TOP1MT (NM_052963) Human Untagged Clone

CAT#: SC126339

TOP1MT (untagged)-Human topoisomerase (DNA) I, mitochondrial (TOP1MT), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TOP1MT
• Synonyms: 2900052H09Rik; mitochondrial topoisomerase I; topoisomerase (DNA) I, mitochondrial
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_052963 edited
  GGCAGATGCGCGTGGTGCGGCTGCTGCGGCTCCGGGCGGCTCTGACGCTGCTCGGGGAGG
  TCCCCCGCCGCCCGGCCTCCCGGGGTGTCCCGGGCTCGCGCAGGACGCAGAAGGGCAGTG
  GAGCCAGGTGGGAGAAGGAGAAGCACGAAGACGGGGTGAAGTGGAGACAGCTGGAGCACA
  AGGGCCCGTACTTCGCACCCCCATACGAGCCCCTTCCCGACGGAGTGCGTTTCTTCTATG
  AAGGAAGGCCTGTGAGATTGAGCGTGGCAGCGGAGGAGGTCGCCACTTTTTATGGGAGGA
  TGTTAGATCATGAATACACAACAAAGGAGGTTTTCCGGAAGAACTTCTTCAATGACTGGC
  GAAAGGAAATGGCGGTGGAAGAGAGGGAAGTCATCAAGAGCCTGGACAAGTGTGACTTCA
  CGGAGATCCACAGATACTTTGTGGACAAGGCCGCAGCCCGGAAAGTCCTGAGCAGGGAGG
  AGAAGCAGAAGCTAAAAGAAGAGGCAGAAAAACTTCAGCAAGAGTTCGGCTACTGTATTT
  TAGATGGTCACCAAGAAAAAATAGGCAACTTCAAGATTGAGCCGCCTGGCTTGTTCCGTG
  GCCGTGGCGACCATCCCAAGATGGGGATGCTGAAGAGAAGGATCACGCCAGAGGATGTGG
  TTATCAACTGCAGCAGGGACTCGAAGATCCCCGAGCCGCCGGCGGGGCACCAGTGGAAGG
  AGGTGCGCTCCGATAACACCGTCACGTGGCTGGCAGCTTGGACCGAGAGCATTCAGAACT
  CCATCAAGTACATCATGCTGAACCCTTGCTCGAAGCTGAAGGGGGAGACAGCTTGGCAGA
  AGTTTGAAACAGCTCGACGCCTGCGGGGATTTGTGGACGAGATCCGCTCCCAGTACCGGG
  CTGACTGGAAGTCTCGGGAAATGAAGACGAGACAGCGGGCGGTGGCCCTGTATTTCATCG
  ATAAGCTGGCACTGAGAGCAGGAAATGAGAAGGAGGACGGTGAGGCGGCCGACACCGTGG
  GCTGCTGTTCCCTCCGGGTGGAGCACGTCCAGCTGCACCCGGAGGCCGATGGCTGCCAAC
  ACGTGGTGGAATTTGACTTCCTGGGGAAGGACTGCATCCGCTACTACAACAGAGTGCCGG
  TGGAGAAGCCGGTGTACAAGAACTTACAGCTCTTTATGGAGAACAAGGACCCCCGGGACG
  ACCTCTTCGACAGGCTGACCACGACCAGCCTGAACAAGCACCTCCAGGAGCTGATGGACG
  GGCTGACGGCCAAGGTGTTCCGGACCTACAACGCCTCCATCACTCTGCAGGAGCAGCTGC
  GGGCCCTGACGCGCGCCGAGGACAGCATAGCAGCTAAGATCTTATCCTACAACCGAGCCA
  ACCGAGTCGTGGCCATTCTCTGCAACCATCAGCGAGCAACCCCCAGTACGTTCGAGAAGT
  CGATGCAGAATCTCCAGACGAAGATCCAGGCAAAGAAGGAGCAGGTGGCTGAGGCCAGGG
  CAGAGCTGAGGAGGGCGAGGGCTGAGCACAAAGCCCAAGGGGATGGCAAGTCCAGGAGTG
  TCCTGGAGAAGAAGAGGCGGCTCCTGGAGAAGCTGCAGGAGCAGCTGGCGCAGCTGAGTG
  TGCAGGCCACGGACAAGGAGGAGAACAAGCAGGTGGCCCTGGGCACGTCCAAGCTCAACT
  ACCTGGACCCCAGGATCAGCATTGCCTGGTGCAAGCGGTTCAGGGTGCCAGTGGAGAAGA
  TCTACAGCAAAACACAGCGGGAGAGGTTCGCCTGGGCTCTCGCCATGGCAGGAGAAGACT
  TTGAATTCTAACGACGAGCCGTGTTGAAACTTCTTTTGTATGTGTGTGTGTTTTTTTCAC
  TATTAAAGCAGTACTGGGGAATTTTGTACAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052963 unedited
  TTTAGTCAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGGCAGAT
  GCGCGTGGTGCGGCTGCTGCGGCTCCGGGCGGCTCTGACGCTGCTCGGGGAGGTCCCCCG
  CCGCCCGGCCTCCCGGGGTGTCCCGGGCTCGCGCAGGACGCAAAATGGCAGTGGAGCCAG
  GTGGGAGAAGGAGAAGCACGAATACGGGGTGAAGTGGAGACAGCTGGAGCACAAGGGCCC
  GTACTTCGCACCCCCATACGAGCCCCTTCCCGACGGAGTGCGTTTCTTCTATGAAGGAAG
  GCCTGTGAGATTGAGCGTGGCAACGGAGGAGGTCGCCACTTTTTATGGGAGGATGTTAGA
  TCATGAATACACAACAAAGGAGGTTTTCCGGAAGAACTTCTTCAATGACTGGCGAAAGGA
  AATGGCGGTGGAAGAGAGGGAAGTCATCAAGAGCCTGGACAAGTGTGACTTCACGGAGAT
  CCACAGATACTTTGTGGACAAGGCCGCAGCCCGGAAAGTCCTGAGCAGGGAGGAGAAGCA
  CAAGCTAAAAGAAGAGGCAGAAAAACTTCAGCAAGAGTTCGGCTACTGTATTTTAGATGG
  TCACCAAGAAAAAATAGGCAACTTCAAGATTGAGCCGCCTGGCTTGTTCCGTGGCCGTGG
  CGACCATCCCAAGATGGGGATGCTGAAGAGTAGGATCACGCCAGAGGATGTGGTTATCAA
  CTGCAGCAGGCACTCGAAGATCCCCGAGCCGCCGGCGGCGCACCACTGGAAGGGAGTGCG
  CTCCGATAACACCGTCACGTGGCTGGCAGCTTGGACCGAGAGCATTCAGGACTCCATCAA
  GTACATCATGCTGAACCCTTGCTCGAAGCTGAAGGGGGAGACAGCTTGGCANAAGTTTGA
  ACAGCTCGAGCC
  
• Restriction Sites: Please inquire
• ACCN: NM_052963
• ORF Size: 1806 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_052963.1, NP_443195.1
• RefSeq Size: 1923
• RefSeq ORF: 1806
• Locus ID: 116447
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (1) encodes the longer isoform (1).