LEPROT (NM_017526) Human Untagged Clone

CAT#: SC127307

LEPROT (untagged)-Human leptin receptor overlapping transcript (LEPROT), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LEPROT
• Synonyms: LEPR; OB-RGRP; OBRGRP; VPS55
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127307 sequence for NM_017526 edited (data generated by NextGen Sequencing)
  ATGGCGGGCGTTAAAGCTCTCGTGGCATTATCCTTCAGTGGGGCTATTGGACTGACTTTT
  CTTATGCTGGGATGTGCCTTAGAGGATTATGGCGTTTACTGGCCCTTATTCGTCCTGATT
  TTCCACGCCATCTCCCCCATCCCCCATTTCATTGCCAAAAGAGTCACCTATGACTCAGAT
  GCAACCAGTAGTGCCTGTCGGGAACTGGCATATTTCTTCACTACTGGAATTGTTGTTTCT
  GCCTTTGGATTTCCTGTTATTCTTGCTCGTGTGGCTGTGATCAAATGGGGAGCCTGCGGC
  CTTGTGTTGGCAGGCAATGCAGTCATTTTCCTTACAATTCAAGGGTTTTTCCTTATATTT
  GGAAGAGGAGATGATTTTAGCTGGGAGCAGTGGTAG
  
  Clone variation with respect to NM_017526.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017526 unedited
  AATATCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAGGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGCTGCCCGGGCCGTGGCAGGAAGCCGGAAGCAGCCGCGGCCCCAG
  TTCGGGAGACATGGCGGGCGTTAAAGCTCTCGTGGCATTATCCTTCAGTGGGGCTATTGG
  ACTGACTTTTCTTATGCTGGGATGTGCCTTAGAGGATTATGGCGTTTACTGGCCCTTATT
  CGTCCTGAGTTTCCACGCCATCTCCCCCATCCCCCATTTCATTGCCAAAAGAGTCACCTA
  TGACTCAGATGCAACCAGTAGTGCCTGTCGGGAACTGGCATATTTCTTCACTACTGGAAT
  TGTTGTTTCTGCCTTTGGATTTCCTGTTATTCTTGCTCGTGTGGCTGTGATCAAATGGGG
  AGCCTGCGGCCTTGTGTTGGCAGGCAATGCAGTCATTTTCCTTACAATTCACGGGTTTTT
  CCTTATATTTGGAAGAGGAGATGATTTTAGCTGGGAGCAGTGGTAGCACTTTATTCTGAG
  TACAGTGCATTGAATTTCTTAGAACTCATACTATCTGTATACATGTGCACATGCGGCATT
  TTACTATGAAATTTAATATGCTGGGTTTTTTAATACCTTTATATATCATGTTCACTTTCA
  GAGAGACTTCATAAGTAGGAGATGAGTTNTATTCTCAGCAGATAGACCTGTCACATTTAG
  ATTATGTTACTCACAGTATGTTACTTGTTTGGCTGNTCATGTAGTCACGGTGCTCTCAGA
  GCAATATCACGCAGTCTTGTAGGCAGCTGCCACATATGCAGTGCATCGAAACTTTTGCTT
  GGGGATGTGCTTGNAGAGGCGATACGCTGAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017526
• ORF Size: 396 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017526.2, NP_059996.1
• RefSeq Size: 1147
• RefSeq ORF: 396
• Locus ID: 54741
• Domains: Vps55
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]). [supplied by OMIM, Jul 2010]
  Transcript Variant: This variant (1) is dominant and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.