CD48 (BC030224) Human Untagged Clone

CAT#: SC126734

CD48 (untagged)-Homo sapiens, similar to B-lymphocyte activation marker BLAST-1 precursor (BCM1 surface antigen) (Leucocyte antigen MEM-102) (TCT.1) (Antigen CD48), clone MGC:34616 IMAGE:5223308, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD48
• Synonyms: BCM1; BLAST; BLAST1; CD48 antigen (B-cell membrane protein); CD48 molecule; hCD48; mCD48; MEM-102; OTTHUMP00000025680; OTTHUMP00000060268; SLAMF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126734 sequence for BC030224 edited (data generated by NextGen Sequencing)
  ATGTGCTCCAGAGGTTGGGATTCGTGTCTGGCTCTGGAATTGCTACTGCTGCCTCTGTCA
  CTCCTGGTGACCAGCATTCAAGGTCACTTGGTACATATGACCGTGGTCTCCGGCAGCAAC
  GTGACTCTGAACATCTCTGAGAGCCTGCCTGAGAACTACAAACAACTAACCTGGTTTTAT
  ACTTTCGACCAGAAGATTGTAGAATGGGATTCCAGAAAATCTAAGTACTTTGAATCCAAA
  TTTAAAGGCAGGGTCAGACTTGATCCTCAGAGTGGCGCACTGTACATCTCTAAGGTCCAG
  AAAGAGGACAACAGCACCTACATCATGAGGGTGTTGAAAAAGACTGGGAATGAGCAAGAA
  TGGAAGATCAAGCTGCAAGTGCTTGGTGAGTCAGGGGAGCCAAAGAGCAAATCCCCACTC
  CAGTGGCCCCAGATGGACCACTGTAGGGCTTCCTGGGAGGCATGGGGCACTCTCGGGGAG
  GAGGAGAGAAAAACCTCAGGACAGGTTTGA
  
  Clone variation with respect to BC030224.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC030224 unedited
  GTATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATCGGCACGAGGCCTCGTGCCG
  AATTCGGCACGAGGACTGTCTCCTGCGTTGCTGGGAAGTTCTGGAAGGAAGCATGTGCTC
  CAGAGGTTGGGATTCGTGTCTGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGT
  GACCAGCATTCAAGGTCACTTGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCT
  GAACATCTCTGAGAGCCTGCCTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGA
  CCAGAAGATTGTAGAATGGGATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGG
  CAGGGTCAGACTTGATCCTCAGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGA
  CAACAGCACCTACATCATGAGGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGAT
  CAAGCTGCAAGTGCTTGGTGAGTCAGGGGAGCCAAAGAGCAAATCCCCACTCCAGTGGCC
  CCAGATGGACCACTGTAGGGCTTCCTGGGAGGCATGGGGCACTCTCGGGGAGGAGGAGAG
  AAAAACCTCAGGACAGGTTTGATTCATTTTTCCTTGATCCAATTCTATTTGGGAGTGAGC
  CTAGGTCAACAGATATCCAAATTAACAATCTTAGGACATTTAACACCTCTTCTGAAGTTA
  GTGAGTCTAAGCTTTGAAGAGAGGAAAACTAGAGATTTTCCTATTTCCTTCATTNTGNCC
  TGTGATCAACCTAAATCAGCTCAGCTCATCTTGATTATATCTCCGAAATTATGCTTCATT
  GGACTTAAGAAAAAAGANATGTTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for BC030224 unedited
  TGGCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAATCTTGTAGAGCT
  TGTTAACCAGAACACCACTGTAAGAGACCTTGAATCTTTTTGTTCCCAGGACTTTCTGAA
  TTTTCAGCCCATATGACATGGAAGAAGAGTTAGAAGGGGAATCTGACTGCTTGGATCAGG
  GACTGTCTGGCTGGTGGAACTTGAATGTATACAACACTCTTCATTTGCATGTTTTGACAT
  TTTAAAAAATGTTTTCACTTTCCTTATCTACTTTGACTCTAATAACATCCTGAAAGGTAA
  GTAGAATTATTCTCATAATATGATGAAGAACCCAAGGCTCTCAAGGGAACACCACTCTTG
  GATTATTTAGCCCCGCTCTTCTACAAGAATTGCATACCCCAACCCCTGGAGCCCCTCCCC
  ATATCCATGTTTCTGCCCTATAATCTGATCCTTTCACCAAAAATGTTTAGATCAGGTACA
  CACACCTGAACTAAATTGGGACTATCAGTTTCTCTCTCTTTAAATTGCCCTGAGAATTGA
  AACTCAGAGGAGCAAAAGTCTAAGTTTTGAGAGATAACATGTGTAAAATGGCAGGAATCC
  AAATCCATAGGCACAGTCCACAGATTCCTGAAGCTAGGGGTTCTGGCCCGAACCTGGTTT
  TCAATCTTCTCCCCTTAAGCCCTTCCTAGCTCTTTTAAACTCTNTGAATTGCTTTANATA
  GCCCTAGTTTCTTAAACTAAATTCTCCTTTTTTGGGTAAGGTACATTGAATTAGTTTCTG
  TTATTTGCTATCAAAAGAATCTTACCTAATATGGGCACAGAGATGTGAAGATCTTTNTTC
  AGGCTGCCAGCTAGTGAGCACTGACCAGNTNTGACCCCAGTCTGTCTGGCTCCCAGTATA
  TGCCTGAGTCCTATTCCTATACCCTGGTAGACTGGAGCTTGANTGGAAGTTTTTTGTCCT
  GCCATNATGAAAGTGAAAAATCTCTGATACTCTGCC
  
• Restriction Sites: NotI-NotI
• ACCN: BC030224
• Insert Size: 1750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC030224.1, AAH30224.1
• RefSeq Size: 1806 bp
• RefSeq ORF: 1806 bp
• Locus ID: 962
• Cytogenetics: 1q23.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Gene Summary: 'This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]'