C1S (NM_201442) Human Untagged Clone

CAT#: SC126504

C1S (untagged)-Human complement component 1, s subcomponent (C1S), transcript variant 1


  "NM_201442" in other vectors (6)

Reconstitution Protocol

SC126504 is the updated version of SC127554.

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol C1S
Synonyms EDSPD2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC126504 sequence for NM_201442 edited (data generated by NextGen Sequencing)
ATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATGCTGAGCCTACCATGTAT
GGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTGAGGTAGAGAAATCTTGG
GACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCACCCATCTGGACATTGAG
CTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAGGAGACACTGAAGAAGGG
AGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAATTGTGGAAGAGTTCCAA
GTCCCATACAACAAACTCCAGGTGATCTTTAAGTCAGACTTTTCCAATGAAGAGCGTTTT
ACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAATGCACAGATTTTGTAGAT
GTCCCTTGTAGCCACTTCTGCAACAATTTCATTGGTGGTTACTTCTGCTCCTGCCCCCCG
GAATATTTCCTCCATGATGACATGAAGAATTGCGGAGTTAATTGCAGTGGGGATGTATTC
ACTGCACTGATTGGGGAGATTGCAAGTCCCAATTATCCCAAACCATATCCAGAGAACTCA
AGGTGTGAATACCAGATCCGGTTGGAGAAAGGGTTCCAAGTGGTGGTGACCTTGCGGAGA
GAAGATTTTGATGTGGAAGCAGCTGACTCAGCGGGAAACTGCCTTGACAGTTTAGTTTTT
GTTGCAGGAGATCGGCAATTTGGTCCTTACTGTGGTCATGGATTCCCTGGGCCTCTAAAT
ATTGAAACCAAGAGTAATGCTCTTGATATCATCTTCCAAACTGATCTAACAGGGCAAAAA
AAGGGCTGGAAACTTCGCTATCATGGAGATCCAATGCCCTGCCCTAAGGAAGACACTCCC
AATTCTGTTTGGGAGCCTGCGAAGGCAAAATATGTCTTTAGAGATGTGGTGCAGATAACC
TGTCTGGATGGGTTTGAAGTTGTGGAGGGACGTGTTGGTGCAACATCTTTCTATTCGACT
TGTCAAAGCAATGGAAAGTGGAGTAATTCCAAACTGAAATGTCAACCTGTGGACTGTGGC
ATTCCTGAATCCATTGAGAATGGTAAAGTTGAAGACCCAGAGAGCACTTTGTTTGGTTCT
GTCATCCGCTACACTTGTGAGGAGCCATATTACTACATGGAAAATGGAGGAGGTGGGGAG
TATCACTGTGCTGGTAACGGGAGCTGGGTGAATGAGGTGCTGGGCCCGGAGCTGCCGAAA
TGTGTTCCAGTCTGTGGAGTCCCCAGAGAACCCTTTGAAGAAAAACAGAGGATAATTGGA
GGATCCGATGCAGATATTAAAAACTTCCCCTGGCAAGTCTTCTTTGACAACCCATGGGCT
GGTGGAGCGCTCATTAATGAGTACTGGGTGCTGACGGCTGCTCATGTTGTGGAGGGAAAC
AGGGAGCCAACAATGTATGTTGGGTCCACCTCAGTGCAGACCTCACGGCTGGCAAAATCC
AAGATGCTCACTCCTGAGCATGTGTTTATTCATCCGGGATGGAAGCTGCTGGAAGTCCCA
GAAGGACGAACCAATTTTGATAATGACATTGCACTGGTGCGGCTGAAAGACCCAGTGAAA
ATGGGACCCACCGTCTCTCCCATCTGCCTACCAGGCACCTCTTCCGACTACAACCTCATG
GATGGGGACCTGGGACTGATCTCAGGCTGGGGCCGAACAGAGAAGAGAGATCGTGCTGTT
CGCCTCAAGGCGGCAAGGTTACCTGTAGCTCCTTTAAGAAAATGCAAAGAAGTGAAAGTG
GAGAAACCCACAGCAGATGCAGAGGCCTATGTTTTCACTCCTAACATGATCTGTGCTGGA
GGAGAGAAGGGCATGGATAGCTGTAAAGGGGACAGTGGTGGGGCCTTTGCTGTACAGGAT
CCCAATGACAAGACCAAATTCTACGCAGCTGGCCTGGTGTCCTGGGGGCCCCAGTGTGGG
ACCTATGGGCTCTACACACGGGTAAAGAACTATGTTGACTGGATAATGAAGACTATGCAG
GAAAATAGCACCCCCCGTGAGGACTAA

Clone variation with respect to NM_201442.2
>OriGene 5' read for NM_201442 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCGGGTAGGGAATCT
TATGAACAGAACCAGGACAGGGAGGCTGGCCGGAGGTTCCTGCAGAGGGAGCGTCAAGGC
CCTGTGCTGCTGTCCCTGGGGGCCAGAGGGGTTGCCCAGCATGCCCACTGGCAGGAGAGA
GGGAACTGACCCACTTGCTCCTACCAGCTTCTGAAGGTGACACTGAGCCCCAGGTGACGC
CGCACCACCAAAGAAGGTGCTTGTGTTTGTCAGACAAATACAGCCAGGCCTGCCACCCCT
TAGGCTCCAAAGTCCGGAGGTGCAGAAAGCCAGGACCAAGAGACAGGCAGCTCACCAGGG
TGGACAAATCGCCAGAGATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATG
CTGAGCCTACCATGTATGGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTG
AGGTAGAGAAATCTTGGGACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCA
CCCATCTGGACATTGAGCTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAG
GAGACACTGAAGAANGGAGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAA
TTGTGGAAGAGTTCCCAGTCCCATACCACANACTCCAGGTGATCTTTAAGTCAGACTTTT
TCCATGAAGAGCGTTNTACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAAT
GCACAGATTNNTGTAGATGTCCCCTTGTACCCCACTTCTGCACAATTTCATTGGTGGTTA
CCTTCTGCTNCCGGCCCCCCGAATATTTCCTCCATGATGACATGAAGAATGGCCGGAGTA
AATGCAGTGGGGATTGGATCAC
>OriGene 3' read for NM_201442 unedited
CTATGGAACGCGGCACGCTTTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCTTATAAAC
ATCCTTTATTGTACATAGACAGTGGATACTGAGAATGATCAAGTAAATGGAATTTTGAAC
AGGTAAAGAGGAAACAAAGAATTAAGGTATCCCTGTGGAATAGTGCAAGAAAGGAGTGCC
CCACCCATAGTGTTATCTACAATAGGTACTCCGGGGAAAGGACCCCAAGGAGTCAGACCA
CAAATGTATGACCAGCACAATTCTATGATCAAACTCTACCTCTAGCAAGGCGTCTCAACA
ATCAAGTTCTATTTAAATCATTCGCTCGTGTCTTCTTTCAGTCATGATGAAATAATGAGA
ATATCATAAGGAACAGAAGGTAATGCATTGGTCACCACCCTTGGAGAGGCTGGTGGGATG
TATCTGGATTAGTCCTCACGGGGGGTGCTATTTTCCTGCATAGTCTTCATTATCCAGTCA
ACATAGTTCTTTACCCGTGTGTAGAGCCCATAGGTCCCACACTGGGGCCCCCAGGACACC
AGGCCAGCTGCGTAGAATTTGGTCTTGTCATTGGGATCCTGTACAGCAAAGGCCCCACCA
CTGTCCCCTTTACAGCTATCCATGCCCTTCTCTCCTCCAGCACAGATCATGTTAGGAGTG
AAAACATAAGCCTCTGCATCTGCTGTGGGTTTCTCCACTTTCACTTCTTTGCATTTTCTT
AAAGGAGCTACAGGTAACCTTGCCGCCTTGAAGCGAACAGCACGATCTCTCTTCTCTGTT
CGGCCCCAGCCTGAGATCAGTCCCAGGTCCCATCCATGAGTTGTANTCGGAAAAAGTGCC
TGTAAGCACATGGAAGATACGTGGGGTCCATTTTCACTGGGTCTTTCAGCCGCACCATGC
AATGTCATATCAAAATGGNTCGTCCTTCGGGACTTCACAGCTTCCTCCCGGTGAATTACC
ATGCTCAGGATGAGCTCTGGATTTG
Restriction Sites NotI-NotI     
ACCN NM_201442
Insert Size 2900 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_201442.1, NP_958850.1
RefSeq Size 2813 bp
RefSeq ORF 2067 bp
Locus ID 716
Cytogenetics 12p13.31
Protein Families Druggable Genome, Protease
Protein Pathways Complement and coagulation cascades, Systemic lupus erythematosus
Gene Summary 'This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1).

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