MICB (BC044218) Human Untagged Clone

CAT#: SC126269

MICB (untagged)-Human MHC class I polypeptide-related sequence B (cDNA clone MGC:49933 IMAGE:6025253), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MICB
• Synonyms: MHC class I-like molecule PERB11.2-IMX; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I molecule; MHC class I polypeptide-r; OTTHUMP00000029089; OTTHUMP00000035091; OTTHUMP00000035588; PERB11.2; stress inducible class I homolog
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC044218 edited
  AGCGGTCGCTGAGCGGGGCGCAGGTGACTAAATTTCGACGGGGTCTTCTCACCGGTTTCA
  TTCAGTTGGCCACTGCTGAGCAGCTGAGAAGGTGGCGACGTAGGGGCCATGGGGCTGGGC
  CGGGTCCTGCTGTTTCTGGCCGTCGCCTTCCCTTTTGCACCCCCGGCAGCCGCCGCTGAG
  CCCCACAGTCTTCGTTACAACCTCATGGTGCTGTCCCAGGATGGATCTGTGCAGTCAGGG
  TTTCTCGCTGAGGGACATCTGGATGGTCAGCCCTTCCTGCGCTATGACAGGCAGAAACGC
  AGGGCAAAGCCCCAGGGACAGTGGGCAGAAGATGTCCTGGGAGCTGAGACCTGGGACACA
  GAGACCGAGGACTTGACAGAGAATGGGCAAGACCTCAGGAGGACCCTGACTCATATCAAG
  GACCAGAAAGGAGTGCCCCAGTCCTCCAGAGCTCAGACCTTGGCTATGAACGTCACAAAT
  TTCTGGAAGGAAGATGCCATGAAGACCAAGACACACTATCGCGCTATGCAGGCAGACTGC
  CTGCAGAAACTACAGCGATATCTGAAATCCGGGGTGGCCATCAGGAGAACAGTGCCCCCC
  ATGGTGAATGTCACCTGCAGCGAGGTCTCAGAGGGCAACATCACCGTGACATGCAGGGCT
  TCCAGCTTCTATCCCCGGAATATCACACTGACCTGGCGTCAGGATGGGGTATCTTTGAGC
  CACAACACCCAGCAGTGGGGGGATGTCCTGCCTGATGGGAATGGAACCTACCAGACCTGG
  GTGGCCACCAGGATTCGCCAAGGAGAGGAGCAGAGGTTCACCTGCTACATGGAACACAGC
  GGGAATCACGGCACTCACCCTGTGCCCTCTGGGAAGGCGCTGGTGCTTCAGAGTCAACGG
  ACAGACTTTCCATATGTTTCTGCTGCTATGCCATGTTTTGTTATTATTATTATTCTCTGT
  GTCCCTTGTTGCAAGAAGAAAACATCAGCGGCAGAGGGTCCAGAGCTTGTGAGCCTGCAG
  GTCCTGGATCAACACCCAGTTGGGACAGGAGACCACAGGGATGCAGCACAGCTGGGATTT
  CAGCCTCTGATGTCAGCTACTGGGTCCACTGGTTCCACTGAGGGCGCCTAGACTCTACAG
  CCAGGCGGCCAGGATTCAACTCCCTGCCTGGATCTCACCAGCACTTTCCCTCTGTTTCCT
  GACCTATGAAACAGAAAATAACATCACTTATTTATTGTTGTTGGATGCTGCAAAGTGTTA
  GTAGGTATGAGGTGTTTGCTGCTCTGCCACGTAGAGAGCCAGCAAAGGGATCATGACCAA
  CTCAACATTCCATTGGAGGCTATATGATCAAACAGCAAATTGTTTATCATGAATGCAGGA
  TGTGGGCAAACTCACGACTGCTCCTGCCAACAGAAGGTTTGCTGAGGGCATTCACTCCAT
  GGTGCTCATTGGAGTTATCTACTGGGTCATCTAGAGCCTATTGTTTGAGGAATGCAGTCT
  TACAAGCCTACTCTGGACCCAGCAGCTGACTCCTTCTTCCACCCCTCTTCTTGCTATCTC
  CTATACCAATAAATACGAAGGGCTGTGGAAGATCAGAGCCCTTGTTCACGAGAAGCAAGA
  AGCCCCCTGACCCCTTGTTCCAAATATACTCTTTTGTCTTTCTCTTTATTCCCACGTTCG
  CCCTTTGTTCAGTCCAATACAGGGTTGTGGGGCCCTTAACAGTGCCATATTAATTGGTAT
  CATTATTTCTGTTGTTTTTGTTTTTGTTTTTGTTTTTGTTTTTGAGACAGAGTCTCACTC
  TGTCACCCAGGCTGCAGTTCACTGGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCCAG
  GTTCAAGCACTTCTCGTACCTCAGACTCCCGAATAGCTGGGATTACAGACAGGCACCACC
  ACACCCAGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTCGCCAAGTTGACCAGCCCA
  GTTTCAAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCATCCCAAAGTGCTGGGATTA
  CAAGAATGAGCCACCGTGCCTGGCCTATTTTATTATATTGTAATATATTTTATTATATTA
  GCCACCATGCCTGTCCTATTTTCTTATGTTTTAATATATTTTAATATATTACATGTGCAG
  TAATTAGATTATCATGGGTGAACTTTATGAGTGAGTATCTTGGTGATGACTCCTCCTGAC
  CAGCCCAGGACCAGCTTTCTTGTCACCTTGAGGTCCCCTCGCCCCGTCACACCGTTATGC
  ATTACTCTGTGTCTACTATTATGTGTGCATAATTTATACCGTAAATGTTTTCTCTTTAAA
  TTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: BC044218
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC044218.1, AAH44218.1
• RefSeq Size: 2390 bp
• Locus ID: 4277
• Cytogenetics: 6p21.33
• Protein Families: Druggable Genome
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Gene Summary: 'This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]'