COX8A (NM_004074) Human Untagged Clone

CAT#: SC126992

COX8A (untagged)-Human cytochrome c oxidase subunit VIIIA (ubiquitous) (COX8A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COX8A
• Synonyms: COX; COX8; COX8-2; COX8L; VIII; VIII-L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126992 sequence for NM_004074 edited (data generated by NextGen Sequencing)
  ATGTCCGTCCTGACGCCGCTGCTGCTGCGGGGCTTGACAGGCTCGGCCCGGCGGCTCCCA
  GTGCCGCGCGCCAAGATCCATTCGTTGCCGCCGGAGGGGAAGCTTGGGATCATGGAATTG
  GCCGTTGGGCTTACCTCCTGCTTCGTGACCTTCCTCCTGCCAGCGGGCTGGATCCTGTCA
  CACCTGGAGACCTACAGGAGGCCAGAGTGA
  
  Clone variation with respect to NM_004074.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004074 unedited
  TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTTGGGCTACGGC
  TGACCGTTTTTTGTGGTGTACTCCGTGCCATCATGTCCGTCCTGACGCCGCTGCTGCTGC
  GGGGCTTGACAGGCTCGGCCCGGCGGCTCCCAGTGCCGCGCGCCAAGATCCATTCGTTGC
  CGCCGGAGGGGAAGCTTGGGATCATGGAATTGGCCGTTGGGCTTACCTCCTGCTTCGTGA
  CCTTCCTCCTGCCAGCGGGCTGGATCCTGTCACACCTGGAGACCTACAGGAGGCCAGAGT
  GAAGGGGTCCGTTCTGTCCCTCACACTGTGACCTGACCAGCCCCACCGGCCCATCCTGGT
  CATGTTACTGCATTTGTGGCCGGCCTCCCCTGGATCATGTCATTCAATTCCAGTCACCTC
  TTCTGCAATCATGACCTCTTGATGTCTCCATGGTGACCTCCTTGGGGGTCACTGACCCTG
  CTTGGTGGGGTCCCCCTTGTAACAATAAAATCTATTTAAACTTTAAAAAAAAAAAAAAAA
  AAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGT
  GGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCCTGGAGTTGCCACTCCAGTGC
  CCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGTCCTTCT
  ATAATATTATGGGGTGGAGGGGGGTTGGTATTGGACCCAGGGGCCAAAGTGGGAAAGACA
  ACCTGTAGGGCCTGCGGTGTTCTATTGGGAACCAAGCTGAAGGGCAGGGGCACAATCTTG
  GTTACTGGAATCCCGCCTTCTGGTTAAAGCGATCTCCTGCCTCACCTCCCCAGTGTCGGG
  T
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004074 unedited
  GTAACGCGGCCCGCTCTCTAGTATCGAGTTTTTTTCTTTTTTTTTTTTTTAAAGTTTAAA
  TAGATTTTATTGTTACAAGGGGGACCCCACCAAGCAGGGTCAGTGACCCCCAAGGAGGTC
  ACCATGGAGACATCAAGAGGTCATGATTGCAGAAGAGGTGACTGGAATTGAATGACATGA
  TCCAGGGGAGGCCGGCCACAAATGCAGTAACATGACCAGGATGGGCCGGTGGGGCTGGTC
  AGGTCACAGTGTGAGGGACAGAACGGACCCCTTCACTCTGGCCTTCTGTAGGTCTCCAGG
  TGTGACAGGATCCAGCCCGCTGGCAGGAGGAAGGTCACGAAGCAGGAGGTAAGCCCAACG
  GCCAATTTCATGATCCCAAGCTTACCCTCCGGCGGTAACGAATGGATCTTGGCGCGCGGT
  ACTGGGAGCCGTCGGTCCGAGCCTGTTAAGCCCCGTATCATTAGCGGCGTTAGGACGGAC
  ATGATGGCACGGAGTACACCACAAAAAACGGTTAGTCCGTACCCCAAGGCCTCGTGCCGA
  ATTCGCGGCCGTCCTATAGTGAGCCCTATTACAAAATTCTGACGGTTCACTAAACGAGCT
  CTGCTTATATAGACCTACAACCGTACACGCCTACCGCACATTTTGCGATAACGGGGCCGA
  GGTTATTACCACATTTTGAAAAAGCCTCGTTGTTTTTGGTGCCAAAACAAACTTCCATTG
  ACGTCTATGGGGCGGGAAACTTGGAAATCTCCGTGAGTTAAACCGCTATACACGCCCATT
  GGTGTACTGGTCATATCCGCTTACTTTGGGAATAGCGAGGACTATTACCTATATGTCCTG
  CCAATTAGAAAGCCCGTAAGGCCTGTCCTGGTTTATGCCAGGGGGCCATTTACCGCCTTG
  ACATATAAGGGGCGACTCTGCTTATATTCACTTGAGTCTGCCAATGGACATTTCCCTATA
  TCTCACCTCTGCGCCTAGGAAGTCCCATGGGGTTCTTGGCACTCACTACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004074
• ORF Size: 210 bp
• Insert Size: 510
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_004074.2, NP_004065.1
• RefSeq Size: 521
• RefSeq ORF: 210
• Locus ID: 1351
• Domains: COX8
• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]