LIN7C (NM_018362) Human Untagged Clone
CAT#: SC127489
LIN7C (untagged)-Human lin-7 homolog C (C. elegans) (LIN7C)
"NM_018362" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | LIN7C |
Synonyms | LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_018362, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCGCTAGGGGAACCCGTGCGGCTGGAGAGAGATATTTGTAGAGCAATTGAATTATTGGAAAAAC TACAAAGGAGTGGAGAAGTACCACCACAGAAACTTCAGGCTTTGCAAAGAGTCCTTCAAAGTGAATTCTG CAATGCTGTGAGAGAGGTATATGAACATGTCTATGAGACTGTGGACATCAGTAGCAGTCCTGAAGTGAGA GCGAACGCTACTGCAAAGGCTACTGTTGCTGCATTTGCTGCCAGTGAAGGACATTCTCATCCTCGAGTTG TTGAGCTACCAAAAACAGAAGAGGGCCTTGGATTCAATATTATGGGAGGCAAAGAACAAAACTCTCCAAT CTATATATCCCGAATAATTCCAGGTGGAATTGCTGATAGACATGGGGGCCTCAAACGTGGAGATCAACTC CTCTCTGTTAATGGAGTGAGTGTTGAAGGAGAACATCATGAAAAAGCTGTAGAACTGCTGAAAGCCGCAC AAGGAAAGGTTAAATTAGTGGTACGATACACACCCAAAGTCTTAGAAGAAATGGAGTCGCGCTTTGAAAA AATGAGATCAGCAAAACGCAGGCAACAGACCTAA >OriGene 5' read for NM_018362 unedited
CCGCGAATTCGGCACCAGGATGGCGGCGCTAGGGGAACCCGTGCGGCTGGAGAGAGATAT TTGTAGAGCAATTGAATTATTGGAAAAACTACAAAGGAGTGGAGAAGTACCACCACAGAA ACTTCAGGCTTTGCAAAGAGTCCTTCAAAGTGAATTCTGCAATGCTGTGAGAGAGGTATA TGAACATGTCTATGAGACTGTGGACATCAGTAGCAGTCCTGAAGTGAGAGCGAACGCTAC TGCAAAGGCTACTGTTGCTGCATTTGCTGCCAGTGAAGGACATTCTCATCCTCGAGTTGT TGAGCTACCAAAAACAGAAGAGGGCCTTGGATTCAATATTATGGGAGGCAAAGAACAAAA CTCTCCAATCTATATATCCCGAATAATTCCAGGTGGAATTGCTGATAGACATGGGGGCCT CAAACGTGGAGATCAACTCCTCTCTGTTAATGGAGTGAGTGTTGAAGGAGAACATCATGA AAAAGCTGTAGAACTGCTGAAAGCCGCACAAGGAAAGGTTAAATTAGTGGTACGATACAC ACCCAAAGTCTTAGAAGAAATGGAGTCGCGCTTTGAAAAATGAGATCAGCAAAACGCAGG CAACAGACCTAATACATTTCAAAACTTGATATTTCATTTTGCGTTTTAGCTAGAGAAGTT TTCCTTGTGACTTACTAATGGCTGCAATGCCAATGATTGNTAGAAAACAACAAATTTATC ATGAAATTT |
Restriction Sites | NotI-NotI |
ACCN | NM_018362 |
ORF Size | 594 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | A TrueClone. |
Reference Data | |
RefSeq | NM_018362.2, NP_060832.1 |
RefSeq Size | 4729 |
RefSeq ORF | 594 |
Locus ID | 55327 |
Domains | PDZ, L27 |
Protein Families | Druggable Genome |
Gene Summary | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. [UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208758 | LIN7C (Myc-DDK-tagged)-Human lin-7 homolog C (C. elegans) (LIN7C) |
USD 98.00 |
|
RG208758 | LIN7C (GFP-tagged) - Human lin-7 homolog C (C. elegans) (LIN7C) |
USD 460.00 |
|
RC208758L1 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), Myc-DDK-tagged |
USD 768.00 |
|
RC208758L2 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), mGFP tagged |
USD 620.00 |
|
RC208758L3 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), Myc-DDK-tagged |
USD 620.00 |
|
RC208758L4 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), mGFP tagged |
USD 620.00 |
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