAGGACGTGGCGGCCCACTTCCTG
  GCCCGGGAGCGCCGCAATGATGAACTCTACTATCAGTCGTGTGAGTGTGTGGCTGTTATG
  TTTGCCTCCATTGCCAACTTCTCTGAGTTCTATGTGGAGCTGGAGGCAAACAATGAGGGT
  GTCGAGTGCCTGCGGCTGCTCAACGAGATCATCGCTGACTTTGATGAGATTATCAGCGAG
  GAGCGGTTCCGGCAGCTGGAAAAGATCAAGACGATTGGTAGCACCTACATGGCTGCCTCA
  GGGCTGAACGCCAGCACCTACGATCAGGTGGGCCGCTCCCACATCACTGCCCTGGCTGAC
  TACGCCATGCGGCTCATGGAGCAGATGAAGCACATCAATGAGCACTCCTTCAACAATTTC
  CAGATGAAGATTGGGCTGAACATGGGCCCAGTCGTGGCAGGTGTCATCGGGGCTCGGAAG
  CCACAGTATGACATCTGGGGGAACACAGTGAATGTCTCTAGTCGTATGGACAGCACGGGG
  GTCCCCGACCGAATCCAGGTGACCACGGACCTGTACCAGGTTCTAGCTGCCAAGGGCTAC
  CAGCTGGAGTGTCGAGGGGTGGTCAAGGTGAAGGGCAAGGGGGAGATGACCACCTACTTC
  CTCAATGGGGGCCCCAGCAGTTAACAGGGCCCAGCCACAAATTCAGCTGAAGGGACCAAG
  GTGGGCATTGAGTGGACTCTGTGCTCACTGGGTGGAGCTGTGGCAGGGGGCACTGAGCCT
  CCAGACCCTGCTAACCACAAAAGGGAACATCCCAGCAGGCTGTGCTTGGATCATGCTCGT
  CTGCCCTCAAGCTGGAAAACAAGGGGCTACCTACCGAGAGGATTATGCAAGTGACTTTCT
  TTCTTACTTGGGGTAGGGCTGTTCCCTCTCCAATCTTCCAGCCTTTGGGAGCAGGGGAGG
  GGTCAGTAGCAGAAGCAGAGGGAGGCCTCTTGCCTGAGGGATTAAAATGGCAGCTTGCCA
  TGCCTACCCTTCCCTGTCTGTCTGGGCAGCAGGTTCAGGGCTGAGCCCTTCTTTTCCCTC
  TTTTTTCCTGGGAATATTTTGTACAATATTTTGTACAAAGACAGGCATGAGGAGTGCCTA
  TTCCATGCTTGCCTTTGCAATACCTGCATCCCCAGCACTGGTCCTGGGCACTTCCCCACC
  CCAGCCAGGTGTCCCTCCTATGCACAGAGCAGAGGAGGGAGAAGCTCTGGGGAGCCAGCT
  TTGGCCATATTTCAGGAGAATGTTTCCATGTGCCAAATCTTAGTCCCATGATCTGTCCCC
  AAAGGGGAACAAAGGGACCTCTGACAGCTTAGATTTAGCCCCAGTTCCTGCACGCTCCAG
  GGAACGGGGTGTCTGGCCTCACTGGTACTGTGAAAAATGCTCAGAGAGCAAGCCTGTGTG
  TGGGGATGTCAGGTCAGGAGCTGGAAGTTCACCTGCAGGTGCCAAAGAGCAGGCCGGCCA
  GGGCTGGGGCAGTGCCAGACTCTGATCTGAGGACCCCGTCGGGGTCCAGATCAGGTCACT
  CTGCCCCAGTGCTCTCTTGCTGTCTGCTGACAAGGGGGCATGGAGCATCTCTTCCTCTTC
  TGTTGCCAAATAGAAAAGGGTCAGGGCATGGAGAAAGGTGACCCTGATCCCAAACCTGCC
  CTCCCAAGTCTCTGGTGTTGGGGAGGGCCCGTGTGTTTGTGTAACTGTGTGTGCATGTTG
  GTCTTTGTGTGCATATCTGTTTTCCAGGTCTATGTGAGTCCTTGTGCTCCTGCTCCTCAG
  CTCTCCACCCCAGGTTGCCTCTCTCCTGTGGGCCTCTGTCTTCTGGGAATAAAGCAGGGT
  TTCCTACTTCAGGGGATGTAGAGAGATGCCCAGGTTGCACAGGAGTGGGATGGGGTGTGG
  TAGCAAAAGGAGGGAGAGGAGTCCTTTTTGTGCCAAATCCCTAAGTGCCGTTCGGGGGCC
  ATGTGTGCAGCATGACTCTCCCTGTCTGTGGCAGGGACCCAAGCGCTTGCTTAAGCCCCA
  GTGCTCCATGCCAGCACTTGAACTGTCTGGGGTTTGATGGACAGAGGCTGAGGAATTTCC
  TGGCTTCCCCAGATAGTGTCCTGGGACATGGTATGCTTTGGGGCTGGGGTAGCATGGAAT
  CCCTCTGAGGACCTGGATACTGGTACTACGGGGTGGGGAAGAGGAACCTTAAACTTGGCT
  TTCCCCAGCCTTCAGCCTGAGTCTAGCATGTTTCTAGCTCCCCAGTCCCTTGTGAAGCCT
  TGAGGGCTGGCAGAAGGGTTAGGAGGTTGAACTCTAGATTCCCTTCCTGTCTTTGCCTTC
  CTTTTACCCCTTTCCCTGCAACCTCCTTGACTCTGGCCTGAATTTGTTGGTGCCTCAGTT
  TCTCTGTCTGTACCTATTTAAGCCAAAGGCACTAGCCTGAATTTTGCTTGAAGATCACTT
  TGTCTTGGAAATGACTAGAGAGGCAGAGGAGAAGGGTTTCCAGAGTTGCTAGGTTTGGGA
  GTGGAAGGGGCAGGCAGTGCACTTGCCCCTCCTCATGCCCCTTCTGACACCAGCTCCCTG
  TGGAGGCCTGGTTTCTGGGTAATGCCTCCCTTGGGCATCTTCATGCATCAACCAAATGGG
  CCATCAGGTACTTCATTAGTCATGGCAGAAGGAGGGGAAAAGACTTGTTTTCCAGACAGA
  AAATCTACTCCCCTGTCCCCAGCCATATCCCTGGATAGGAAGGGATAGGAAGAGACTACT
  TGGTGCCATGGGGTAGGGGTGAGGGTATAAGTAGATCAGAGTGGGAAGACCTCAGCCTTG
  GGTGGCTTGTCTCTGCTTCTTGCCAGGTGGGAGGGCCTGTCCACACCCTGGATCCCCGTA
  CCACAGTGCCAGCCATGCCCTTCCCCTGGGCTACCATTGTCCCTTTCCTCACCCAGTTGG
  TAGAGGAGTCAGGAGGTGGGAGGCCGTGGGCTTTGGTTTTATAATGTAACCACTGTGGGG
  GTGGGGGAGGATGGTGAACCATGTATTTCAGTGAAATATTTAATATATTTAAATATCAAT
  AAAATCAAACTCTTTGTAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015270 unedited
  CCGGGTCGCCATTTGTAATACGACTTCACTATAGGGCGGCCGCGCATTCACATCTGGTAC
  CGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCCGGGGTAGAGGGCGGCTGC
  GCTGGACAGCTCGGGAGGGGGCGAGGGCCGGGCGGACGGCGGACGGCGGACGGCGGGCGG
  GAGCCCAGGGCAGGCGCGGAGCCGGGCCGGCAGCAACATGTCATGGTTTAGTGGCCTCCT
  GGTCCCTAAAGTGGATGAACGGAAAACAGCCTGGGGTGAACGCAATGGGCAGAAGCGTTC
  GCGGCGCCGTGGCACTCGGGCAGGTGGCTTCTGCACGCCCCGCTATATGAGCTGCCTCCG
  GGATGCAGAGCCACCCAGCCCCACCCCTGCGGGCCCCCCTCGGTGCCCCTGGCAGGATGA
  CGCCTTCATCCGGAGGGGCGGCCCAGGCAAGGGCAAGGAGCTGGGGCTGCGGGCAGTGGC
  CCTGGGCTTCGAGGATACCGAGGTGACAACGACAGCGGGCGGGACGGCTGAGGTGGCGCC
  CGACGCGGTGCCCAGGAGTGGGCGATCCTGCTGGCGCCGTCTGGTGCAGGTGTTCCAGTC
  GAAGCAGTTCCGTTCGGCCAAGCTGGAGCGCCTGTACCAGCGGTACTTCTTCCAGATGAA
  CCAGAGCAGCCTGACGCTGCTGATGGCGGTGCTGGTGCTGCTCACAGCGGTGCTGCTGGC
  TTTCCACGCCGCACCCGCCCGCCCTCAGCCTGCCTATGTGGCACTGTTGGCCTGTGCCGC
  CGCCCTNGGTCGTGGGCTCATGGTGGTGTGTAACCCGCATAGCTTCCGCCAGGACTCCAT
  GTGGGTGGTGAGTTACCTGGTGCTGGGCATCCTGGCNGCAGTGCAGGTCCGGGGCGCTCT
  CGCAGCAGACCCGCGCAGCCCCTA
  
• Restriction Sites: Please inquire
• ACCN: NM_015270
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015270.2, NP_056085.1
• RefSeq Size: 6594 bp
• RefSeq ORF: 3507 bp
• Locus ID: 112
• Cytogenetics: 12q13.12
• Domains: CYCc
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Dilated cardiomyopathy, Gap junction, GnRH signaling pathway, Melanogenesis, Oocyte meiosis, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction, Vascular smooth muscle contraction
• Gene Summary: 'This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015]'