cIAP1 (BIRC2) (NM_001166) Human Untagged Clone

CAT#: SC126567

BIRC2 (untagged)-Human baculoviral IAP repeat containing 2 (BIRC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BIRC2
• Synonyms: API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126567 sequence for NM_001166 edited (data generated by NextGen Sequencing)
  ATGCACAAAACTGCCTCCCAAAGACTTTTCCCAGGTCCCTCGTATCAAAACATTAAGAGT
  ATAATGGAAGATAGCACGATCTTGTCAGATTGGACAAACAGCAACAAACAAAAAATGAAG
  TATGACTTTTCCTGTGAACTCTACAGAATGTCTACATATTCAACTTTCCCCGCCGGGGTG
  CCTGTCTCAGAAAGGAGTCTTGCTCGTGCTGGTTTTTATTATACTGGTGTGAATGACAAG
  GTCAAATGCTTCTGTTGTGGCCTGATGCTGGATAACTGGAAACTAGGAGACAGTCCTATT
  CAAAAGCATAAACAGCTATATCCTAGCTGTAGCTTTATTCAGAATCTGGTTTCAGCTAGT
  CTGGGATCCACCTCTAAGAATACGTCTCCAATGAGAAACAGTTTTGCACATTCATTATCT
  CCCACCTTGGAACATAGTAGCTTGTTCAGTGGTTCTTACTCCAGCCTTTCTCCAAACCCT
  CTTAATTCTAGAGCAGTTGAAGACATCTCTTCATCGAGGACTAACCCCTACAGTTATGCA
  ATGAGTACTGAAGAAGCCAGATTTCTTACCTACCATATGTGGCCATTAACTTTTTTGTCA
  CCATCAGAATTGGCAAGAGCTGGTTTTTATTATATAGGACCTGGAGATAGGGTAGCCTGC
  TTTGCCTGTGGTGGGAAGCTCAGTAACTGGGAACCAAAGGATGATGCTATGTCAGAACAC
  CGGAGGCATTTTCCCAACTGTCCATTTTTGGAAAATTCTCTAGAAACTCTGAGGTTTAGC
  ATTTCAAATCTGAGCATGCAGACACATGCAGCTCGAATGAGAACATTTATGTACTGGCCA
  TCTAGTGTTCCAGTTCAGCCTGAGCAGCTTGCAAGTGCTGGTTTTTATTATGTGGGTCGC
  AATGATGATGTCAAATGCTTTTGTTGTGATGGTGGCTTGAGGTGTTGGGAATCTGGAGAT
  GATCCATGGGTAGAACATGCCAAGTGGTTTCCAAGGTGTGAGTTCTTGATACGAATGAAA
  GGCCAAGAGTTTGTTGATGAGATTCAAGGTAGATATCCTCATCTTCTTGAACAGCTGTTG
  TCAACTTCAGATACCACTGGAGAAGAAAATGCTGACCCACCAATTATTCATTTTGGACCT
  GGAGAAAGTTCTTCAGAAGATGCTGTCATGATGAATACACCTGTGGTTAAATCTGCCTTG
  GAAATGGGCTTTAATAGAGACCTGGTGAAACAAACAGTTCAAAGTAAAATCCTGACAACT
  GGAGAGAACTATAAAACAGTTAATGATATTGTGTCAGCACTTCTTAATGCTGAAGATGAA
  AAAAGAGAAGAGGAGAAGGAAAAACAAGCTGAAGAAATGGCATCAGATGATTTGTCATTA
  ATTCGGAAGAACAGAATGGCTCTCTTTCAACAATTGACATGTGTGCTTCCTATCCTGGAT
  AATCTTTTAAAGGCCAATGTAATTAATAAACAGGAACATGATATTATTAAACAAAAAACA
  CAGATACCTTTACAAGCGAGAGAACTGATTGATACCATTTTGGTTAAAGGAAATGCTGCG
  GCCAACATCTTCAAAAACTGTCTAAAAGAAATTGACTCTACATTGTATAAGAACTTATTT
  GTGGATAAGAATATGAAGTATATTCCAACAGAAGATGTTTCAGGTCTGTCACTGGAAGAA
  CAATTGAGGAGGTTGCAAGAAGAACGAACTTGTAAAGTGTGTATGGACAAAGAAGTTTCT
  GTTGTATTTATTCCTTGTGGTCATCTGGTAGTATGCCAGGAATGTGCCCCTTCTCTAAGA
  AAATGCCCTATTTGCAGGGGTATAATCAAGGGTACTGTTCGTACATTTCTCTCTTAA
  
  Clone variation with respect to NM_001166.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001166 unedited
  CTAGGCAGCCGCGCAGCTTCCGTGTTTGCTGCGCCCGCACTGCGATTTACAACCCTGAAG
  AATCTCCCTATCCCTATTTTGTCCCCCTGCAGTAATAAATCCCATTATGGAGATCTCGAA
  ACTTTATAAAGGGATATAGTTTGAATTCTATGGAGTGTAATTTTGTGTATGAATTATATT
  TTTAAAACATTGAAGAGTTTTCAGAAAGAAGGCTAGTAGAGTTGATTACTGATACTTTAT
  GCTAAGCAGTACTTTTTTGGTAGTACAATATTTTGTTAGGCGTTTCTGATAACACTAGAA
  AGGACAAGTTTTATCTTGTGATAAATTGATTAATGTTTACAACATGACTGATAATTATAG
  CTGAATAGTCCTTAAATGATGAACAGGTTATTTAATTNTTAAATGCAGTGTAAAAAGTGT
  GCTGTGGAAATTTTATGGCTAACTAAGTTTATGGAGAAAATACCTTCAGTTGATCAAGAA
  TAATAGTGGTATACAAAGTTAGGAAGAAAGTCACATGATGCTGCANGAAATGGGAACANA
  TACCAATGATATTTAACAAAGATAGAGTTTACAGTTTTTGAACTTTAAGCCAAATTCATT
  TGACATCAAGCACTATAGCAGGCACAGGTTCAACAAAGCTTGTGGGGTATTGACTTCCCC
  CCAAAAGTTGTTCACCTGAAGTAATTTAGCCCCCCTTTAGTAAATACCTATGAAGATATA
  GCTGGGGTGAACCTAAGCTTNTAAATAAGTGTGACCATATAGAAGGTTTTAATTACTTTT
  NGTTATTNGGAATAAATAGAGACTCTTGGGGTTGGCTTGTTAAAGGCCTTATAGGGAAAG
  AACCTGCATTTAATTTTCACCTTGGGCATAACAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001166 unedited
  ATTTTAATACCACATGTGAAAAGCACCAGAGACAATTCGGCACCATAACTCTGATGAACT
  CCAGAGTTCCTGGTTTCCAGTTCTTTTCTACACTATAATTTAGTATTCAAAGCTTTCTGA
  AAGAACAACAAATCCAGTAACTCCTGATTTGATGCATAACAAGCAGTGACACTACTCCCT
  TAGGTACGCATACATACTAATATAGTTCACCAAACATAAATCTTCCCTTGTAAATAAACA
  GATTAAGATTAAATATATGATACCATCTTTTCAGAAACAAGATTATTAGTACCAAAGCAG
  ACTAGAACATGAATGTTACTAATTGAAAAACTCATAATTCCCTTTTTACTTTAGATGGCT
  TCAAGTGTTCAACAATATTTTAAAGACCTTTTCATGCACGTTAAAATATAGACTATTTTT
  CTTTAAGAGAGAAATGTACGAACAGTACCAGTGATTATACGCCTGCAAATACGGCATTTT
  CTTAGAGAAGGGGCACATTCCCTGGCATACTACCCGATGACCACAGGGAATAAATACAAC
  AGAGACTTCTTTGTCCATGCCCGCTTTACAAGTTGGTTCTGGTTGCCGCCCGGTGAGAGG
  GGCTTCGGGGGACCGGACCGGAAGACACGTGCGGATCGCAAGATACCTTGATCACGGTTT
  GCGCGGGCCCAATTTCTGATGCATTCGGCGAGTGCATGTCGTTATCCACACGCATGCGGA
  GGACCTGCGCGGGCGCCGTCCGCGTGGCGGCCACTTGCGGGCTCTCCAGGGTCTGGGCGG
  ATGTAGCGCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001166
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001166.3, NP_001157.1
• RefSeq Size: 3753 bp
• RefSeq ORF: 1857 bp
• Locus ID: 329
• Cytogenetics: 11q22.2
• Domains: CARD, BIR, RING
• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
• Gene Summary: 'The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]'
  Transcript Variant: This variant (1) is the predominant transcript. Variants 1 and 2 encode the same isoform (1).