LONP2 (NM_031490) Human Untagged Clone

CAT#: SC126500

LONP2 (untagged)-Human lon peptidase 2, peroxisomal (LONP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LONP2
• Synonyms: LONP; LONPL; PLON; PSLON
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126500 sequence for NM_031490 edited (data generated by NextGen Sequencing)
  ATGTCATCAGTGAGCCCCATCCAGATCCCCAGTCGCCTCCCGCTGCTGCTCACCCACGAG
  GGCGTCCTGCTGCCCGGCTCCACCATGCGCACCAGCGTGGACTCGGCCCGCAACCTGCAG
  CTGGTGCGGAGCCGCCTTCTGAAGGGCACGTCGCTGCAAAGCACCATCCTGGGCGTCATC
  CCCAACACGCCTGACCCCGCCAGCGACGCGCAGGACCTGCCGCCGCTGCACAGGATTGGC
  ACAGCTGCACTGGCCGTTCAGGTTGTGGGCAGTAACTGGCCCAAGCCCCACTACACTCTG
  TTGATTACAGGCCTATGCCGTTTCCAGATTGTACAGGTCTTAAAAGAGAAGCCATATCCC
  ATTGCTGAAGTGGAGCAGTTGGACCGACTTGAGGAGTTTCCCAACACCTGTAAAATGAGG
  GAGGAGCTAGGAGAACTATCAGAGCAGTTTTACAAATATGCAGTACAATTGGTTGAAATG
  TTGGATATGTCTGTCCCTGCAGTTGCTAAATTGAGACGTCTTTTAGATAGTCTTCCAAGG
  GAAGCTTTACCAGACATCTTGACATCAATTATCCGAACAAGCAACAAAGAGAAACTCCAG
  ATTTTAGATGCTGTGAGCCTAGAGGAGCGGTTCAAGATGACTATACCACTGCTTGTCAGA
  CAAATTGAAGGCCTGAAATTGCTTCAAAAAACCAGAAAACCCAAGCAAGATGATGATAAG
  AGGGTTATAGCAATACGCCCTATTAGGAGAATTACACATATCTCAGGTACTTTAGAAGAT
  GAAGATGAAGATGAAGATAATGATGACATTGTCATGCTAGAGAAAAAAATACGAACATCT
  AGTATGCCAGAGCAGGCCCATAAAGTCTGTGTCAAAGAGATAAAGAGACTCAAAAAAATG
  CCTCAGTCAATGCCAGAATATGCTCTGACTAGAAATTATTTGGAACTTATGGTAGAACTT
  CCTTGGAACAAAAGTACAACTGACCGCCTGGACATTAGGGCAGCCCGGATTCTTCTGGAT
  AATGACCATTACGCCATGGAAAAATTGAAGAAAAGAGTACTGGAATACTTGGCTGTCAGA
  CAGCTCAAAAATAACCTGAAGGGCCCAATCCTATGCTTTGTTGGCCCTCCTGGAGTTGGT
  AAAACAAGTGTGGGAAGATCAGTGGCCAAGACTCTAGGTCGAGAGTTCCACAGGATTGCA
  CTTGGAGGAGTATGTGATCAGTCTGACATTCGAGGACACAGGCGCACCTATGTTGGCAGC
  ATGCCTGGTCGCATCATCAACGGCTTGAAGACTGTGGGAGTGAACAACCCAGTGTTCCTA
  TTAGATGAGGTTGACAAACTGGGAAAAAGTCTACAGGGTGATCCAGCAGCAGCTCTGCTT
  GAGGTGTTGGATCCTGAACAAAACCATAACTTCACAGATCATTATCTAAATGTGGCCTTT
  GACCTTTCTCAAGTTCTTTTTATAGCTACTGCCAACACCACTGCTACCATTCCAGCTGCC
  TTGTTGGACAGAATGGAGATCATTCAGGTTCCAGGTTATACACAGGAGGAGAAGATAGAG
  ATTGCCCATAGGCACTTGATCCCCAAGCAGCTGGAACAACATGGGCTGACTCCACAGCAG
  ATTCAGATACCCCAGGTCACCACTCTTGACATCATCACCAGGTATACCAGAGAGGCAGGG
  GTTCGTTCTCTGGATAGAAAACTTGGGGCCATTTGCCGAGCTGTGGCCGTGAAGGTGGCA
  GAAGGACAGCATAAGGAAGCCAAGTTGGACCGTTCTGATGTGACTGAGAGAGAAGGTTGC
  AGAGAACACATCTTAGAAGATGAAAAACCTGAATCTATCAGTGACACTACTGACTTGGCT
  CTACCACCTGAAATGCCGATTTTGATTGATTTCCATGCTCTGAAAGACATCCTTGGGCCC
  CCGATGTATGAAATGGAGGTATCTCAGCGTTTGAGTCAGCCAGGAGTAGCAATAGGTTTG
  GCTTGGACTCCCTTAGGTGGAGAAATCATGTTCGTGGAGGCGAGTCGAATGGATGGCGAG
  GGCCAGTTAACTCTGACCGGCCAGCTCGGGGACGTGATGAAGGAGTCCGCCCACCTCGCT
  ATCAGCTGGCTCCGCAGCAACGCAAAGAAGTACCAGCTGACCAATGCTTTTGGAAGTTTT
  GATCTTCTTGACAACACAGACATCCATCTGCACTTCCCAGCTGGAGCTGTCACAAAAGAT
  GGACCATCTGCTGGAGTTACCATAGTAACCTGTCTCGCCTCACTTTTTAGTGGGCGGCTG
  GTACGTTCAGATGTAGCCATGACTGGAGAAATTACACTGAGAGGTCTTGTTCTTCCAGTG
  GGTGGAATTAAAGACAAAGTGCTGGCGGCACACAGAGCGGGACTGAAGCAAGTCATTATT
  CCTCGGAGAAATGAAAAAGACCTTGAGGGAATCCCAGGCAACGTACGACAGGATTTAAGT
  TTTGTCACAGCAAGCTGCCTGGATGAGGTTCTTAATGCAGCTTTTGATGGTGGCTTTACT
  GTCAAGACCAGACCTGGTCTGTTAAATAGCAAACTGTAG
  
  Clone variation with respect to NM_031490.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031490 unedited
  TTGAATCCGATTTCTATAGGCGGCCGCGCAATTCGCACGAGGGGGGTCTGAGGTTTGGTG
  ACTGCGGGGCAGGCCGGGGGCAGCTGTCTGTCTGGCTCTTTTTGACAGCCCCCAGTGCGA
  AAGGCTGCCAGCATGTCATCAGTGAGCCCCATCCAGATCCCCAGTCGCCTCCCGCTGCTG
  CTCACCCACGAGGGCGTCCTGCTGCCCGGCTCCACCATGCGCACCAGCGTGGACTCGGCC
  CGCAACCTGCAGCTGGTGCGGAGCCGCCTTCTGAAGGGCACGTCGCTGCAAAGCACCATC
  CTGGGCGTCATCCCCAACACGCCTGACCCCGCCAGCGACGCGCAGGACCTGCCGCCGCTG
  CACAGGATTGGCACAGCTGCACTGGCCGTTCAGGTTGTGGGCAGTAACTGGCCCAAGCCC
  CACTACACTCTGTTGATTACAGGCCTATGCCGTTTCCAGATTGTACAGGTCTTAAAAGAG
  AAGCCATATCCCATTGCTGAAGTGGAGCAGTTGGACCGACTTGAGGAGTTTCCCAACACC
  TGTAAAATGAGGGAGGAGCTAGGAGAACTATCAGAGCAGTTTTACAAATATGCAGTACAA
  TTGGTTGAAATGTTGGATATGTCTGTCCCTGCAGTTGCTAAATTGAGACGTCTTTTAGAT
  AGTCTTCCAAGGGAAGCTTTACCAGACATCTTGACATCAATTATCCGAACAAGCACANAG
  AGAAACTCCAGATTNTAGATGCTGTGAGCCTAGAGGAGCGGTTCAAGATGACTATACCAC
  TGCTTGTCAGACANNATGAAGGCCCTGAATTGCTTCAAAAACCAGAAACCCCAAGCAGAG
  ATGATAAGAAGGTTATAGCCATACGCCCTATTTAGAGAATACACTATCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_031490
• ORF Size: 2559 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_031490.2, NP_113678.2
• RefSeq Size: 4342
• RefSeq ORF: 2559
• Locus ID: 83752
• Domains: Lon_C, AAA, AAA
• Protein Families: Druggable Genome, Protease
• Gene Summary: In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
  Transcript Variant: This variant (1) represents the longest transcript and encodes isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.