ST2 (IL1RL1) (NM_003856) Human Untagged Clone

CAT#: SC127817

IL1RL1 (untagged)-Human interleukin 1 receptor-like 1 (IL1RL1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL1RL1
• Synonyms: DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127817 sequence for NM_003856 edited (data generated by NextGen Sequencing)
  ATGGGGTTTTGGATCTTAGCAATTCTCACAATTCTCATGTATTCCACAGCAGCAAAGTTT
  AGTAAACAATCATGGGGCCTGGAAAATGAGGCTTTAATTGTAAGATGTCCTAGACAAGGA
  AAACCTAGTTACACCGTGGATTGGTATTACTCACAAACAAACAAAAGTATTCCCACTCAG
  GAAAGAAATCGTGTGTTTGCCTCAGGCCAACTTCTGAAGTTTCTACCAGCTGCAGTTGCT
  GATTCTGGTATTTATACCTGTATTGTCAGAAGTCCCACATTCAATAGGACTGGATATGCG
  AATGTCACCATATATAAAAAACAATCAGATTGCAATGTTCCAGATTATTTGATGTATTCA
  ACAGTATCTGGATCAGAAAAAAATTCCAAAATTTATTGTCCTACCATTGACCTCTACAAC
  TGGACAGCACCTCTTGAGTGGTTTAAGAATTGTCAGGCTCTTCAAGGATCAAGGTACAGG
  GCGCACAAGTCATTTTTGGTCATTGATAATGTGATGACTGAGGACGCAGGTGATTACACC
  TGTAAATTTATACACAATGAAAATGGAGCCAATTATAGTGTGACGGCGACCAGGTCCTTC
  ACGGTCAAGGATGAGCAAGGCTTTTCTCTGTTTCCAGTAATCGGAGCCCCTGCACAAAAT
  GAAATAAAGGAAGTGGAAATTGGAAAAAACGCAAACCTAACTTGCTCTGCTTGTTTTGGA
  AAAGGCACTCAGTTCTTGGCTGCCGTCCTGTGGCAGCTTAATGGAACAAAAATTACAGAC
  TTTGGTGAACCAAGAATTCAACAAGAGGAAGGGCAAAATCAAAGTTTCAGCAATGGGCTG
  GCTTGTCTAGACATGGTTTTAAGAATAGCTGACGTGAAGGAAGAGGATTTATTGCTGCAG
  TACGACTGTCTGGCCCTGAATTTGCATGGCTTGAGAAGGCACACCGTAAGACTAAGTAGG
  AAAAATCCAAGTAAGGAGTGTTTCTGA
  
  Clone variation with respect to NM_003856.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003856 unedited
  CGGTCACCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCAAAAACTG
  GAAACTATTCTTAGCTCCGTCACTGACTCCAAGTTCATCCCCTCTGTCTTTCAGTTTGGT
  TGAGATATAGGCTACTCTTCCCAACTCAGTCTTGAAGAGTATCACCAACTGCCTCATGTG
  TGGTGACCTTCACTGTCGTATGCCAGTGACTCATCTGGAGTAATCTCAACAACGAGTTAC
  CAATACTTGCTCTTGATTGATAAACAGAATGGGGTTTTGGATCTTAGCAATTCTCACAAT
  TCTCATGTATTCCACAGCAGCAAAGTTTAGTAAACAATCATGGGGCCTGGAAAATGAGGC
  TTTAATTGTAAGATGTCCTAGACAAGGAAAACCTAGTTACACCGTGGATTGGTATTACTC
  ACAAACAAACAAAAGTATTCCCACTCAGGAAAGAAATCGTGTGTTTGCCTCAGGCCAACT
  TCTGAAGTTTCTACCAGCTGCAGTTGCTGATTCTGGTATTTATACCTGTATTGTCAGAAG
  TCCCACATTCAATAGGACTGGATATGCGAATGTCACCATATATAAAAAACAATCAGATTG
  CAATGTTCCAGATTATTTGATGTATTCAACAGTATCTGGATCAGAAAAAAATTCCAAAAT
  TTATTGTCCTACCATTGACCTCTACAACTGGACAGCACCTCTTGAGTGGTTTAAGAATTG
  TCAGGCTCTTCAGGATCAAGGTACAGGGCGCACAAGTCATTTTTGGTCATTGATAATGTG
  ATGACTGAGGACGCANGTGATTACACCTGNTAATTATACACCATGAAATGGAGCANTNAT
  AGTGTGACGGCGACCAGTCCTTCACGTCAGGATGAGCAAGCTTTTCTCTGTTTCCAGTAT
  CGGAGCCCTGCCAAATGNATAAAGGNAGTGAAAATGGAAAAACCAACCTACTGCTCTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_173459 unedited
  TANGTTGAGTTTTTTTTTTTTTTTTTTGGTTGTGCATTCATTTATTCAGTCAACAAATAT
  TTAGCTGAGCACTGGCTAGCTGCCAGGTATTGCACTAAGGACCCAAAGATGGAAGAGATG
  ATGTCCCTGCCCTCATGGAGCTTGCAGTCGTGTTGAGCAGACTGTCAAACAGATTTAGGT
  AAGGCAATGTGACCAGTGCTATGATACAAACAGGATGCTACAAGAGTACTTGGAAAGTGT
  GTATACTGCAAACTGAGGGCCAAGAAAGGCTCCCTGGAATACGTGGTACCTGAATTACAT
  GGTGAATAACAGATGCAATAAAGAAATGGGCTGAGCTACCAGACTTCCCGTGTGTTCCAT
  GTACCTTAAATACTTTACAAAGTTTAACAATGATAATGTGTGTGGTATGGTTTGGGTCTG
  TGTTCCTGCCCAAATCTCATGCTGAATGGTAATCCCCAGTATTCGAGGTGGAGCCTGGTG
  GGAGGTGATTGGATCATGGGGGTGAGTTCATCATGAATGGTTTAGCACCATCTCTTTGAT
  GCTGTCCTTGCAATAGTGAGTGACTTCTCATGAGATCTGGCTGTTTCAGTGTGGCACCTC
  TCTCTCGCTCCTGCTTTTACTGTGTGAAGTGCCTGCCTTTGCTTTGCCTTCTGCCATGAG
  TAAAGCTCCTGGAGTGTCCCCAGAAGCAGATGCCGCCATGCTTCCCATACAGCCTGCAGA
  ACTGTGAGCCAATTAAACCTCTTTTCATATAAATCACCCAGTCTCAAGTATTTCTTTATA
  TCAATGCAAGAATGGCCTAACAAATGTCTTATTATAAAGTAGCACCCTAGGATTTTCTCA
  CTGAAATAGGCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003856
• ORF Size: 987 bp
• Insert Size: 2650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003856.2, NP_003847.2
• RefSeq Size: 2542
• RefSeq ORF: 987
• Locus ID: 9173
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) has an alternate 5' UTR exon and lacks several 3' terminal exons, and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.