Gephyrin (GPHN) (NM_020806) Human Untagged Clone

CAT#: SC126619

GPHN (untagged)-Human gephyrin (GPHN), transcript variant 1


  "NM_020806" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GPHN
Synonyms GEPH; GPH; GPHRYN; HKPX1; MOCODC
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_020806, the custom clone sequence may differ by one or more nucleotides


ATGGCGACCGAGGGAATGATCCTTACTAACCACGACCATCAAATCCGTGTCGGAGTCCTTACAGTGAGTG
ATAGTTGCTTCAGGAATCTTGCAGAAGACCGCAGTGGGATAAATCTCAAAGATCTCGTACAAGATCCTTC
TTTGTTGGGTGGGACTATATCAGCATACAAGATAGTACCAGATGAAATAGAAGAAATCAAGGAAACCCTG
ATAGATTGGTGTGATGAAAAGGAACTTAATTTGATATTAACAACTGGAGGAACAGGATTTGCACCACGAG
ATGTCACTCCAGAGGCCACAAAAGAAGTAATAGAACGGGAAGCACCAGGGATGGCCCTGGCAATGCTGAT
GGGATCACTTAATGTTACACCTCTGGGCATGCTCTCTAGGCCTGTATGTGGAATCAGAGGGAAAACGCTC
ATAATTAACCTGCCAGGTAGCAAGAAAGGATCTCAGGAATGCTTTCAATTCATACTGCCAGCTCTACCTC
ATGCCATTGACCTTTTACGTGATGCCATTGTAAAAGTAAAGGAGGTGCATGATGAACTTGAAGATTTGCC
TTCCCCACCTCCCCCTCTTTCCCCTCCTCCTACTACCAGCCCCCATAAACAGACAGAAGACAAAGGAGTT
CAATGTGAGGAAGAGGAAGAAGAGAAGAAAGACAGTGGTGTTGCTTCAACAGAAGATAGTTCCTCATCAC
ATATAACTGCAGCAGCCATTGCTGCCAAGAAGCATCCATTCTACACCAGTCCTGCTGTTGTCATGGCACA
CGGTGAACAGCCCATCCCTGGTCTCATCAATTATTCCCATCATTCAACAGATGAACGGATTCCAGACTCC
ATCATTTCTCGTGGTGTTCAGGTGCTCCCACGAGACACAGCCTCCCTCAGCACTACTCCTTCAGAATCGC
CTCGTGCTCAGGCTACATCTCGCCTCTCTACAGCTTCCTGCCCAACACCAAAAGTCCAGTCCAGGTGCAG
CAGCAAGGAGAACATTCTCAGAGCCAGTCACAGTGCTGTCGATATCACCAAGGTGGCTAGAAGACATCGC
ATGTCTCCTTTTCCTCTGACATCTATGGACAAAGCCTTTATCACAGTCCTGGAGATGACTCCGGTGCTTG
GGACAGAAATCATCAATTACCGAGATGGAATGGGGCGAGTCCTTGCTCAAGATGTATATGCAAAAGACAA
TTTACCCCCCTTCCCAGCATCAGTAAAAGATGGCTATGCTGTCCGAGCTGCTGATGGCCCAGGAGATCGT
TTCATCATTGGGGAATCCCAAGCTGGTGAACAGCCAACTCAGACAGTAATGCCAGGACAAGTCATGCGGG
TTACAACAGGTGCTCCAATACCCTGCGGTGCTGATGCAGTAGTACAAGTGGAAGATACCGAACTTATCAG
GGAATCAGATGATGGCACTGAAGAACTTGAAGTGCGAATTCTGGTGCAAGCTCGGCCAGGCCAAGATATC
AGACCCATCGGCCATGACATTAAAAGAGGGGAATGTGTTTTGGCCAAAGGAACCCACATGGGCCCCTCAG
AGATTGGTCTTCTGGCAACTGTAGGTGTCACAGAGGTTGAAGTTAATAAGTTTCCAGTGGTTGCAGTCAT
GTCAACAGGGAATGAGCTGCTAAATCCTGAAGATGACCTCTTACCAGGGAAGATTCGAGACAGCAATCGT
TCAACTCTTCTAGCAACAATTCAGGAACATGGTTACCCCACGATCAACTTGGGTATTGTAGGAGACAACC
CAGATGACTTACTCAATGCCTTGAATGAGGGTATCAGTCGTGCTGATGTCATCATCACATCAGGGGGTGT
ATCCATGGGGGAAAAGGACTATCTCAAGCAGGTGCTGGACATTGATCTTCATGCTCAGATCCATTTTGGC
AGGGTTTTTATGAAACCAGGCTTGCCAACAACATTTGCAACTTTGGATATTGATGGTGTAAGAAAAATAA
TCTTTGCACTACCTGGGAATCCTGTATCGGCTGTGGTCACCTGCAATCTCTTTGTTGTGCCTGCACTGAG
GAAAATGCAGGGCATCTTGGATCCTCGGCCAACCATCATCAAAGCAAGGTTATCATGTGATGTAAAACTT
GATCCTCGTCCAGAATACCATCGGTGTATACTAACTTGGCATCACCAAGAACCACTACCTTGGGCACAGA
GTACAGGTAATCAAATGAGCAGCCGTCTGATGAGCATGCGCAGTGCCAATGGATTGTTGATGCTACCTCC
AAAGACAGAACAGTACGTGGAGCTCCACAAAGGCGAGGTGGTGGATGTCATGGTCATTGGACGGCTATGA


>OriGene 5' read for NM_020806 unedited
CGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTTCTCCCGGCTCCTGTCAGTG
CGGTGACTGCGCTGGGAAACATGGCGACCGAGGGAATGATCCTTACTAACCACGACCATC
AAATCCGTGTCGGAGTCCTTACAGTGAGTGATAGTTGCTTCAGGAATCTTGCAGAAGACC
GCAGTGGGATAAATCTCAAAGATCTCGTACAAGATCCTTCTTTGTTGGGTGGGACTATAT
CAGCATACAAGATAGTACCAGATGAAATAGAAGAAATCAAGGAAACCCTGATAGATTGGT
GTGATGAAAAGGAACTTAATTTGATATTAACAACTGGAGGAACAGGATTTGCACCACGAG
ATGTCACTCCAGAGGCCACAAAAGAAGTAATAGAACGGGAAGCACCAGCGATGGCCCTGG
CAATGCTGATGGGATCACTTAATGTTACACCTCTGGGCATGCTCTCTAGGCCTGTATGTG
GAATCAGAGGGAAAACGCTCATAATTAACCTGCCAGGTACCAAGAAAGGATCTCAGGAAT
GCTTTCAATTCATACTGCCAGCTCTACCTCATGCCATCGACCTTTCAACGGATGCCCATT
GAAAAGTAAAAGATGTGCCTGAAGAACTTGAGATTTGCCTTCCCACCTCCCCTTTTTCCC
TTCTCCTACTACCAGCCCCTTAACCGACAAAGACCAAGCATTCATGTGACGACAAACGAA
AAAAAAAAAACACCGGTGGTGCTTAACAAAGAACTTTCCTCTCCCTATACTGCACACCCT
CTGCTGCCAAATACCAACTCCTTATTCTCGGGGGGGGAAGGGCTTCCCAAACACAACTCC
TCTACACTCTTCTTTAAAACGCCCGGGTCAGCTTACTTTGCCTTTTCAATTTCCTGCCAA
CACAAAAATTGTGTTTCCACCCCACTCCCCATACTGTG
>OriGene 3' read for NM_020806 unedited
CCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTAAATAATGATCAAGGAATTTTTTT
ATTCATTAAGTTTCAGTATCATTACAGAAAATGTTATGGTACAGAATTGTTTAACATTAT
TTTGTCTTTGCTCTTGATTTCCACATGAATGCTGGTAACACTAATATCTGTACAAGATCA
GTCTTTGATTTTATTTTTTTGTTCTGTACAATTTTAAATGTATTGGTTAAAAAGGCTGTC
AGCACTTAAGGAAGCATTTTTTCTTCAGTTTGTTTCTTCAAATAAAAGGTGTCCAGTTAC
TGCCCAAGAGTACTGTGCCGTGAGGCTATTGGGGCGAGAAACCTCCCTGGATGCTCTGCA
GGGGATGGTTCTTGAGGCAAGGCAGAGCCTCCACCCAGTCAGTCTTCTTTTGGCACTGTG
CACATAAACACGAGATACATGAGAAAGAACAAGCAAAAGCTCTCTGTAAAGCAGTTATGA
AGCATACTAAGAAGGGAAATCCAAGTGTTGCCTACGCTAGTATAAATAAGCAGACAGCCT
TGATTTAAGAGCATAAGTAGTTGTATTCTAAAGATGAGAAAAACACAAGTTCTGCAGGCA
CCTACCGCTGTCTACTAAAAGCTATCGCTATCAGACCTATCATTGAACACACAAAGCAAT
TTGCCAGAAAGGATAAATCTGCCTTGAATAATCAGAACAGATTTTCTGTTAAGATTATTT
TGAGCGTCTTTTTCTTTAAAAGATATTAAATCCCTTGGAATATAATTCAAGATGTTGACT
ATCAGATCACCTTTATCCATATGGGAAACTAGCCTGGCCGTGCTTTTACAGGATCCGTCA
TGGATGGGGACTGCTTAAACTCTTCCCGCGGGGACCCTCTACCGCAAATGCCTGCCTCCC
ACCCCCCCTTTGGGACTCCCCTCCTGTTTGCCTTGGAGGAACCAAATACCTGGGCCTGGC
TTCCCTAAGACGGTCCTT
Restriction Sites NotI-NotI     
ACCN NM_020806
ORF Size 2310 bp
Insert Size 3370
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_020806.4, NP_065857.1
RefSeq Size 4318
RefSeq ORF 2310
Locus ID 10243
Domains MoCF_biosynth, MoeA_N, MoeA_C
Protein Families Druggable Genome
Gene Summary This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1), also known as GephP1, represents the longer transcript and encodes the longer isoform (1).

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