Nck beta (NCK2) (NM_003581) Human Untagged Clone

CAT#: SC126794

NCK2 (untagged)-Human NCK adaptor protein 2 (NCK2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCK2
• Synonyms: GRB4; NCKbeta
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003581, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACAGAAGAAGTTATTGTGATAGCCAAGTGGGACTACACCGCCCAGCAGGACCAGGAGCTGGACATCA
  AGAAGAACGAGCGGCTGTGGTTGCTGGACGACTCCAAGACGTGGTGGCGGGTGAGGAACGCGGCCAACAG
  GACGGGCTATGTACCGTCCAACTACGTGGAGCGGAAGAACAGCCTGAAGAAGGGCTCCCTCGTGAAGAAC
  CTGAAGGACACACTAGGCCTCGGCAAGACGCGCAGGAAGACCAGCGCGCGGGATGCGTCCCCCACGCCCA
  GCACGGACGCCGAGTACCCCGCCAATGGCAGCGGCGCCGACCGCATCTACGACCTCAACATCCCGGCCTT
  CGTCAAGTTCGCCTATGTGGCCGAGCGGGAGGATGAGTTGTCCCTGGTGAAGGGGTCGCGCGTCACCGTC
  ATGGAGAAGTGCAGCGACGGTTGGTGGCGGGGCAGCTACAACGGGCAGATCGGCTGGTTCCCCTCCAACT
  ACGTCTTGGAGGAGGTGGACGAGGCGGCTGCGGAGTCCCCAAGCTTCCTGAGCCTGCGCAAGGGCGCCTC
  GCTGAGCAATGGCCAGGGCTCCCGCGTGCTGCATGTGGTCCAGACGCTGTACCCCTTCAGCTCAGTCACC
  GAGGAGGAGCTCAACTTCGAGAAGGGGGAGACCATGGAGGTGATTGAGAAGCCGGAGAACGACCCCGAGT
  GGTGGAAATGCAAAAATGCCCGGGGCCAGGTGGGCCTCGTCCCCAAAAACTACGTGGTGGTCCTCAGTGA
  CGGGCCTGCCCTGCACCCTGCGCACGCCCCACAGATAAGCTACACCGGGCCCTCGTCCAGCGGGCGCTTC
  GCGGGCAGAGAGTGGTACTACGGGAACGTGACGCGGCACCAGGCCGAGTGCGCCCTCAACGAGCGGGGCG
  TGGAGGGCGACTTCCTCATTAGGGACAGCGAGTCCTCGCCCAGCGACTTCTCCGTGTCCCTTAAAGCGTC
  AGGGAAGAACAAACACTTCAAGGTGCAGCTCGTGGACAATGTCTACTGCATTGGGCAGCGGCGCTTCCAC
  ACCATGGACGAGCTGGTGGAACACTACAAAAAGGCGCCCATCTTCACCAGCGAGCACGGGGAGAAGCTCT
  ACCTCGTCAGGGCCCTGCAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003581 unedited
  TGTAACTTCAGAGGTGTAATTAGCTGAAAACATCATCGTTTTGAAGAGTTCTGCGTTTTG
  CCAGTCACCTCTCAACTGTGTGCCAAAGAAGGACTCCATGAAAGATGACAGAAGAAGTTA
  TTGTGATAGCCAAGTGGGACTACACCGCCCAGCAGGACCAGGAGCTGGACATCAAGAAGA
  ACGAGCGGCTGTGGTTGCTGGACGACTCCAAGACGTGGTGGCGGGTGAGGAACGCGGCCA
  ACAGGACGGGCTATGTACCGTCCAACTACGTGGAGCGGAAGAACAGCCTGAAGAAGGGCT
  CCCTCGTGAAGAACCTGAAGGACACACTAGGCCTCGGCAAGACGCGCAGGAAGACCAGCG
  CGCGGGATGCGTCCCCCACGCCCAGCACGGACGCCGAGTACCCCGCCAATGGCAGCGGCG
  CCGACCGCATCTACGACCTCAACATCCCGGCCTTCGTCAAGTTCGCCTATGTGGCCGAGC
  GGGAGGATGAGTTGTCCCTGGTGAAGGGGTCGCGCGTCACCGTCATGGAGAAGTGCAGCG
  ACGGTTGGTGGCGGNGCAGCTACAACGGGCAGATCGGCTGGTTCCCCTCCAACTACGTCT
  TGGAGGAAGTGGACGAAGCGGCTGCGGAGTCCCCAGCTTCCTGAGCCTGCGCAAGGCGCC
  TCCCTGAGCATGGCCAGGGCTCCGCGTGCTGAATGTGTCCAAACGCTTACCCCTTCACTT
  TATCCCGGAGGAGACCTAACTTTCAAAAGGGGAAACATGGAGTGATTGAAAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003581 unedited
  NAAATTTGACTTGGACCCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTTTCC
  TTGGCATAATACTTTTTTTTATTACAATATCCAAAAAACTGGGTATGCAAGTTTAGGGGA
  TCTCAAGACCCCTTCTTCAATCGTAGGAATGTGCCATCTCAAGACGTTATATTTAAACTA
  TAAAGAAGTTCAAATGTAAAGGAAAAAGAAAATGCAATTTCTTCATAAACATTCTGTGTG
  TCTCTTACTACCAATCACATACTCTTTTGTAAACCCTGAAAAATTTCCCTGTAAATAATA
  TATATATATATAGTGTGTGTGTGTGTGTGTGTGTGTGCACGTGTGTGTGTGTATAAAGTG
  TTGGTAGCTCCCTTCCCCAAAGATCAGCTGTTTCCCTTAATCATCTGTATTAGTGTCAAC
  AAACGGCTACAGATACATATTTCTTTGAGAATTAAATACATAATTGTGAGATTCACACAA
  GCCGAAGGGCAAGAGGAAAAAGCACTATGTGGATGGCACATTTGGGGTAAATTACCAAAA
  CATCTGTCTTTCTGAGTCACCGGTTCTCTCTTTTGCAGACTGCCTTTCCAGGAAATTCTT
  TCTTTATTGCAAGCACAGCCCCAAAGGCACTGGGCAGCCCCCTCACTGCCATCGCACCCG
  GTGGCTCCAGCATTGCTATCACCAAACCTTTCGGCTCCCTGCCACACCCGGGTACCCCTG
  AAGCGCCACAGGACATGNGCCGAGGCCTGCTAGGACTGGGGCCCCCGCCCCTGTTTTCCC
  CACCCCTCTCGACGCCCCACAAACCGACGCCTGCCCTGGCGGCCCCCCAGGCCTCCCCCT
  CGCCCTCCCGTCTCCCTCCTTCCTTCCCAGGGCGCCCTCCTCTCCTCTCACTATCCCCGC
  CCCCCCACCCCCCTCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003581
• ORF Size: 1143 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003581.2, NP_003572.2
• RefSeq Size: 2698
• RefSeq ORF: 1143
• Locus ID: 8440
• Domains: SH2, SH3
• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance, ErbB signaling pathway, Pathogenic Escherichia coli infection, T cell receptor signaling pathway
• Gene Summary: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (A). Variants 1 and 2 both encode isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.