WASF2 (NM_006990) Human Untagged Clone

CAT#: SC126670

WASF2 (untagged)-Human WAS protein family, member 2 (WASF2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WASF2
• Synonyms: dJ393P12.2; IMD2; SCAR2; WASF4; WAVE2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126670 sequence for NM_006990 edited (data generated by NextGen Sequencing)
  ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGC
  GTTAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTG
  GGCAGCCTGAGTAAATATGCAGAGGACATTTTTGGAGAGCTCTTTACTCAGGCAAATACC
  TTTGCCTCTCGGGTAAGCTCCCTTGCTGAGAGGGTCGACCGACTACAGGTTAAAGTCACT
  CAGCTGGATCCCAAGGAAGAAGAAGTGTCACTGCAAGGAATCAACACCCGAAAAGCCTTC
  AGAAGTTCCACCATTCAAGACCAGAAGCTTTTTGACAGAAACTCTCTCCCAGTGCCTGTC
  TTAGAAACATACAATACCTGTGATACTCCTCCCCCTCTCAACAATCTTACCCCTTACAGG
  GACGATGGAAAAGAGGCACTCAAATTCTACACAGACCCTTCATACTTCTTTGATCTTTGG
  AAGGAGAAGATGCTGCAGGACACCAAGGATATCATGAAAGAGAAGAGAAAGCATAGGAAA
  GAAAAGAAAGATAATCCAAATCGAGGGAATGTAAACCCACGTAAAATCAAGACACGTAAG
  GAAGAGTGGGAGAAAATGAAGATGGGGCAAGAATTTGTGGAGTCCAAAGAAAAGCTGGGG
  ACTTCTGGGTATCCACCCACTTTGGTGTACCAGAATGGCAGCATTGGCTGTGTTGAAAAC
  GTGGATGCAAGTAGCTATCCGCCACCACCACAGTCAGACTCTGCTTCTTCACCTTCTCCT
  TCCTTCTCCGAGGACAACTTGCCTCCTCCACCAGCAGAATTCAGTTACCCAGTGGACAAC
  CAAAGAGGATCTGGTTTGGCTGGACCCAAAAGATCCAGTGTGGTCAGCCCAAGCCATCCA
  CCACCAGCTCCTCCTCTAGGCTCTCCACCAGGCCCTAAACCCGGGTTTGCTCCACCACCT
  GCCCCTCCGCCACCTCCGCCTCCAATGATAGGCATCCCACCTCCACCACCGCCTGTAGGA
  TTTGGGTCTCCAGGGACGCCTCCACCACCCTCACCCCCATCTTTCCCACCTCACCCTGAT
  TTTGCTGCCCCTCCACCTCCTCCTCCACCACCAGCAGCTGACTACCCAACTCTGCCACCA
  CCTCCCTTGTCCCAGCCAACAGGAGGAGCACCTCCTCCTCCCCCTCCTCCTCCTCCTCCG
  GGGCCCCCTCCTCCCCCTTTCACTGGTGCAGATGGCCAGCCTGCTATACCACCACCGCTT
  TCTGATACCACCAAGCCCAAGTCCTCCTTGCCTGCCGTGAGCGATGCCCGTAGCGACCTG
  CTTTCAGCCATCCGTCAAGGTTTTCAGCTGCGCAGGGTTGAGGAGCAGCGGGAACAAGAG
  AAGCGGGATGTTGTGGGCAATGACGTGGCCACCATCTTGTCTCGTCGCATTGCTGTTGAG
  TACAGTGACTCAGAAGATGACTCCTCTGAATTTGATGAGGACGACTGGTCCGATTAA
  
  Clone variation with respect to NM_006990.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006990 unedited
  TTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCGAGGCGGTCCG
  CGGGAGCACACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCG
  ACTGCGGGAGGCCAGGTTGTTTTTCACCATTCAGAACATTGCCTGAAGCAGGTCCACCAT
  GCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGT
  TAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGG
  CAGCCTGAGTAAATATGCAGAGGACATTTTTGGAGAGCTCTTTACTCAGGCAAATACCTT
  TGCCTCTCGGGTAAGCTCCCTTGCTGAGAGGGTCGACCGACTACAGGTTAAAGTCACTCA
  GCTGGATCCCAAGGAAGAAGAAGTGTCACTGCAAGGAATCAACACCCGAAAAGCCTTCAG
  AAGTTCCACCATTCAAGACCAGAAGCTTTTTGACAGAAACTCTCTCCCAGTGCCTGTCTT
  AGAAACATACAATACCTGTGATACTCCTCCCCCTCTCAACAATCTTACCCCTTACAGGGA
  CGATGGAAAAGAGGCACTCAAATTCTACACAGACCCTTCATACTTCTTTGATCTTTGGAA
  GGAGAAGATGCTGCAGGACACCAAGGATATCATGAAAGAGAAGAGAAAGCATAGGAAAGA
  AAAGAAAGATAATCCAAATCGAGGGAATGGTAACCCACGTAAAATCAAGACACGNTAGGG
  AAGAGTGGGAGAAAATGAAGATGGGNGCAGAAATTGTGGAGTCCAAAAAAAGCTGGGGAC
  TTCTGGGTATCCACCACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006990 unedited
  GCTTTGGACCGCGGCCCGCAATCCTANATCGAGTTTTTTTTTTTTTTTTTTGGTGCATAT
  GCATAAGTGGAGCCCAGAGGGCCTCTCGGCTCACTGGGTCCCCGGCCCCCCGAGCTGAGG
  AGGCTTCGCAAGGCCGGCTGCTACAAAGTGCCGAGCTTGGCTGCATAGATTTTAATGAGA
  GCGTCAGGCAGAGCTGTGCTGTTGCTCTCCGGGACTTGCAGATCATTACCAAACCAACTG
  TAGGATGAGAACATAGCACATCGAAACCCTAGGAGGTCACTGAGCTAATGATCTAATCCT
  ACCTTCCGCAGGCAGTGCCCCTCCCCACCTCCTCCTGCCCCCAGCCCTTTCCACGATGGA
  CTCAGTCCATTCCAGAAGCCAGGCCAACACCGCCCCCTTCAAGGTCAGAGCAGAATGACA
  GTGAGTGGCTCTAGCTCTCCCTTTTCCGGGCAAGGAGGATGGGGGTAATTTAGTCAAAGC
  CATTAGGCCCAAACCCTGGCCTGGCCAGGCCCCAGGTCTCCTATCTGGGAGAACCACTGC
  CCTCTGCCTGCCTCTCCAACTACTGCTGGGCTGCGGCCCAGGCGCCTTCAACGACCATTT
  TAGGGTTCTGATGAAAGCACCTTCGGCTTCTAAGGTGCAGGCTGGGAAACAAGGTGGGGG
  CCCACATAGCCTGGTGTCTCAGCATGGAGCTTAGTGCCAAGTCCTGTGCCAGAGACACCT
  GATGTGTAAAGAGGGAAGAGGGCACACTNTGGAGTGGCCCAGCAAGACGGCATGCTGTCC
  CCTACAGCTCAGTCCCCACACCTGAGTCCCAGAAAGAAGCAGAGGAAAAGCGCCAGCCAG
  GCACAGAGCAGACCCATGACTATCACTCCTCCTCAGCCGNAGGCTTTATGAGGCTTNNGC
  ATACTACACCATTGCTTGCTGGTAGGAAAGATCTGTTCTCTTGTTCAGGCNTGAAGCGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006990
• ORF Size: 1497 bp
• Insert Size: 4700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_006990.2, NP_008921.1
• RefSeq Size: 4270
• RefSeq ORF: 1497
• Locus ID: 10163
• Domains: WH2
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton
• Gene Summary: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.