CHMP1B (NM_020412) Human Untagged Clone

CAT#: SC127309

CHMP1B (untagged)-Human chromatin modifying protein 1B (CHMP1B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHMP1B
• Synonyms: C10orf2; C18-ORF2; C18orf2; CHMP1.5; hVps46-2; Vps46-2; Vps46B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020412, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTAACATGGAGAAACACCTGTTCAACCTGAAGTTCGCGGCCAAAGAACTGAGTAGGAGTGCCAAAA
  AATGCGATAAGGAGGAAAAGGCCGAAAAGGCCAAAATTAAAAAGGCCATTCAGAAGGGCAACATGGAAGT
  TGCGAGGATACACGCCGAAAATGCCATCCGCCAGAAGAACCAGGCGGTGAATTTCTTGAGAATGAGTGCG
  CGAGTCGATGCAGTGGCTGCCAGGGTCCAGACGGCGGTGACGATGGGCAAGGTGACCAAGTCGATGGCTG
  GTGTGGTTAAGTCGATGGATGCGACATTGAAGACCATGAATCTGGAGAAGATTTCTGCTTTGATGGACAA
  ATTCGAGCACCAGTTTGAGACTCTGGACGTCCAGACGCAGCAAATGGAAGACACGATGAGCAGCACGACG
  ACGCTCACCACTCCCCAGAACCAAGTGGATATGCTGCTCCAGGAAATGGCAGATGAGGCGGGCCTCGACC
  TCAACATGGAGCTGCCGCAGGGCCAGACCGGCTCCGTGGGCACGAGCGTGGCTTCGGCGGAGCAGGATGA
  ACTGTCTCAGAGACTGGCCCGCCTTCGGGATCAAGTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020412 unedited
  CGTATTTGTATACGACNACTATAGGCGGCACGCGAATTCGCACCATAAACAAAGGACGGC
  GGCCGGGAGCGGACTTACCTTACCTTCTCTGCCTTCGGCGCGCTTCTCATCCGGGCCGCC
  GACCCAAAGGAGCCGTCCGACTATGTCTAACATGGAGAAACACCTGTTCAACCTGAAGTT
  CGCGGCCAAAGAACTGAGTAGGAGTGCCAAAAAATGCGATAAGGAGGAAAAGGCCGAAAA
  GGCCAAAATTAAAAAGGCCATTCAGAAAGGCAACATGGAAGTTGCGAGGATACACGCCGA
  AAATGCCATCCGCCAGAAGAACCAGGCGGTGAATTTCTTGAGAATGAGTGCGCGAGTCGA
  TGCAGTGGCTGCCAGGGTCCAGACGGCGGTGACGATGGGCAAGGTGACCAAGTCGATGGC
  TGGTGTGGTTAAGTCGATGGATGCGACATTGAAGACCATGAATCTGGAGAAGATTTCTGC
  TTTGATGGACAAATTCGAGCACCAGTTTGAGACTCTGGACGTCCAGACGCAGCATATGGA
  AGACACGATGAGCAGCACGACGACGCTCACCACTCCCCATAACCAAGTGGATATGCTGCT
  CCAGGAAATGGCAGATGATGCGGGCCTCGACCTCAACATGGAGCTGCCGCATGGCCAGAC
  CGGCTCCGTGGGCACGATCGTGGCTTCNGCGGAGCAGGATGAACTGTCTCATAGACTGGC
  CCGNCTTCGGGATCAAGTGTGACGGCAGAACCCGCTCTGATGTTTCCTGGCCATAGCCAC
  CCTCTAGAATGCTCTCTGTGTGCTAGAGAGATACTATACCCTAGAAACTCTGAACACGCC
  AGAATGCTGAAATGCCCTTCTACCTTTTGGNTTACAGCCCCCCTCACTAANTNANNGAAT
  CAGTATTCTGCACTCTTANCTGGATTCTAAGCTCTGATAGCTCGAATGGATGTATTTNAT
  AGCAGCCTTTAACAGACTAGTAATTNCGNGTTATGAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020412
• ORF Size: 600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020412.3, NP_065145.2
• RefSeq Size: 1290
• RefSeq ORF: 600
• Locus ID: 57132
• Domains: DUF279
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar 2008]