MCFD2 (AK095006) Human Untagged Clone

CAT#: SC127750

(untagged)-Human cDNA FLJ37687 fis, clone BRHIP2014285

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCFD2
• Synonyms: F5F8D|F5F8D2|LMAN1IP|SDNSF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK095006, the custom clone sequence may differ by one or more nucleotides
  
  
  CCACAGTCCAAAGTCTCATCTGAGACAAGGCAAGTCCCTTCCACCTATGAGCCTGTAAAATCAAAAGCAA
  GCTAGTTACTTCCTAGATACCAACAGGGGTACAGGTATTGATTAAAGACGGCTGTTCCAAATGGGAGAAA
  TTGGCCAAAATAAAGGGGTTACAGGGCCCATGCAAGTCCGAAATCCAGCAGGGCTGTCAAATTTTAAAGT
  TCCAGAATAATCTCCTTTGACTCCAGGTCTCACATCCAGGTCATACTGATGCAAGAAGTGGGTTCCCATG
  GTCTTGGGCAGCTCTGCCCCTGTGGCTTTGTAGGGTACAGCCTCCCTCCTGGCTGCTTTCACGGCTGTTG
  TTCAGTGCCTGCGGCTTTTCCAGGTGCACGGTGCAAGCTGTTGGTGGATCTACCATTCTGGGGTCTGGAG
  GACGGTGGCCCTCTTCTCACAGCTCCACTAGGCAGTGCCCCAGTAGGGACTCTGTGTGGGGGCTCCCACA
  CCACATTCCCCTTCTGCACTGCCCTAGCAGAGGTTCTCTCCCCTGCCGCTGAGAGGGCCTCTCCCCTGCA
  GCAAACGTTTGCCTGGGCATTGAGGCATTTCCATACATCTTCTGAAAACTAGGCGGAGGTTTCCAAATCT
  CAATTCTTGACTTCTGTGCACCTGCAGGCTTAACAGCACATAGAAGCTGCCAAGGCTTGGGGCTTCCACT
  CTGAAGCCACAGCCCGAGCTGTATGTTGGCCCCTTTCAGCCATGGCTGGAGTGGCTGGGACACAAGACAC
  CAAGTCCCTAGGCTGCACACACATGTCAGGGGCTGCCCTGACATGGCCTGGAGACATTTTCCCCATGGTG
  TTGGGGATTAACATTAGGCTCCTTGCTACTTATGCAAATTTCTGCAGCTGGCTTGAATTTCTCCCCAGAA
  AATGGGTTTTTCTTTTCTATTGCATAGTCAGGCTGCAAATTTCCAAACTTTTATGCTTTGCTTCCCTTAT
  TTATAAGGGAATGCCTTTAAAAGCACCCAAGTCACCTGTTGAACACTTTGCTGCTTAGAAATTTCTTCCG
  CTAGTTAACCTAAATCATCTCTCTCAAGTTCAAAGTTTCACAAATCCCTATGGAAGGGGCAAAATGCTGC
  CAGTCTCTTTGCTAAAACATAACAAGAGTCACCTTTACTCCAGTTCCCAACAAGTTCCTCATCTTCATCT
  GAGGCCACCTCAGCCTGGACTTTGTTGTCCATATTGCTATCAGCATTTGGGGCAAAGCCATTCAACAAGT
  CTGTAGGAAGTTCCAAACTTTCCCACATTTTCCTGTTTTCTTCTGAGCCCTCCAAACTGTTCCAGCCTCT
  GCCTGTTACCCAGTTCCAAAGTCACTTCCACATTTTGGGTATTTCTTCAGCAGGTCCCAATCTACTGGTA
  CCAATTTACTGTATTAGTCCGTTTTCACGCTGCTGATAAAGACATACCCGAGACTGGGAAGAAAAAGTGG
  TTTAATTGGACTTAAAGTTCCACATGGCTGGGGAGGCCTCAGAATCATGGTGGGAGGCAAAAGACACTTC
  TTACATTGTGGCAAGAAAAAATGAGGAAGAAGCAAAAGCAGAAACCCCTGATAAACTGATCAGATCTCAT
  GAGACTTATTCACTGTCACGAGAATAGCACGGGAAAGACTGGCCCCCATGATTCAATTACCTCCCCCTGG
  GTCTGTCCCACAACACGTGGGAATTCTGGGAGATACAATTCAAGTTGAGATTTGTGGGGGGACACAACCA
  AACCATATCAGCATCCTTTCAAGAATATTAGATAATTGGAGCTGAGTACTCAGGAACTTGACTGTAGTAG
  AATACCGCTAGTTTCTTAATTTTAATTCACATCACCTGAAAAGTAAAACAACAGGCTTTGCCAAGTGGAT
  GCTTTTCAGTAACAGTGAAGTGGAGTGAATACCAAATGTTTGCCCTGGTGGTTCCTATCTCTTCAGGCAA
  ACATGGTCAGTATTCTGTAAAGTTCCCCTGGCCTAAATGATTACTTGCTCTGGGCAAGTGGATATTTATT
  AGGCTATTTCAAAGCCACAGCATAAGAATGTCAGCCTAGCCACAGAGTCTGAGATTCTGAGTTCAGCCTA
  GCCACAGAGTCTAAGATTCTGTATCCTCTGACATTTTGGAAATGATACACTACTGGCTTAAGTGATGACT
  CTTTCAGATTTTCAGTATTTTATACAACTACTGCCACATCCTTATACTTTATTGCTTTTCTGTCTTCTTC
  AACCTGGGAGAGACCCTGAATTTGAGTGTGTTCTCTAATCAATAGTGGTTTAGCTTTCTTTTCTATTTCA
  CTCGTTTCTAGGGTTTTTTATTTGCAGTTTAGGAACTACTAGGAATGTCAGGACTTTATCAGCAGGGGTA
  AAACTACCACCTGGCCTAGCCTAAGTAGGAAGTGAAAAGATAATTCACCAAACAATGATTAATCAGATAG
  AAGTTCTAGTCAAGAGGGATATTGTTGAAGTTACCTCTTTTAGCCTAGATACATGGATTCTTTTCAAATC
  AGGAAAGATTAGAAAAGGAACCCAAAAAACCCTTTAACAGTGTGAATCTTTATAGTATTTGAAAATGAGA
  AGAAGCAGCAGATTGTAATTTGGTTTATTGGATGTGATGGACGTTCTGTAATAGAAAACCTGAAACGATG
  ATTGAATGGGAAAAAGAGACTACAAAATTTGTCGTAGGATGTATACAGACTTATTTTCTTTATTACAGTA
  TTATAAGAAAACATATGTATTTGTAAAAATGGTTTCCTGTGTCAAGTATTTGTGCAGTCAGAGCTGACTT
  GTAAACTATTCTTGTAATAGCTCATTATTTTGAAAGATTTATATATGATGAATTCTGGATATATGACCAA
  TAAAACTGATGAAGC
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK095006 unedited
  GAATTCGGCACGAGGAGAAATTGGCCAAAATAAAGGGGTTACAGGGCCCATGCAAGTCCG
  AAATCCAGCAGGGCTGTCAAATTTTAAAGTTCCAGAATAATCTCCTTTGACTCCAGGTCT
  CACATCCAGGTCATACTGATGCAAGAAGTGGGTTCCCATGGTCTTGGGCAGCTCTGCCCC
  TGTGGCTTTGTAGGGTACAGCCTCCCTCCTGGCTGCTTTCACGGCTGTTGTTCAGTGCCT
  GCGGCTTTTCCAGGTGCACGGTGCAAGCTGTTGGTGGATCTACCATTCTGGGGTCTGGAG
  GACGGTGGCCCTCTTCTCACAGCTCCACTAGGCAGTGCCCCAGTAGGGACTCTGTGTGGG
  GGCTCCCACACCACATTTCCCTTCTGCACTGCCCTAGCAGAGGTTCTCTCCCCTGCCGCT
  GAGAGGGCCTCTCCCCTGCAGCAAACTTTTGCCTGGGCATTGAGGCATTTCCATACATCT
  TCTGAAACTAGGCGGAGGTTTCCAAATCTCAATTCTTGACTTCTGTGCACCTGCAGGCTT
  AACAGCACATAAAAGCTGCCAGGCTTTGGGGCTTCCACTCTGAACCACAGCCNAGCTGTA
  TTGTGGGCCCTTTCACCCTGGGTTGAAGGGGCTGGGACACAGAACCAAGCCCTAGGCTGA
  CACCCATGTAAAGGGCTGCCCTGCATGCCTGAAACATTTCCCCGGGGTTGGGGGATAAAC
  TTAGGCTCTTGCTCTAAGCAAATCTGGGCCGGGCTGAATTC
  
• Restriction Sites: NotI-NotI
• ACCN: AK095006
• ORF Size: 2885 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK095006.1
• RefSeq Size: 2885
• RefSeq ORF: 2885
• Locus ID: 90411
• Gene Summary: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2016]