CERK (NM_182661) Human Untagged Clone

CAT#: SC126978

CERK (untagged)-Human ceramide kinase (CERK), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CERK
• Synonyms: ceramide kinase; dA59H18.2; dA59H18.3; DKFZp434E0211; FLJ21430; FLJ23239; hCERK; KIAA1646; lipid kinase LK4; LK4; LK4, hCERK, FLJ21430, FLJ23239, KIAA1646, MGC131878, dA59H18.2, dA59H18.3, DKFZp434E0211; MGC131878; OTTHUMP00000028554
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_182661, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAACGTGGCCCTGCTTCAGGTGATCCGCGGGAGGGGCCTCCACGCCAGCGCCGGGAAGGCTGCTGGG
  GCCTCCACACCTGCCTCATCACGGCGGCGAGGCTACGACAATCCGGCTGGGAGCATGACCTTGGCGTCTG
  TTCTGGGAGCACGGATGATAAGCTCTGGAAGCTGGCAGTGTGTAAAGCACTGGCAAGTTTGTTACTGTTA
  AAATGTCAAATACCAATGCTTTATATCGACGCGAAGTGCTTAACACAGCCGGGCTTGGGGGCAGTCAGGA
  GGAAGCTGGCCATCCGTGGAGGAGGGGCCGGTCCTGGACTCCCGCAGGACTCCTCTGAGGCAGGGCCTGA
  AGTCTGTACACGTGGTCCAGATTTGTCCTTGTCTTTTCTTCACACTGAGTTCTCTATATTTATTGAACAT
  CTTGTCCTTTTAAGCCAGAGTAGTGTAAACTGCGTCTCGGATGTCTGTCTTTTGCCTCGAAGCCACGATG
  GATCGCTGGTTTCCTCTGCAGCGCGAGGGCTCCGGCGACCAGAGGATTCTTCCCGGAAGGCATTCCTGCC
  GCGCTCCCCGGGGCACCCCTCAATTGTGTACTACGTCCTTGTTTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182661 unedited
  ATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCCTGGAACTGCGACGGGGAGG
  TCCTGCACAGCCCTGCCATCGAGGTCAGAGTCCACTGCCAGCTGGTTCGACTCTTTGCAC
  GAGGAATTGAAGAGAATCCGAAGCCAGACTCACACAGCTGAGAAGCCGGCGTCCTGCTCA
  CAAACTGGGAAAGTGTGAAAACTATTTAAGATAATTATTACAGACCAATTATGTTGATAT
  ATACATTTAAATGTAGAAATTTATTTTTGATAGTTAAATCTTGATTTTAGAAGAAAACCC
  TTTTGTCAACAATTTTGTGTACATATTTGGCATTTTCAGTTCTGTACGCATCTGCGGGTT
  GCAGCCCACGCCGCTTACTCTCAGCGGATGCAGCTGCTCACTTGGGGGCACTGGCCTCTT
  AGGTTTTAACGATGTCAACAGTGTAGTTTAGAAAATGGCCCGTTAGTGGCTCTATTGCAA
  TAATGTTAGGGACATTATATGATTTCCACGCAGGTCACACCATCTGGGCCTGAGGTAGCA
  GTGGGTCACTTTGATCCACTTTGCAGGACTTATTCTGTAACGGTTTGTGGCCAAGTTTTG
  GGAAGTGGTTGATTCTCTTTGCCTTCATTTCACCTTCCTCTTCGTTTACGGTTAGGACAT
  NCGCTGCTTGATCCTTACAATACTGTGCAACTGCAATGCACGTGGCCCTGCTTCAGGTGA
  ATCGCGGGAGGGGGCCTCCGCCACGCCGGNAGGCTGCTGGGGCCTNCACACTGCCTATCA
  CGGGGCGAGGCTCGACATNCGCTGGAGATACCTGGGGGTCTGTTCTGAGCACGAGATACT
  CTGAACTGGGCATGGTAAGCTGGCAAGTTTGTCTGTTTAATGTAATACATGCTAATNNAC
  CCAGGTAAACACGGCTTTGGGCATAGAAGATGCTTCCTTGGGGGGGGGGGGGGCCTGTCT
  CCAACCCTTAGGGGGGGAGTTTCACGGGGCAAATTTTGTTCTCTAACGTTTTTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_182661 unedited
  GATTACTTTTTTTCGTGGTCTTTCTCAAACATTTNCANANCAAATAATGCCATTTTCTAA
  TCTTGAAACCAGCAAGATTAGAAAGAGAATGAGGCCATCCTTTCACTCAGACTTTCCCAG
  TTACTCAAGATTGTATTCAGGAACGAAGTCAAACTCGGCCTCACTTCTTAATTAGAATAA
  ACTAGAATCAGGTCCATTGCATAACTGCTAATTGTTTTGCACCAGGGAGCCACAAAGGAA
  GCTAAAACTAGCCTTTCTAAGTTATCCTAAGTTTTTACTATCTAACCAGCACTTCTGATT
  TTTTTTCCCTTAAAACTCTAAAGTACAGGTGTTGTATGTCTGCCGCATCTGAAAGGCTGC
  CCCGGAAATCAGAGCCTATCTAGCGGGAATGTCTGGGCAGTCACCCCCATCCTGCGCGCA
  GATAGCAAAGGGCTGCTGGCAGGTGTCAGACACACGGTACCGCAACAGCAGTCCCGAGGT
  CTGAGATTCTGAATGTCAGCAGGTGGCTGGAGAGTATCACCAGAGCCACTCAGGAACCAG
  CCATGCGGAATGGCTGGGTTTCTTATTGAACATGAAATGCTTCCTCTTTGGCCTGGACTG
  TTTTGCTAAAATTGTTAGTGGGTTTTGGGGCAGGCCAGTGTATGGGAAACTTTTTTTTTT
  GTTGGGGGGGGGGCGATGGAGTCTCCCTCTGTTGCCCAGGCCTGGAGTGCAGTGGCGCAA
  TCTTGGCTCACCGCAACCTCCACCTCTTTCTTGGNGTCAAGCGATTCTCCTGCCTCAGCA
  TNCCTAGTAGCTGAGAATACAGGGCGTGCGCCCAACAGACTGGGCTAAGNTNGTGTATTT
  TTAGTAGAGGACGAGGTTTCACCATGTTTGGGCAAGCTGATCTCAACTCCTGACCTTTAG
  TGATCCACCGCCTCGGCTTCCAAGTGCTGGGATNCAGGCGTGAGCACCGGCCCAGCGGGA
  ACATTACAGGGACATAGCCTANAGAAACTTTGGGAACTTTGGAGGACCAATCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182661
• ORF Size: 606 bp
• Insert Size: 2850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_182661.1, NP_872602.1
• RefSeq Size: 3040
• RefSeq ORF: 606
• Locus ID: 64781
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• Gene Summary: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]). [supplied by OMIM, Mar 2008]