PHD finger protein 6 (PHF6) (NM_032458) Human Untagged Clone

CAT#: SC127378

PHF6 (untagged)-Human PHD finger protein 6 (PHF6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PHF6
• Synonyms: BFLS; BORJ; CENP-31
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127378 sequence for NM_032458 edited (data generated by NextGen Sequencing)
  ATGTCAAGCTCAGTTGAACAGAAAAAAGGGCCTACAAGACAGCGCAAATGTGGCTTTTGT
  AAGTCAAATAGAGACAAGGAATGTGGACAGTTACTAATATCTGAAAACCAGAAGGTGGCA
  GCGCACCATAAGTGCATGCTCTTTTCATCTGCTTTGGTATCATCACACTCTGATAATGAA
  AGTCTTGGTGGATTTTCTATTGAAGATGTCCAAAAGGAAATTAAAAGAGGCACGAAGCTG
  ATGTGTTCTTTGTGCCATTGTCCTGGAGCAACAATTGGTTGTGATGTGAAAACATGTCAC
  AGGACATACCACTACCACTGTGCATTGCATGATAAAGCTCAAATACGAGAGAAACCTTCA
  CAAGGAATTTACATGGTCTATTGCCGAAAACACAAGAAAACTGCACATAACTCCGAAGCT
  GATTTAGAAGAAAGTTTTAATGAACATGAACTGGAGCCCTCATCACCTAAAAGTAAAAAG
  AAAAGTCGCAAAGGAAGGCCAAGAAAAACTAATTTTAAAGGGCTGTCAGAAGATACCAGG
  TCCACATCCTCCCATGGAACAGATGAAATGGAAAGTAGTTCCTATAGAGATAGGTCTCCA
  CACAGAAGCAGCCCTAGTGACACCAGGCCTAAATGTGGATTTTGCCATGTAGGGGAGGAA
  GAAAATGAAGCACGAGGAAAACTGCATATATTTAATGCCAAGAAGGCAGCTGCCCATTAT
  AAGTGCATGTTGTTTTCTTCTGGCACAGTCCAGCTCACAACAACATCAAGAGCAGAATTT
  GGAGACTTTGATATTAAAACTGTACTTCAGGAGATTAAACGAGGAAAAAGAATGAAATGT
  ACACTTTGCAGTCAGCCTGGTGCTACTATTGGATGTGAAATAAAAGCCTGTGTTAAGACT
  TACCATTACCACTGTGGAGTACAAGACAAAGCTAAATACATTGAAAATATGTCACGAGGA
  ATTTACAAACTATACTGTAAAAATCATAGTGGAAATGATGAGAGAGATGAAGAAGATGAG
  GAACGAGAGAGTAAAAGCCGAGGAAAAGTAGAAATTGATCAGCAACAACTAACTCAGCAG
  CAACTTAATGGAAACTAG
  
  Clone variation with respect to NM_032458.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032458 unedited
  GTATACGACTCACTATTAGGCGGCCGCGACATTCGCACGAAGAAACAACCTCCGGCGACA
  GAACCCCGCTCTCAGGCACTGCTGGAGAACCGAGACCGACTTCTTTCTCTTTACCCTCAT
  TGGCGCTTCTCTCCTGCAGTCCGCCTCTGGGCCCTGCCGCATTTCTTGAGACTTAAAGTG
  GCATTCTAAAGGCAATTTAAAAATCATGTCAAGCTCAGTTGAACAGAAAAAAGGGCCTAC
  AAGACAGCGCAAATGTGGCTTTTGTAAGTCAAATAGAGACAAGGAATGTGGACAGTTACT
  AATATCTGAAAACCAGAAGGTGGCAGCGCACCATAAGTGCATGCTCTTTTCATCTGCTTT
  GGTATCATCACACTCTGATAATGAAAGTCTTGGTGGATTTTCTATTGAAGATGTCCAAAA
  GGAAATTAAAAGAGGCACGAAGCTGATGTGTTCTTTGTGCCATTGTCCTGGAGCAACAAT
  TGGTTGTGATGTGAAAACATGTCACAGGACATACCACTACCACTGTGCATTGCATGATAA
  AGCTCAAATACGAGAGAAACCTTCACAGGAATTTACATGGTCTATTGCCGAAAACCAAGA
  AAACTGCACATAACTCCGAAGCTGATTAGAAGAAAGTTTTAATGAACATGAACTGGAGCC
  CTCATCACCTAAAAGAAAAAAAAAAGTCGCAAAGGAAGGCCAAGAANAACTAATTNTAAG
  AGGGCTGTCAGAAGATACCAGGTCCACATCCTCCCATGGAACAGATGAATGGGAAAGGTA
  GTTCCTATAGAGAATAGGTCTTCAACAGAAACAGCCCTAATGACACCCAGCCTAATGGGG
  GAATTTCGCATGTAGGGGAGGAAGAAATTGAGCCGAAGGAAACTGCTATTTTTTATGCCC
  AGAAGCAGCCGGCCTTATAAGGCCCGGGGGGTTTTTTTGGGGCCAANCCAGCTAAACACC
  TCAGAACGAATTGGGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032458 unedited
  TACTATGGACGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTGAAAGGCATAAGTCATTTATTGAATGAATAGTATATGCAAGAATACCAATAAA
  AGGAAACTAATACTACAAACTACAATTTTGAAAATAAAGCCAATATAACAGGAACAAAAT
  ATACATAACATGAGAGGAATGTTTGATTTTTGACCCATAATGCATTCCTTATCTTTACAA
  TTAACCTAAATGTCTGTTAAAACAAAACTGTATACCTTGGTCTAACTTCAGCGCTTTTTT
  TAAAAAAGCAACAACACTTTAAAACACTTTTTCTTTTGCTTTGAAATATTTGAAATTCAC
  ACATTTGTTCAAGTACACAGATTCTGATTCAATAGCAAATCTACAGATCTTGGTATCTCT
  TAATATCTTGAGTAGCATGTACTTCTGAGCAAGTACTATCTGAAATTCTAAAACTGCTGA
  TTCTTGAAATAAAATTTACTTCAGTTGGGGGTTTTTAATAACTTGAGATGAAAGTAAAAT
  TCACCCCCTGCCCCCCTCCCCCAGGAACAAAGAGCTCTTCTTAAAAGTATAGAAACTCAA
  GTCTATCTTTCTACTCTAAAGAACATTTCCTACTAACATTTCTGGTAAGGCAATAAATGC
  TCCAGAATAATCTTCAATATACGCTTGCAAAGATTACACTGTTTAATATCNNTTACCAAA
  ACCNACCCNAAAAGGAAAAAGAAGAANAAGACGCTTAAAAATTCAGCTAAATATGCATAA
  AGACAGTAACGGCAGTATTTTTGAATGATGTAAAGTTAAATACTATCAATAAGGCATGCT
  ATTAAAACTACGTTAGACTTAAAAAGTACGAAATCCTGCTTAGGCCATTTCTAATTAAAC
  ACATGGATTCTACAAAAGATAAGCTCCTGAACTAAACTGCATTTTAATGTAGGCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032458
• ORF Size: 1098 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_032458.2, NP_115834.1
• RefSeq Size: 4772
• RefSeq ORF: 1098
• Locus ID: 84295
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (2, also called the 'PHF6b' variant) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).