COX4 (COX4I2) (NM_032609) Human Untagged Clone

CAT#: SC126284

COX4I2 (untagged)-Human cytochrome c oxidase subunit IV isoform 2 (lung) (COX4I2), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COX4I2
• Synonyms: COX4; COX4-2; COX4B; COX4L2; COXIV-2; dJ857M17.2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032609 edited
  CGTTGCTCGCTGGGCAGACCCAGGTCGCGCTCCCACTGCCGAGCCCGCGAGATGCTCCCC
  AGAGCTGCCTGGAGCTTGGTGCTGAGGAAAGGTGGAGGTGGAAGACGAGGGATGCACAGC
  TCAGAAGGCACCACCCGTGGTGGGGGGAAGATGTCCCCCTACACCAACTGCTATGCCCAG
  CGCTACTACCCCATGCCAGAAGAGCCCTTCTGCACAGAACTCAACGCTGAGGAGCAGGCC
  CTGAAGGAGAAGGAGAAGGGAAGCTGGACCCAGCTGACCCACGCCGAAAAGGTGGCCTTG
  TACCGGCTCCAGTTCAATGAGACCTTTGCGGAGATGAACCGTCGCTCCAATGAGTGGAAG
  ACAGTGATGGGTTGTGTCTTCTTCTTCATTGGATTCGCAGCTCTGGTGATTTGGTGGCAG
  CGGGTCTACGTATTTCCTCCAAAGCCGATCACCTTGACGGACGAGCGGAAAGCCCAGCAG
  CTGCAGCGCATGCTGGACATGAAGGTGAATCCTGTGCAGGGCCTGGCCTCCCGCTGGGAC
  TATGAGAAGAAGCAGTGGAAGAAGTGACTTGCATCCCCAGCTGTCTCCCTGAGGCTCCGC
  CCTGGCTGGGAGCCTCTGGCGGCCCCTCCCCTCCCCTGCCCTTAACCCCAGTAAAGCTCC
  AAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032609 unedited
  GGTTCTTATTTGTATACGACTACTATAGGCGGCCGCGTAATTCTCGAGCTCTAGCGAGGT
  GACAGCGTAGAACCAGCGTTGCTCGCTGGGCAGACCCAGGTCGCGCTCCCACTGCCGAGC
  CCGCGAGATGCTCCCCAGAGCTGCCTGGAGCTTGGTGCTGAGGAAAGGTGGAGGTGGAAG
  ACGAGGGATGCACAGCTCAGAAGGCACCACCCGTGGTGGGGGGAAGATGTCCCCCTACAC
  CAACTGCTATGCCCAGCGCTACTACCCCATGCCAGAAGAGCCCTTCTGCACAGAACTCAA
  CGCTGAGGAGCAGGCCCTGAAGGAGAAGGAGAAGGGAAGCTGGACCCAGCTGACCCACGC
  CGAAAAGGTGGCCTTGTACCGGCTCCAGTTCAATGAGACCTTTGCGGAGATGAACCGTCG
  CTCCAATGAGTGGAAGACAGTGATGGGTTGTGTCTTCTTCTTCATTGGATTCGCAGCTCT
  GGTGATTTGGTGGCAGCGGGTCTACGTATTTCCTCCAAAGCCGATCACCTTGACGGACGA
  GCGGAAAGCCCAGCAGCTGCAGCGCATGCTGGACATGAAGGTGAATCCTGTGCAGGGCCT
  GGCCTCCCGCTGGGACTATGAGAAGAAGCAGTGGAAGAAGTGACTTGCATCCCCAGCTGT
  CTCCCTGAGGCTCCGCCCTGGCTGGGAGCCTCTGGCGGCCCCTCCCCTCCCCTGCCCCTT
  ACCCCCAGTAAGCTCCCAAAAAAAAAAAAAAACTCTCCAGCGCTTGATCCCGCCATAAGG
  GCCTGATCCCTTCNAGGGGGGCCCGGTACCGATATCAAGCTTGTCGACTCTANTTGCGGC
  CGCGGTCATAGCTGTTTTCCTGACAGATCCCCGGTGGCATCCCTGTGACCCCCTCCCAGT
  GCCTCTTCTGGCCCTGGAAGTTGCCACTCCAGTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_032609
• ORF Size: 516 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_032609.2, NP_115998.2
• RefSeq Size: 684
• RefSeq ORF: 516
• Locus ID: 84701
• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]