TMEM158 (BC057390) Human Untagged Clone

CAT#: SC126320

TMEM158 (untagged)-Human Ras-induced senescence 1 (cDNA clone MGC:57838 IMAGE:6175193), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TMEM158
• Synonyms: BBP; BINP receptor; brain injury-derived neurotrophic peptide (BINP) binding protein; brain specific binding protein; DKFZp586E1621; p40BBP; Ras-induced senescence 1; Ras induced senescence 1; RIS1; transmembrane protein 158
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC057390 edited
  CGGCAGCCCAAGGGCCCCGGCGCCGGGGGCGGCGGGGAACCCCAAACGCAACCGGGTCTG
  GAGGGATCCCCGCGCCGAGCCAGCCGCCGTCACCGCCTCCGCGCCGCCCCTGCGGGCTTG
  GCAGGCGCCCGGCGCGCCCGCACTGCGCCCGGCCGCCGGCTCCCGCGGTCCCACCGTGAG
  CTCGCCGGCCCGTCGCCCGCTCGCCATGCAACCGCCGCCGGCCTCGCGCGCGTAGGCGCC
  CGCCGCAGGCCATGCTGCCCCTGCTCGCCGCGCTCCTGGCCGCCGCCTGCCCGCTGCCGC
  CCGTCCGCGGCGGGGCCGCGGACGCGCCCGGCCTCCTCGGGGTGCCCTCCAATGCTTCAG
  TCAACGCGTCCTCCGCGGACGAGCCCATCGCCCCGCGGCTGCTGGCCTCGGCGGCCCCCG
  GGCCCCCCGAGCGCCCGGGCCCGGAGGAGGCGGCGGCGGCGGCGGCGCCGTGCAACATCA
  GCGTGCAGCGGCAGATGCTGAGCTCGCTGCTCGTGCGCTGGGGCCGCCCGCGGGGCTTCC
  AGTGCGACCTACTGCTCTTCTCCACCAACGCGCACGGCCGCGCTTTCTTCGCCGCCGCCT
  TCCACCGCGTCGGGCCGCCGCTGCTCATCGAGCACCTGGGGCTGGCGGCGGGCGGCGCGC
  AGCAGGACCTGCGCCTCTGCGTGGGCTGCGGCTGGGTGCGCGGTCGCCGCACCGGCCGCC
  TCCGGCCCGCCGCCGCCCCCAGCGCCGCCGCCGCCACCGCCGGGGCGCCCACCGCGCTGC
  CAGCCTACCCCGCGGCCGAGCCGCCCGGGCCGCTGTGGCTGCAGGGCGAGCCGCTGCATT
  TCTGCTGCCTAGACTTCAGCCTGGAGGAGCTGCAGGGCGAGCCGGGCTGGCGGCTGAACC
  GTAAGCCCATTGAGTCCACGCTGGTGGCCTGCTTCATGACCCTGGTCATCGTGGTGTGGA
  GCGTGGCCGCCCTCATCTGGCCGGTGCCCATCATCGCCGGCTTCCTGCCCAACGGCATGG
  AACAGCGCCGGACCACCGCCAGCACCACCGCAGCCACCCCCGCCGCTGCCGCCGCCGCCG
  CGGCCGTCACTTCGGGGGTGGCGACCAAGTGACCCGCTCCGCTCCTCCCTGTGTCCGTCC
  TGTGTCCGCGCGCGCGGGTGCCTTTCCCGCCGGAGACTCGGCCGGTGTGCTTCGTGCTGT
  AGTTATCGTTAGTTCCTCTTCCCGAGATGGGGCCGCCGAGAGACCCCAGCGCCTTTGAAA
  AGCAAGGTTTGTGCTGCGCTTCCAGTTCCGAAAAGCAGATGTTTAAGCCCTTGGACTGAG
  GGTGGGATCGCAGCTCCGAAGACGGAGAGGAGGGAAATGGGGCCCTTTCCCCTCTATTGC
  ATCCCCCTGCCCGACTCCTTCCCCGCACCCACGTGCCCTAGATTCATGGCAGAAAATGAC
  CAAATCCTGTGTATTTGTTTTATATATTTAATAACTGTTTTAAATGAAAGTTTTAGTAAA
  AAAAATACAAAACAAAAAGATTAAATTGCTATTGCTGTAGTAAGAGAAGCTCTTTGTATC
  TGAACATAGTTGTATTTGAAATTTGTGGTTTTTTAATTTATTTAAAATTGGGGGGAGGGC
  ATGGGAAGGATTTAACACCGATATATTGTTACCGCTGAAAATGAACTTTATGAACCTTTT
  CCAAGTTGATCTATCCAGTGACGTGGCCTGGTGGGCGTTTCTTCTTGTACTTATGTGGTT
  TTTTGGCTTTTAATACAGACATTTTCCTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015444 unedited
  NGGCGTTGGATTTGTATACCACTATATAGGCGGCCGCGNAATTCAATCTGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGCGGCAGCCCAAGGCCCCGGCGCCGGG
  GGCGGCGGGGAACCCCAAACGCAACCGGGTCTGGAGGGATCCCCGCGCCGAGCCAGCCGC
  CGTCACCGCCTCCGCGCCGCCCCTGCGGGCTTGGCAGGCGCCCGGCGCGCCCGCACTGCG
  CCCGGCCGCCGGCTCCCGCGGTCCCACCGTGAGCTCGCCGGCCCGTCGCCCGCTCGCCAT
  GCAACCGCCGCCGGCCTCGCGCGCGTAGGCGCCCGCCGCAGGCCATGCTGCCCCTGCTCG
  CCGCGCTCCTGGCCGCCGCCTGCCCGCTGCCGCCCGTCCGCGGCGGGGCCGCGGACGCGC
  CCGGCCTCCTCGGGGTGCCCTCCAATGCTTCAGTCAACGCGTCCTCCGCGGACGAGCCCA
  TCGCCCCGCGGCTGCTGGCCTCGGCGGCCCCCGGGCCCCCCGAGCGCCCGGGCCCGGAGG
  AGGCGGCGGCGGCGGCGGCGCCGTGCAACATCAGCGTGCAGCGGCCAATGCTGAGCTCGC
  TGCTCGTGCGCTTGGGCCGCCCGCGGAGCTTCCGTGCGACCTACTGCTATTCTCAACAAC
  CGTGACGGGCGCGCTTTATTCCAAGCCGCCTTCCCCGAGACGGGCCGAAGCTGCTAATCA
  AGCACCTGGGGACGGGTGTACGAACATAACACACAATCAGCACACTCATAGTCAGCCTTT
  TCACCCCAGTCGACAAACCCCATAATTACAAAGGCTCGAAGCCAACCCTAAACCCCACGA
  CGTGCCCGACCCATACCGACCGCCAC
  
• Restriction Sites: NotI-NotI
• ACCN: BC057390
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC057390.1, AAH57390.1
• RefSeq Size: 1798
• Locus ID: 25907
• Protein Families: Druggable Genome
• Gene Summary: Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]