TCF7L1 (NM_031283) Human Untagged Clone

CAT#: SC126274

TCF7L1 (untagged)-Human transcription factor 7-like 1 (T-cell specific, HMG-box) (TCF7L1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TCF7L1
• Synonyms: TCF-3; TCF3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_031283 edited
  CCCACGCGTCCGGGGGAGCCCTAGGCTCGGCGCTGCCGGAGGGGCCCGAGCCGAGCCGCC
  TGCGCCCCGGCCGGGCAGCGCCGGGCCCGCTTCCCGCGGGGCCACGCCCTGTCAAACTTT
  GTTGCGGCGGCTAGCGCAGCGGGCCCGCAAGCGGGCGGGAGGGGCGCCGGGCCGGGCCGG
  GCAGGGCGCGGGCGGCTAGGGGCTCCGAGAGCGGCGGCCCCGGCCCGCGGCCCCACCATG
  CCCCAGCTCGGCGGCGGGGGCGGCGGCGGCGGCGGCAGCGGGGGAGGCGGCGGCTCCAGC
  GCCGGGGCGGCCGGCGGAGGGGACGACCTCGGGGCGAACGACGAGCTGATCCCCTTCCAG
  GACGAGGGGGGCGAGGAGCAGGAGCCGAGCAGCGATAGCGCCTCGGCGCAGCGGGACCTA
  GACGAGGTCAAGTCGTCCCTGGTCAACGAGTCGGAGAACCAGAGCAGCAGCTCGGACTCG
  GAGGCGGAGAGGCGCCCGCAGCCCGTCCGGGACACTTTCCAGAAGCCGCGGGACTATTTC
  GCCGAAGTGAGAAGGCCTCAGGACAGCGCGTTCTTTAAAGGACCCCCGTACCCTGGGTAC
  CCCTTCCTGATGATCCCGGACCTGAGCAGCCCGTACCTCTCCAACGGACCCCTGTCTCCC
  GGAGGAGCGCGCACCTACCTGCAGATGAAATGGCCCCTCCTCGATGTCCCCTCCAGCGCC
  ACAGTCAAGGACACGAGGTCACCATCTCCAGCACACTTGTCTAATAAAGTTCCTGTCGTT
  CAGCACCCGCATCACATGCATCCGCTGACTCCCCTCATCACCTACAGCAATGACCACTTC
  TCCCCCGGCTCCCCTCCCACCCACCTCTCCCCAGAGATCGATCCAAAGACAGGAATCCCC
  CGGCCCCCTCACCCATCCGAGCTGTCACCGTATTACCCACTCTCTCCCGGAGCTGTCGGA
  CAAATCCCCCACCCCCTCGGCTGGCTCGTCCCACAGCAAGGCCAGCCCATGTACTCCCTT
  CCTCCCGGTGGCTTCCGGCACCCTTACCCCGCCCTCGCCATGAACGCCTCGATGTCCAGC
  CTGGTCTCCAGTCGGTTCTCTCCTCACATGGTGGCTCCTGCCCACCCTGGCCTGCCCACC
  TCAGGGATCCCCCACCCTGCCATCGTCTCCCCCATCGTCAAGCAGGAACCGGCACCCCCC
  AGCCTGAGCCCTGCAGTGAGCGTGAAATCACCAGTCACCGTGAAAAAGGAGGAGGAAAAG
  AAGCCCCACGTGAAGAAGCCTCTGAATGCCTTCATGTTGTATATGAAGGAGATGAGGGCC
  AAGGTGGTGGCTGAGTGCACCCTGAAGGAAAGTGCAGCCATTAACCAGATCCTTGGAAGA
  AAGTGGCACAACCTGTCTCGAGAAGAACAGGCCAAGTACTACGAGCTGGCCCGGAAGGAG
  CGGCAGCTTCACTCGCAGCTCTACCCAACCTGGTCAGCCCGGGACAACTATGGTAAGAAA
  AAGAAGAGGAAGAGAGAAAAGCAGCTGTCCCAGACACAGTCACAGCAGCAAGTCCAGGAG
  GCAGAGGGTGCCCTGGCCTCCAAGAGCAAGAAGCCATGTGTTCAGTACCTGCCCCCCGAG
  AAGCCCTGTGACAGCCCTGCCTCCTCCCACGGGAGCATGCTGGACTCCCCGGCCACTCCC
  TCTGCAGCTTTGGCCTCACCAGCTGCCCCTGCTGCCACCCATTCGGAGCAAGCCCAGCCC
  CTCTCCCTCACCACCAAACCAGAAACCCGGGCCCAGCTGGCTCTCCACTCTGCCGCCTTC
  CTGTCGGCTAAGGCTGCAGCCTCCTCCTCTAGGCAGATGGGCAGCCAGCCTCCCCTCCTG
  TCCCGGCCCCTCCCCCTTGGGTCCATGCCCACAGCTCTGCTGGCCTCTCCCCCGTCCTTC
  CCCGCCACGCTCCATGCCCACCAGGCCCTCCCGGTGCTACAGGCCCAGCCTCTTTCCCTG
  GTCACCAAGTCTGCCCACTAAGCTCCCCCCGACCCCTGCAGGCTGTCACATGACTCATTG
  AGTAGTAATGATTCAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031283 unedited
  AGTATTTTGTCATACGACTCTACTATAGGGGCGGCCGCGTAATTCCCGGGTTATCGTCGA
  CCCACGTCGTCCGCCCACGCGTCCGGGGGAGCCCTAGGCTCGGCGCTGCCGGAGGGGCCC
  GAGCCGAGCCGCCTGCGCCCCGGCCGGGCAGCGCCGGGCCCGCTTCCCGCGGGGCCACGC
  CCTGTCAAACTTTGTTGCGGCGGCTAGCGCAGCGGGCCCGCAAGCGGGCGGGAGGGGCGC
  CGGGCCGGGCCGGGCAGGGCGCGGGCGGCTAGGGGCTCCGAGAGCGGCGGCCCCGGCCCG
  CGGCCCCACCATGCCCCATCTCGGCGGCGGGGGCGGCGGCGGCGGCGGCAGCGGGGGAGG
  CGGCGGCTCCAGCGCCGGGGCGGCCGGCGGAGGGGACGACCTCGGGGCGAACGACGAGCT
  GATCCCCTTCCAGGACGAGGGGGGCGAGGAGCAGGAGCCGAGCAGCGATAGCGCCTCGGC
  GCAGCGGGACCTAAACGAGGTCAAGTCGTCCCTGGTCAACGAGTCGGAGAACCAAGCAGC
  AGCTCGGACTCGGAAGCGGAGAGGCGCCCGCAGCCCGTCCGGAACACTTTCAAAAACCCC
  GGGACTATTTCCGCCAAATGAGAAGGCCTAAGAACGCGCGTTTTTTAAGGGACCCCGTTA
  CCCGGGGACCCCCTTCCGAGGATCCAGGACTTGACAGCCCGTAACTTTTTCAAAGGACCC
  CTGGTTTCCGGGAGGAGCCGCCCCTACCCTGGAAAGAAAAGGCCCTTTCCTGATTTCCCC
  CTCACCGCCCATGTCAGGAACCAAGGTCAACTTCTCAAGACAATTTGCAAAAAAAAAGCA
  TGGGGTGAAAAACCCATTCAGAGGGATCGGGTAGATCCCCTAATCCCTACAAAAGGGCCA
  ATTTTTCCCGGGAGGCATGATGACATACTTTTCGGGAATTCTGTCGAAAAGGGGAN
  
• Restriction Sites: Please inquire
• ACCN: NM_031283
• ORF Size: 1767 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_031283.1, NP_112573.1
• RefSeq Size: 2779
• RefSeq ORF: 1767
• Locus ID: 83439
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Melanogenesis, Pathways in cancer, Prostate cancer, Thyroid cancer, Wnt signaling pathway
• Gene Summary: This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]