MX2 (NM_002463) Human Untagged Clone

CAT#: SC127459

MX2 (untagged)-Human myxovirus (influenza virus) resistance 2 (mouse) (MX2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MX2
• Synonyms: MXB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127459 sequence for NM_002463 edited (data generated by NextGen Sequencing)
  ATGTCTAAGGCCCACAAGCCTTGGCCCTACCGGAGGAGAAGTCAATTTTCTTCTCGAAAA
  TACCTGAAAAAAGAAATGAATTCCTTCCAGCAACAGCCACCGCCATTCGGCACAGTGCCA
  CCACAAATGATGTTTCCTCCAAACTGGCAGGGGGCAGAGAAGGACGCTGCTTTCCTCGCC
  AAGGACTTCAACTTTCTCACTTTGAACAATCAGCCACCACCAGGAAACAGGAGCCAACCA
  AGGGCAATGGGGCCCGAGAACAACCTGTACAGCCAGTACGAGCAGAAGGTGCGCCCCTGC
  ATTGACCTCATCGACTCCCTGCGGGCTCTGGGTGTGGAGCAGGACCTGGCCCTGCCAGCC
  ATCGCCGTCATCGGGGACCAGAGCTCGGGCAAGAGCTCTGTGCTGGAGGCACTGTCAGGA
  GTCGCGCTTCCCAGAGGCAGCGGAATCGTAACCAGGTGTCCGCTGGTGCTGAAACTGAAA
  AAGCAGCCCTGTGAGGCATGGGCCGGAAGGATCAGCTACCGGAACACCGAGCTAGAGCTT
  CAGGACCCTGGCCAGGTGGAGAAAGAGATACACAAAGCCCAGAACGTCATGGCCGGGAAT
  GGCCGGGGCATCAGCCATGAGCTCATCAGCCTGGAGATCACCTCCCCTGAGGTTCCAGAC
  TTGACCATCATTGACCTTCCCGGCATCACCAGGGTGGCTGTGGACAACCAGCCCCGAGAC
  ATCGGACTGCAGATCAAGGCTCTCATCAAGAAGTACATCCAGAGGCAGCAGACGATCAAC
  TTGGTGGTGGTTCCCTGTAACGTGGACATTGCCACCACGGAGGCGCTGAGCATGGCCCAT
  GAGGTGGACCCGGAAGGGGACAGGACCATCGGTATCCTGACCAAACCAGATCTAATGGAC
  AGGGGCACTGAGAAAAGCGTCATGAATGTGGTGCGGAACCTCACGTACCCCCTCAAGAAG
  GGCTACATGATTGTGAAGTGCCGGGGCCAGCAGGAGATCACAAACAGGCTGAGCTTGGCA
  GAGGCAACCAAGAAAGAAATTACATTCTTTCAAACACATCCATATTTCAGAGTTCTCCTG
  GAGGAGGGGTCAGCCACGGTTCCCCGACTGGCAGAAAGACTTACCACTGAACTCATCATG
  CATATCCAAAAATCGCTCCCGTTGTTAGAAGGACAAATAAGGGAGAGCCACCAGAAGGCG
  ACCGAGGAGCTGCGGCGTTGCGGGGCTGACATCCCCAGCCAGGAGGCCGACAAGATGTTC
  TTTCTAATTGAGAAAATCAAGATGTTTAATCAGGACATCGAAAAGTTAGTAGAAGGAGAA
  GAAGTTGTAAGGGAGAATGAGACCCGTTTATACAACAAAATCAGAGAGGATTTTAAAAAC
  TGGGTAGGCATACTTGCAACTAATACCCAAAAAGTTAAAAATATTATCCACGAAGAAGTT
  GAAAAATATGAAAAGCAGTATCGAGGCAAGGAGCTTCTGGGATTTGTCAACTACAAGACA
  TTTGAGATCATCGTGCATCAGTACATCCAGCAGCTGGTGGAGCCCGCCCTTAGCATGCTC
  CAGAAAGCCATGGAAATTATCCAGCAAGCTTTCATTAACGTGGCCAAAAAACATTTTGGC
  GAATTTTTCAACCTTAACCAAACTGTTCAGAGCACGATTGAAGACATAAAAGTGAAACAC
  ACAGCAAAGGCAGAAAACATGATCCAACTTCAGTTCAGAATGGAGCAGATGGTTTTTTGT
  CAAGATCAGATTTACAGTGTTGTTCTGAAGAAAGTCCGAGAAGAGATTTTTAACCCTCTG
  GGGACGCCTTCACAGAATATGAAGTTGAACTCTCATTTTCCCAGTAATGAGTCTTCGGTT
  TCCTCCTTTACTGAAATAGGCATCCACCTGAATGCCTACTTCTTGGAAACCAGCAAACGT
  CTCGCCAACCAGATCCCATTTATAATTCAGTATTTTATGCTCCGAGAGAATGGTGACTCC
  TTGCAGAAAGCCATGATGCAGATACTACAGGAAAAAAATCGCTATTCCTGGCTGCTTCAA
  GAGCAGAGTGAGACCGCTACCAAGAGAAGAATCCTTAAGGAGAGAATTTACCGGCTCACT
  CAGGCGCGACACGCACTCTGTCAATTCTCCAGCAAAGAGATCCACTGA
  
  Clone variation with respect to NM_002463.1
  661 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002463 unedited
  TTTGTATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGGGAAGATCGGAGGTGC
  CAAGTAGCAGAGAAAGCATCCCCCAGCTCTGACAGGGAGACAGCACATGTCTAAGGCCCA
  CAAGCCTTGGCCCTACCGGAGGAGAAGTCAATTTTCTTCTCGAAAATACCTGAAAAAAGA
  AATGAATTCCTTCCAGCAACAGCCACCGCCATTCGGCACAGTGCCACCACAAATGATGTT
  TCCTCCAAACTGGCAGGGGGCAGAGAAGGACGCTGCTTTCCTCGCCAAGGACTTCAACTT
  TCTCACTTTGAACAATCAGCCACCACCAGGAAACAGGAGCCAACCAAGGGCAATGGGGCC
  CGAGAACAACCTGTACAGCCAGTACGAGCAGAAGGTGCGCCCCTGCATTGACCTCATCGA
  CTCCCTGCGGGCTCTGGGTGTGGAGCAGGACCTGGCCCTGCCAGCCATCGCCGTCATCGG
  GGACCAGAGCTCGGGCAAGAGCTCTGTGCTGGAGGCACTGTCAGGAGTCGCGCTTCCCAG
  AGGCAGCGGAATCGTAACCAGGTGTCCGCTGGTGCTGAAACTGANAAAGCAGCCCTGTGA
  GGCATGGGCCGGAAGGATCAGCTACCGGAACACCGAGCTAGAGCTTCAGGACCCTGGCCA
  GGTGGAGAAAGAGAACACAAAGCCCAAAACGTCATGGCCCGGGAATGGCCGGGGCATCAN
  CCATGAGCTCATCAGCCTGGGAGATCACCTNCCCCTGAGGGTCCCAGACTTGACCATCAT
  TTGACCTTCCCGGCATCACCAGGGTGGGCTGTTGGAACACCAGCCCCCGAGACTTCGGAC
  TGGCAGATCAAGGCTCTCATCAGGAAGTACATCCAGAGGCAGCAGACGATCAACTTGGGG
  GGGGGGGNNTCCTGTTACGTTGGACATGGCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002463 unedited
  TGTGGCTTTTCTAAGCTTTACATGCTGCAGTGCTGTGCAGGGAGATGGACATACAAAATA
  AGAATTTGACCCAGACCTTCCCCCTCTGGGGTCTCATAATCTTGTAGGGGGAAGGGAATA
  CAAATACAAATTAGCGAAGAATGATAGCAGTATCTTAGGACACTGTAACTGTGTGCTACG
  GGACCCAAGGACTGGAGAGCCATCCCTTCGTGAAGGTCAGGGAAGAGCTGGGTGGTGGAG
  AGAGCTGAGCCTGTGTGGACCCCTGATGCATGCTCTGATGCTGAGGGAGTACAGTAGAGA
  TGGACACTGATAGTGACAGAAGAGTTTGGCCCCAAAGCAGAAGCGGCATCCTGCACCGAC
  TCCCCTTAGAATGAATGAGTACGCACAAGAAAACAACCACAGGCATCGCCGCCCTTCAGT
  GGATCTCTTTGCTGGAGAATTGACAGAGTGCGTGTCGCGCCTGAGTGAGCCGGTAAATTC
  TCTTCTTAAGGATTCTTCTTTTGGTAGCGGTCTCACTCTGCTCTTGAAGCAGCCAGGAAT
  AGCGATTTTTTTCCTGGTAGATCTGCATCATGGCTTTCTGCAAGGAGTCACCATTCTCTC
  GGAGCATAAAATACTGAATTATAAATGGGATCTGGTTGGCGAGACGGTTGTTGGTTTCCA
  AGAAGTAGGCATTCACGTGGATGCCTATTTCATTAAAGGAGGAAACCGACCACTCTTACT
  TGGAATATGAGCAGTTAACTTATATTCTGTGAAGGCGTTCCCACAGGCTAAAGACTTTTT
  CTCCGACTTTCTTCCGAACAACCTTGTAAAGTGGATTTGACAAAAATCATCTGCTCATTC
  CGATCGTAACTGGTCCATGTTTTTGCCCTTGCGCGGAGTGAACGTTTAGGTATCCATCGG
  CCCTTCACAATTGGTACGCTTTATAATCCGCCTTAGTTCCCGCCCCCTATTAAACTTGTA
  CCAACCCTCGCCCCCGGAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002463
• ORF Size: 2148 bp
• Insert Size: 2800
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_002463.1, NP_002454.1
• RefSeq Size: 2961
• RefSeq ORF: 2148
• Locus ID: 4600
• Domains: dynamin_2, dynamin, GED
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]