Kaiso (ZBTB33) (AK092998) Human Untagged Clone

CAT#: SC127764

(untagged)-Human cDNA FLJ35679 fis, clone SPLEN2019015, moderately similar to Mus musculus zinc finger transcription factor Kaiso mRNA

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZBTB33
• Synonyms: ZNF-kaiso|ZNF348
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK092998, the custom clone sequence may differ by one or more nucleotides
  
  
  TTTATGTCTTCACATATAAAGTCAGTTCATAGTCAAGATCCTTCTGGGGACTCAAAGCTTTATCGTTTAC
  ATCCATGCAGGTCTTTACAAATCAGACAATATGCATATCTTTCCGATAGATCAAGCACTATTCCTGCAAT
  GAAGGATGATGGTATTGGGTATAAGGTTGACACTGGAAAAGAACCTCCAGTAGGGACCACTACATCTACT
  CAGAACAAGCCAATGACCTGGGAAGATATTTTTATTCAGCAGGAAAATGATTCAATTTTTAAACAAAATG
  TAACAGATGGCAGTACTGAGTTTGAATTTATAATACCAGAGTCTTACTAAACTCCTTTGAAATACTAGAA
  AGTTTTGTTTTGGATGATGGGGCAGGGGTTTCAGAAGATCTGTAAAACAAATTAAGGTGCGAACAAGTTA
  ATTTGATCTGCCACATTATCTGAAGGAAGTGTAGTGGGATTTTTGTTGATAATTTTTAGAAGCAAATTTT
  CCTGAAAGTTTTGAGTAGAGGTGAGACCCCCTCCCCAAGTATCTGTTTATATAGTTAGTTTTCAGCTCAT
  TTAAAGGAGGCAAAAATTAAAAGCTTGGAGAGATAGTTTCCTGAATAGAATTTGAAGCAGTCTGAATGTT
  CTTTGAAAATAACTGGAGTTATTAGCATACCCTAGTACATCTTACAGCTTTCCCCTTCCATGTTAGCACT
  TTACTGCTGAATTCTCAATTTTCTTAACATTGAGACAATAAATGTGTGTTTTGTCTTGTATATGGCATAA
  AGAGTAAATAAGTTTTAGAGTTGTTCTGGAAAATGTCAGAATAAGTCAGTACTTGGGTTGTGTAATCTGC
  TAGTCCAAGCGAACAGCAACCTCCTGCTACCCTCCCTCTATGAAAATAGCCATGCAGACAAGTCTCTCAT
  CTGAAGAACAAATTAGATTTAGCTAATTAGAATTAATCCTGGCTTTCATTGCCATAGTCTGTAAAAGACT
  TTGGTGGCTAGACCACTTTATACCTTTGCAGTGTGGTCTCTGGGGGCAAAAAACTAATGAAAACAATCTC
  TGTAATGGCAGATAGGAGGAGATGAAAAGTTCTGTTGCATGGATTTTTAATTCTCTGGCTACCACATAGT
  AGAGAATGGAATGAAGATTTCCTTTTGGCTTCTTAAGGTTAAAAATATTCCCATGAACATGAAAATTTTC
  AAATTTTGAATCTGAAAGCCACCAAATGTATCTTTATGTATAAATCCTTGTAAATGATAGATTCCATGGG
  TGAGACTTTACATATTTTGGGTGGGAGGCTACTGGCATATATTTTTAAATGTTCATATTGCGTAGAATCT
  CCACTAGGAAGTCTTTATTTGAAATAGTTGAATCAGTGATCTAGTATTTTCCTTTCGGCAAGATTTGTTA
  GGTTTTTACCCCTTCTAAAATAAGTTTTATTCCATCTGCAAATTGCTGCAATATTATAGTAATCAGAAAC
  TACATAAGGAATGTTATATAGGCTTGTCAGTTCCCGTTTTTCTTGACAACAATAAATACCACTTTTAAAA
  ATGACACATATTTAAACACTTAGAAAATAAAGTTAACACTTACTGAAGTGCTAGTACTAAACTGTGCTAG
  TACTAAAAGAAAACAGGTTGGAACATACATATAGCCTAGCATTTATAACAGAATTGTTGAACGTCTGTAA
  ATGATTTCTTTTTTTTTTGCAAAGGAAAAAATTGATACTGGAAAAGATTGTTGTGCATAGTTATTAGTCA
  TTTGTAACCTTGCTTAAGTATTTCTTAGTCCAACATAGATATTTTCTTTCTCCTGACCATGTATTTTAAA
  ATATAGTCTATTTCTTGACTTTGAACTTAAAGCTTTAATCATAATTTCTCATGTATACATCGTTCTTCTG
  ATGGTAAGCTGGATTTGAAGGTAGTGGTTTCAGTGTTTCTTAAGTTGGTAGCTGAGGGTATCAGGCATCA
  GTTCATGCAATAATACAAGAAAAAAAATCCTTTGCTTGCCAAGAGGTAGAGTGATGTGCATTTATCTGTT
  TTCTGTTCTGTAAGTCTAGACCTTCAAACCATTTGTAAACTAACCCCTGGGAAATTTGAAATTACCTGAT
  AACTTAAGACTCTGTGATCTCTGGAATCACCATATGTTTCTTTTTTGTGTAGATATTAATAACATTACTC
  TTTGACTATAGTGTGCACTCTGAAATGTACTCAGTGAAAATTTGTTTTGAGTTTCATTAATGCTATTTCA
  CCAGTTAGACATAATTACTTCTACCGATGTGAATGATACGGATGCCGGCAGAGCTTCCAGATCTTTCAGA
  CTCAACTGCTAGGTCAATTAGTTTGTCATAATAAAACTTGGCAGATTCTACAAGTCTATTATGACAAACC
  AGGAACTAATTCTATAATGGAAAACTATCCATTCTGAATAATAGGTATGTAATTATTTGCTGCTGCTGCT
  GTGCTCTGTAAATTCTGAATATGACATTTAAACTCTGTGCCTACTAAAGGTATCTTCTGGAGTTTTTGGG
  AGGAGAGAAACTGGAAAATTAAATTGTATTTTTGCCAGAAGACTCTTACTTGCATGTGTCTCAGGGTCTT
  CAGTTTTTCTATAAGTTTCCATATCCAAAGTTCAGAATTCATGTGAAATACTTCTTTGGGGCAAAAGTCC
  TTCATTCCTGGTATTTATTGGATTGGAAATCTGTAGCAAGATGCTGTTTAAAATTACCATATTGTTTTTT
  TATCTTATACTTAGCTCTCTGGCTATTGAACTTCCTTTTCTTGTTTGAAGTTAGCTTCAAATTTGCTCCT
  ATGCTAAATTACCTGTAAATATTCTGGATAGGAACTACTTGAAATAGTAATTTGTTAAAAGATATGACAA
  AATGAAAATGCTTAAACTACAGAAATTTAAAAATGCCATAACAATCTTGCAAGACTAACTTTAAAATATA
  CTTTAAATGATTATTATGATTTTGGTGGTAACGATCCCCCACACACAACCACTATGAAGAAATAATGCCG
  CATTTTTCCCCCATTGTACC
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK092998 unedited
  CGCGAATTCGGCACCAGCCCTGATGAAGGGGAGGCCATACTTGAGAATGAAATACCAAAA
  ACGTCTGGCAGCGAGATGGCAAACAAACGTATGAAAGTAAAACATGATGATCACTATGAG
  TTAATAGTAGATGGAAGGGTCTATTATATCTGTATTGTATGCAAAAGGTCATATGTCTGT
  CTGACAAGCTTGCGGAGACATTTTAACATTCATTCTTGGGAGAAGAAGTATCCGTGCCGT
  TACTGTGAGAAGGTATTTCCTCTTGCAGAATATCGCACAAAGCATGAAATTCATCACACA
  GGGGAGCGAAGGTATCAGTGTTTGGCCTGTGGCAAATCTTTCATCAACTATCAGTTTATG
  TCTTCACATATAAAGTCAGTTCATAGTCAAGATCCTTCTGGGGACTCAAAGCTTTATCGT
  TTACATCCATGCAGGTCTTTACAAATCAGACAATATGCATATCTTTCCGATAGATCAAGC
  ACTATTCCTGCAATGAAGGATGATGGTATTGAGTATAAGGTTGACACTGGAAAAGAACCT
  CCAGTAGGGACCACTACATCTACTCAGAACAAGCCAATGACCTGNGAAGATATTTTTATT
  CAGCAGGAAAATGATTCAATTTTTAAACAAAATGTAACAGATGGCAGTACTGAGTTTGAA
  TTTATAATACCAGAGTCTTACTAAACTCCTTTGAAATACTAGAAAGTTNNTGTTTGGATG
  ATGG
  
• Restriction Sites: NotI-NotI
• ACCN: AK092998
• ORF Size: 3030 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK092998.1
• RefSeq Size: 3030
• RefSeq ORF: 3030
• Locus ID: 10009
• Gene Summary: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]