C1S (NM_201442) Human Untagged Clone

CAT#: SC126504

C1S (untagged)-Human complement component 1, s subcomponent (C1S), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C1S
• Synonyms: EDSPD2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126504 sequence for NM_201442 edited (data generated by NextGen Sequencing)
  ATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATGCTGAGCCTACCATGTAT
  GGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTGAGGTAGAGAAATCTTGG
  GACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCACCCATCTGGACATTGAG
  CTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAGGAGACACTGAAGAAGGG
  AGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAATTGTGGAAGAGTTCCAA
  GTCCCATACAACAAACTCCAGGTGATCTTTAAGTCAGACTTTTCCAATGAAGAGCGTTTT
  ACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAATGCACAGATTTTGTAGAT
  GTCCCTTGTAGCCACTTCTGCAACAATTTCATTGGTGGTTACTTCTGCTCCTGCCCCCCG
  GAATATTTCCTCCATGATGACATGAAGAATTGCGGAGTTAATTGCAGTGGGGATGTATTC
  ACTGCACTGATTGGGGAGATTGCAAGTCCCAATTATCCCAAACCATATCCAGAGAACTCA
  AGGTGTGAATACCAGATCCGGTTGGAGAAAGGGTTCCAAGTGGTGGTGACCTTGCGGAGA
  GAAGATTTTGATGTGGAAGCAGCTGACTCAGCGGGAAACTGCCTTGACAGTTTAGTTTTT
  GTTGCAGGAGATCGGCAATTTGGTCCTTACTGTGGTCATGGATTCCCTGGGCCTCTAAAT
  ATTGAAACCAAGAGTAATGCTCTTGATATCATCTTCCAAACTGATCTAACAGGGCAAAAA
  AAGGGCTGGAAACTTCGCTATCATGGAGATCCAATGCCCTGCCCTAAGGAAGACACTCCC
  AATTCTGTTTGGGAGCCTGCGAAGGCAAAATATGTCTTTAGAGATGTGGTGCAGATAACC
  TGTCTGGATGGGTTTGAAGTTGTGGAGGGACGTGTTGGTGCAACATCTTTCTATTCGACT
  TGTCAAAGCAATGGAAAGTGGAGTAATTCCAAACTGAAATGTCAACCTGTGGACTGTGGC
  ATTCCTGAATCCATTGAGAATGGTAAAGTTGAAGACCCAGAGAGCACTTTGTTTGGTTCT
  GTCATCCGCTACACTTGTGAGGAGCCATATTACTACATGGAAAATGGAGGAGGTGGGGAG
  TATCACTGTGCTGGTAACGGGAGCTGGGTGAATGAGGTGCTGGGCCCGGAGCTGCCGAAA
  TGTGTTCCAGTCTGTGGAGTCCCCAGAGAACCCTTTGAAGAAAAACAGAGGATAATTGGA
  GGATCCGATGCAGATATTAAAAACTTCCCCTGGCAAGTCTTCTTTGACAACCCATGGGCT
  GGTGGAGCGCTCATTAATGAGTACTGGGTGCTGACGGCTGCTCATGTTGTGGAGGGAAAC
  AGGGAGCCAACAATGTATGTTGGGTCCACCTCAGTGCAGACCTCACGGCTGGCAAAATCC
  AAGATGCTCACTCCTGAGCATGTGTTTATTCATCCGGGATGGAAGCTGCTGGAAGTCCCA
  GAAGGACGAACCAATTTTGATAATGACATTGCACTGGTGCGGCTGAAAGACCCAGTGAAA
  ATGGGACCCACCGTCTCTCCCATCTGCCTACCAGGCACCTCTTCCGACTACAACCTCATG
  GATGGGGACCTGGGACTGATCTCAGGCTGGGGCCGAACAGAGAAGAGAGATCGTGCTGTT
  CGCCTCAAGGCGGCAAGGTTACCTGTAGCTCCTTTAAGAAAATGCAAAGAAGTGAAAGTG
  GAGAAACCCACAGCAGATGCAGAGGCCTATGTTTTCACTCCTAACATGATCTGTGCTGGA
  GGAGAGAAGGGCATGGATAGCTGTAAAGGGGACAGTGGTGGGGCCTTTGCTGTACAGGAT
  CCCAATGACAAGACCAAATTCTACGCAGCTGGCCTGGTGTCCTGGGGGCCCCAGTGTGGG
  ACCTATGGGCTCTACACACGGGTAAAGAACTATGTTGACTGGATAATGAAGACTATGCAG
  GAAAATAGCACCCCCCGTGAGGACTAA
  
  Clone variation with respect to NM_201442.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_201442 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCGGGTAGGGAATCT
  TATGAACAGAACCAGGACAGGGAGGCTGGCCGGAGGTTCCTGCAGAGGGAGCGTCAAGGC
  CCTGTGCTGCTGTCCCTGGGGGCCAGAGGGGTTGCCCAGCATGCCCACTGGCAGGAGAGA
  GGGAACTGACCCACTTGCTCCTACCAGCTTCTGAAGGTGACACTGAGCCCCAGGTGACGC
  CGCACCACCAAAGAAGGTGCTTGTGTTTGTCAGACAAATACAGCCAGGCCTGCCACCCCT
  TAGGCTCCAAAGTCCGGAGGTGCAGAAAGCCAGGACCAAGAGACAGGCAGCTCACCAGGG
  TGGACAAATCGCCAGAGATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATG
  CTGAGCCTACCATGTATGGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTG
  AGGTAGAGAAATCTTGGGACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCA
  CCCATCTGGACATTGAGCTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAG
  GAGACACTGAAGAANGGAGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAA
  TTGTGGAAGAGTTCCCAGTCCCATACCACANACTCCAGGTGATCTTTAAGTCAGACTTTT
  TCCATGAAGAGCGTTNTACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAAT
  GCACAGATTNNTGTAGATGTCCCCTTGTACCCCACTTCTGCACAATTTCATTGGTGGTTA
  CCTTCTGCTNCCGGCCCCCCGAATATTTCCTCCATGATGACATGAAGAATGGCCGGAGTA
  AATGCAGTGGGGATTGGATCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_201442 unedited
  CTATGGAACGCGGCACGCTTTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCTTATAAAC
  ATCCTTTATTGTACATAGACAGTGGATACTGAGAATGATCAAGTAAATGGAATTTTGAAC
  AGGTAAAGAGGAAACAAAGAATTAAGGTATCCCTGTGGAATAGTGCAAGAAAGGAGTGCC
  CCACCCATAGTGTTATCTACAATAGGTACTCCGGGGAAAGGACCCCAAGGAGTCAGACCA
  CAAATGTATGACCAGCACAATTCTATGATCAAACTCTACCTCTAGCAAGGCGTCTCAACA
  ATCAAGTTCTATTTAAATCATTCGCTCGTGTCTTCTTTCAGTCATGATGAAATAATGAGA
  ATATCATAAGGAACAGAAGGTAATGCATTGGTCACCACCCTTGGAGAGGCTGGTGGGATG
  TATCTGGATTAGTCCTCACGGGGGGTGCTATTTTCCTGCATAGTCTTCATTATCCAGTCA
  ACATAGTTCTTTACCCGTGTGTAGAGCCCATAGGTCCCACACTGGGGCCCCCAGGACACC
  AGGCCAGCTGCGTAGAATTTGGTCTTGTCATTGGGATCCTGTACAGCAAAGGCCCCACCA
  CTGTCCCCTTTACAGCTATCCATGCCCTTCTCTCCTCCAGCACAGATCATGTTAGGAGTG
  AAAACATAAGCCTCTGCATCTGCTGTGGGTTTCTCCACTTTCACTTCTTTGCATTTTCTT
  AAAGGAGCTACAGGTAACCTTGCCGCCTTGAAGCGAACAGCACGATCTCTCTTCTCTGTT
  CGGCCCCAGCCTGAGATCAGTCCCAGGTCCCATCCATGAGTTGTANTCGGAAAAAGTGCC
  TGTAAGCACATGGAAGATACGTGGGGTCCATTTTCACTGGGTCTTTCAGCCGCACCATGC
  AATGTCATATCAAAATGGNTCGTCCTTCGGGACTTCACAGCTTCCTCCCGGTGAATTACC
  ATGCTCAGGATGAGCTCTGGATTTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_201442
• Insert Size: 2900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201442.1, NP_958850.1
• RefSeq Size: 2813 bp
• RefSeq ORF: 2067 bp
• Locus ID: 716
• Cytogenetics: 12p13.31
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades, Systemic lupus erythematosus
• Gene Summary: 'This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1).