KPNA4 (NM_002268) Human Untagged Clone

CAT#: SC127533

KPNA4 (untagged)-Human karyopherin alpha 4 (importin alpha 3) (KPNA4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KPNA4
• Synonyms: IPOA3; QIP1; SRP3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127533 sequence for NM_002268 edited (data generated by NextGen Sequencing)
  ATGGCGGACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGC
  GACTTGGAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAA
  AGAGATGAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCT
  GATATAGATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCT
  TCAAGTGATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCC
  AGTGATCGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTC
  CATTGTCTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACA
  AACATTGCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCA
  CTTTTCCTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCA
  TTGGGAAATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTT
  GTGAAACCTTTACTTTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAAATGTT
  ACTTGGGTTATGGTCAACTTATGTCGCCACAAAGACCCACCACCACCAATGGAAACCATT
  CAGGAGATTCTTCCAGCCCTTTGTGTTTTAATTCATCACACAGATGTAAATATACTGGTA
  GACACAGTCTGGGCCCTCTCTTACCTTACTGATGCTGGCAATGAACAAATACAGATGGTA
  ATAGACTCTGGAATAGTTCCTCATTTGGTTCCTCTGCTCAGCCACCAGGAAGTTAAAGTT
  CAGACTGCTGCACTTAGAGCTGTGGGCAACATTGTTACTGGAACTGATGAGCAAACACAA
  GTAGTTTTGAACTGTGATGCTCTTTCACACTTCCCAGCACTCCTGACACATCCCAAAGAG
  AAAATTAATAAAGAAGCAGTGTGGTTCCTCTCCAACATCACTGCAGGAAATCAGCAGCAG
  GTACAGGCAGTAATTGATGCCAATCTTGTACCAATGATAATACACCTTTTGGATAAGGGG
  GATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGG
  AAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTG
  ACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAA
  ATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAG
  AAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATC
  ATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCA
  ATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAG
  TTTTAG
  
  Clone variation with respect to NM_002268.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002268 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGCCCGGCCATGGCG
  GACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGCGACTTG
  GAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAAAGAGAT
  GAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCTGATATA
  GATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCTTCAAGT
  GATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCCAGTGAT
  CGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTCCATTGT
  CTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACAAACATT
  GCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCACTTTTC
  CTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCATTGGGA
  AATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTTGTGAAA
  CCTTTACTNTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAATGTTACTTGGG
  TTATGGGTCACTTATGTCGCCCAAAGACCCACCACCACCAATGGGAACCATTCANGAGAT
  TCTTNCACCTTNNTGTGTTTAATNCATCACACAGATGTAAATATACTGGTAGACACAGTC
  TGGGCCCTCTCTTNACTTACTGATGCTGGCATGAACAATACAGATGGTATAGACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002268 unedited
  NTTTGCTCTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTGCTTTAAGTTTTAATGGTTATTTCCCCAAAACAACCTAACCTGCA
  CTCTACTTGGATAAATTTTACAAGCTAGTTTTCTGCTGCTTCTAATTTTAAACTTTAACC
  ATGTTTCTGATGACAAGGAATGCTGCAAAAATACTCTAGTTCAACAAAGAGTTATGATCA
  CCAAATAATTTTTATCCCTTCTACAGGGGTTCAAAATTACCAGTTGATTTTTAAACACAA
  AGTAGATATAGATGCTAATGGGGGCTAATCTGGGATGTTTCTTATAACAAACTGGTGTTC
  ATGCAACACTTGTGCTCAAAGGGGAAGGCACAGGATTTCCTACAATGAGCCACCTTATAA
  AGAGTTCTTTTTGTACAAATTAATTTATGTCACATTTAATTTAATGGGCATAACCTCAAA
  ACTGAGGGATTATTCCAATTTATAAAAACCACTTGCATAACTTTTATGCAAGTTTTAAAA
  ATACAAAGTTTTCTCCCTAAAGTGGCTCAAAATAAATTGGTCATGGCTGCCTACATCTAA
  GATAAAAAGATTCTAAAACAATTGAACAGATTAGGCCTATTATTAAAGGTGTTCAAACCA
  TTACTTGATTTGGACATCTACTCAAACCTCTTCATCGGTCTTTATTCAGCAGTACATATG
  CACCAAATTCCCATTTTAGAAGTTTCCATATCATTTTCATAGAAAACAAAGTTTGGAAAC
  CAGTAACATTTAAACACAGCACGGGATTNCTACACCACTGGAACTTTTTTCTTTCTCTTC
  TTTACAGGACTCAACAAAATCTAAATGAACTATGCTGTAAATTTACCTCCTGCAAAGATC
  TTTTAGTTATCTCTTGAAATGAAAGGAAAGGCTTTTAAGCACATTTTACTGTTTTTACCT
  TTTATGGCAACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002268
• Insert Size: 4040 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002268.3, NP_002259.1
• RefSeq Size: 3816 bp
• RefSeq ORF: 1566 bp
• Locus ID: 3840
• Cytogenetics: 3q25.33
• Domains: Armadillo_seg, IBB
• Gene Summary: 'The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]'