Frizzled 2 (FZD2) (NM_001466) Human Untagged Clone

CAT#: SC127603

FZD2 (untagged)-Human frizzled family receptor 2 (FZD2)


  "NM_001466" in other vectors (6)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol FZD2
Synonyms fz-2; Fz2; fzE2; hFz2; OMOD2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001466 edited
GAATTCGGCACGAGGGGAGAGAGGGCAGCAGCGCGCGGTGTCTCCGGCTGCTCAGTCCGA
CCGCGGCAAGCAAGCGGGCAGGCGCACCGCCCCCTCCCCCGCCCGGCCTCCCCAACTCTG
CGGCCGCGAGTAAAGTTTGCAAAGAGGCGCGGGAGGCGGCAGCCGCAGCGAGGAGGCGGC
GGGGAAGAAGCGCAGTCTCCGGGTTGGGGGCGGGGGCGGGGGGGGCGCCAAGGAGCCGGG
TGGGGGGCGGCGGCCAGCATGCGGCCCCGCAGCGCCCTGCCCCGCCTGCTGCTGCCGCTG
CTGCTGCTGCCCGCCGCCGGGCCGGCCCAGTTCCACGGGGAGAAGGGCATCTCCATCCCG
GACCACGGCTTCTGCCAGCCCATCTCCATCCCGCTGTGCACGGACATCGCCTACAACCAG
ACCATCATGCCCAACCTTCTGGGCCACACGAACCAGGAGGACGCAGGCCTAGAGGTGCAC
CAGTTCTATCCGCTGGTGAAGGTGCAGTGCTCGCCCGAACTGCGCTTCTTCCTGTGCTCC
ATGTACGCACCCGTGTGCACCGTGCTGGAACAGGCCATCCCGCCGTGCCGCTCTATCTGT
GAGCGCGCGCGCCAGGGCTGCGAAGCCCTCATGAACAAGTTCGGTTTTCAGTGGCCCGAG
CGCCTGCGCTGCGAGCACTTCCCGCGCCACGGCGCCGAGCAGATCTGCGTCGGCCAGAAC
CACTCCGAGGACGGAGCTCCCGCGCTACTCACCACCGCGCCGCCGCCGGGACTGCAGCCG
GGTGCCGGGGGCACCCCGGGTGGCCCGGGCGGCGGCGGCGCTCCCCCGCGCTACGCCACG
CTGGAGCACCCCTTCCACTGCCCGCGCGTCCTCAAGGTGCCATCCTATCTCAGCTACAAG
TTTCTGGGCGAGCGTGATTGTGCTGCGCCCTGCGAACCTGCGCGGCCCGATGGTTCCATG
TTCTTCTCACAGGAGGAGACGCGTTTCGCGCGCCTCTGGATCCTCACCTGGTCGGTGCTG
TGCTGCGCTTCCACCTTCTTCACTGTCACCACGTACTTGGTAGACATGCAGCGCTTCCGC
TACCCAGAGCGGCCTATCATTTTTCTGTCGGGCTGCTACACCATGGTGTCGGTGGCCTAC
ATCGCGGGCTTCGTGCTCCAGGAGCGCGTGGTGTGCAACGAGCGCTTCTCCGAGGACGGT
TACCGCACGGTGGTGCAGGGCACCAAGAAGGAGGGCTGCACCATCCTCTTCATGATGCTC
TACTTCTTCAGCATGGCCAGCTCCATCTGGTGGGTCATCCTGTCGCTCACCTGGTTCCTG
GCAGCCGGCATGAAGTGGGGCCACGAGGCCATCGAGGCCAACTCTCAGTACTTCCACCTG
GCCGCCTGGGCCGTGCCGGCCGTCAAGACCATCACCATCCTGGCCATGGGCCAGATCGAC
GGCGACCTGCTGAGCGGCGTGTGCTTCGTAGGCCTCAACAGCCTGGACCCGCTGCGGGGC
TTCGTGCTAGCGCCGCTCTTCGTGTACCTGTTCATCGGCACGTCCTTCCTCCTGGCCGGC
TTCGTGTCGCTCTTCCGCATCCGCACCATCATGAAGCACGACGGCACCAAGACCGAAAAG
CTGGAGCGGCTCATGGTGCGCATCGGCGTCTTCTCCGTGCTCTACACAGTGCCCGCCACC
ATCGTCATCGCTTGCTACTTCTACGAGCAGGCCTTCCGCGAGCACTGGGAGCGCTCGTGG
GTGAGCCAGCACTGCAAGAGCCTGGCCATCCCGTGCCCGGCGCACTACACGCCGCGCATG
TCGCCCGACTTCACGGTCTACATGATCAAATACCTCATGACGCTCATCGTGGGCATCACG
TCGGGCTTCTGGATCTGGTCGGGCAAGACGCTGCACTCGTGGAGGAAGTTCTACACTCGC
CTCACCAACAGCCGACACGGTGAGACCACCGTGTGAGGGACGCCCCCAGGCCGGAACCGC
GCGGCGCTTTCCTCCGCCCGGGGTGGGGCCCCTACAGACTCCGTATTTTATTTTTTTAAA
TAAAAAACGATCGAAACCATTTCACTTTTAGGTTGCTTTTTAAAAGAGAACTCTCTGCCC
AACACCCCCACAAGGTTTGTAATTAAAACTGTAAATAGTCTTTGTAAATTTAATTATATA
TATTTTCTATTTAAAAGAAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_001466 unedited
GGTCGGATTTTGTATACGACTTCACTATAGGGCGGCCGCGATTCGGCACGAGGGGAGAGA
GGGCAGCAGCGCGCGGTGTCTCCGGCTGCTCAGTCCGACCGCGGCAAGCAAGCGGGCAGG
CGCACCGCCCCCTCCCCCGCCCGGCCTCCCCAACTCTGCGGCCGCGAGTAAAGTTTGCAA
AGAGGCGCGGGAGGCGGCAGCCGCAGCGAGGAGGCGGCGGGGAAGAAGCGCAGTCTCCGG
GTTGGGGGCGGGGGCGGGGGGGGCGCCAAGGAGCCGGGTGGGGGGGCGGNNNNNNNNNTN
TNNNTTNTNNNNNNNNTTTNNTNTTNNTTTTTTTGTNTTTTNTNTTTTTTTTTTTTTTNN
NTTNNNNNNNTTTNTTTNNNNTTGGNNNTTTTNNTTNTTNNTTTTTTTTTTTNTTTTNNN
TTNNTTTTTTTTTTTTTNNTTTTTTTTTTTTTNNTTTTTTNNNTTTTTTTTTTTTTTTTT
TTTTNTTNNTNNTTTNNTTTTTTTTTTTTTTTNTNTTNTTNNTTTTTNNNNNTTNTTTTT
TTTTTTTTTTTTTTTTTTTTNTTTTTTTTTTGGTTTTTTTTTTTTTTTTTTNNNTTTTTC
CTTTTTTTTTNTTTTTTTTTTTNTTTTTTTTTNNTTTTTTTTNTTTTTTTTTTTTTTTTT
TCTTTTTTTTTNTNNTTNTTTTTTTTTTTTTTTNNNNTTNNTTTTNTTTTTTTTTTTNTT
TTTTNTTTTTTTNNTNTTTTTTTTTTTTTTTTTTTTTTTTNTTTNNTTTNNTTTTTTTTT
TTTTTTTTTTTTNNTTTTTTTTTTTTNNNTTTTTTTTNNTTTTTTTTTTTTTTTNTTTTN
TNNTTTNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTNTTTNTTTTTTTTTTTTTNNT
TNNNTTTTTTTTCCTCCTTTTTTTTTTT
>OriGene 3' read for NM_001466 unedited
CGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTCTTTTAAATAGAAAATATAT
ATAATTAAATTTACAAAGACTATTTACAGTTTTAATTACAAACCTTGTGGGGGTGTTGGG
CAGAGAGTTCTCTTTTAAAAAGCAACCTAAAAGTGAAATGGTTTCGATCGTTTTTTATTT
AAAAAAATAAAATACGGAGTCTGTAGGGGCCCCACCCCGGGCGGAGGAAAGCGCCGCGCG
GTTCCGGCCTGGGGGCGTCCCTCACACGGTGGTCTCACCGTGTCGGCTGTTGGTGAGGCG
AGTGTAAAACTTCCTCCACGAGTGCAGCGTCTTGCCCGACCAGATCCAGAAGCCCGACGT
GATGCCCACGATGAGCGTCATGAGGTATTTGATCATGTAGACCGTGAAGTCGGGCGACAT
GCGCGGCGTGTAGTGCGCCGGGCACGGGATGGCCAGGCTCTTGCAGTGCTGGCTCACCCA
CGAGCGCTTCCAGTGCTCGCGGAAGGCCTGCTCGTAAAAGTAGCAAGCGATGACGATGGT
GGGCGGCACTGTGTAGAGCACGGAGAAGACGCCGATGCGCACCATGAGCCCGCTCAGCTT
TTCGGTCTTGGTGCCGTCGTGCTTCATGATGGGTGCGATGCCGAAGAGCGACACGAAGCC
GCCCAGAGGAAGACGTGCCCATGACAAGTACACGAAGAAGCGCGCTAGCACGAACCCCGC
AGGGGTCCAGCCTGTTGAGCCTACGAGCACACGCCGTTCACAAGTCGCCGTCATCTGCCA
TGGCCAGATGGGATTGTCTTGAAGCGGCCGCCCAGGCGGCAGGGGAGTACTGAAGTTGCC
CTCATTGCTCGTGGCCCACTTATGCCGGTTGCGGAACCCGGTGAGGAAGGATGACCCACA
ATGAGCTGCCTGCTGAAAAGTAACCTCTGAAAGGATGGGCCCCCTTTTTTTGGCCCTGCC
CACGGCGGGAACCGTCTGGAAAAGCTGTTGCACCCCCCCTTCGGAACCAAACCG
Restriction Sites NotI-NotI     
ACCN NM_001466
Insert Size 2170 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001466.2, NP_001457.1
RefSeq Size 1983 bp
RefSeq ORF 1698 bp
Locus ID 2535
Cytogenetics 17q21.31
Domains FRI, Frizzled
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway
Gene Summary 'This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]'

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