SEP15 (NM_004261) Human Untagged Clone

CAT#: SC126778

41532 (untagged)-Human 15 kDa selenoprotein (SEP15), transcript variant 1 (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)

Specifications

Product Data

• Type: Human Untagged Clone
• Symbol: SELENOF
• Synonyms: SEP15
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126778 sequence for NM_004261 edited (data generated by NextGen Sequencing)
  ATGGTAGCGATGGCGGCTGGGCCGAGTGGGTGTCTGGTGCCGGCGTTTGGGCTACGGTTG
  TTGTTGGCGACTGTGCTTCAAGCGGTGTCTGCTTTTGGGGCAGAGTTTTCATCGGAGGCA
  TGCAGAGAGTTAGGCTTTTCTAGCAACTTGCTTTGCAGCTCTTGTGATCTTCTCGGACAG
  TTCAACCTGCTTCAGCTGGATCCTGATTGCAGAGGATGCTGTCAGGAGGAAGCACAATTT
  GAAACCAAAAAGCTGTATGCAGGAGCTATTCTTGAAGTTTGTGGATGAAAATTGGGAAGG
  TTCCCTCAAGTCCAAGCTTTTGTTAGGAGTGATAAACCCAAACTGTTCAGAGGACTGCAA
  ATCAAGTATGTCCGTGGTTCAGACCCTGTATTAAAGCTTTTGGACGACAATGGGAACATT
  GCTGAAGAACTGAGCATTCTCAAATGGAACACAGACAGTGTAGAAGAATTCCTGAGTGAA
  AAGTTGGAACGCATATAA
  
  Clone variation with respect to NM_004261.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004261 unedited
  TCTATTACCGCCCGTTGNCNCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGGAAAGTGCCTGGTTTGGGTAATCGAAAGCACCCAGTGATTGTAT
  TTGATGACTTTTAAGCTTTCATATGCCGTTATTTAATACCTGTCACTTCCAAATGAGAGA
  TGTAAGGGCAACGGCCGTTAGCGTTCTGTTTTGGATCAGGCTCTGGAGTGGACGCCCCTA
  GCTTAGGGGTCCTTCTAGGCAGCCAGAAACCTGCGGAAAATGGTAGCGATGGCGGCTGGG
  CCGAGTGGGTGTCTGGTGCCGGCGTTTGGGCTACGGTTGTTGTTGGCGACTGTGCTTCAA
  GCGGTGTCTGCTTTTGGGGCAGAGTTTTCATCGGAGGCATGCAGAGAGTTAGGCTTTTCT
  AGCAACTTGCTTTGCAGCTCTTGTGATCTTCTCGGACAGTTCAACCTGCTTCAGCTGGAT
  CCTGATTGCAGAGGATGCTGTCAGGAGGAAGCACAATTTGAAACCAAAAAGCTGTATGCA
  GGAGCTATTCTTGAAGTTTGTGGATGAAAATTGGGAAGGTTCCCTCAAGTCCAAGCTTTT
  GTTAGGAGTGATAAACCCAAACCTGTCAGAGGACTGCAAATCAAGTATGTCCGTGGTTCA
  GACCCTGATTAAAGCTTTTTGGACGACAATGGGAACATTGCTGAAGAACTGAACATCCTC
  AATGGAACCCAGACAGTGTAAAAAATTCCTGATGAAAATGTGAACCCTTTAAAACTTGCT
  TAAATTTGGGCTATCCTTTGTTCCTTTCCAATGAAATTCCGGCACCTAAAAAAATTTAGT
  TTGCTGCTTCATTGATAGCTTTACTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004261
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins.
• OTI Annotation: This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.

Reference Data

• RefSeq: NM_004261.3, NP_004252.2
• RefSeq Size: 1851
• Locus ID: 9403
• Gene Summary: The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2016]
  Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1).