Cyclin A1 (CCNA1) (NM_003914) Human Untagged Clone

CAT#: SC127871

CCNA1 (untagged)-Human cyclin A1 (CCNA1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCNA1
• Synonyms: CT146
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127871 sequence for NM_003914 edited (data generated by NextGen Sequencing)
  ATGGAGACCGGCTTTCCCGCAATCATGTACCCTGGATCTTTTATTGGGGGCTGGGGAGAA
  GAGTATCTCAGCTGGGAAGGACCGGGGCTCCCAGATTTCGTCTTCCAGCAGCAGCCCGTG
  GAGTCTGAAGCAATGCACTGCAGCAACCCCAAGAGTGGAGTTGTGCTGGCTACAGTGGCC
  CGAGGTCCCGATGCTTGTCAGATACTCACCAGAGCCCCGCTGGGCCAGGATCCCCCGCAG
  AGGACAGTGCTAGGGCTGCTAACTGCAAATGGGCAGTACAGGAGGACCTGTGGCCAGGGG
  ATCACAAGAATCAGGTGTTATTCTGGATCAGAAAATGCCTTCCCTCCAGCTGGAAAGAAA
  GCACTCCCTGACTGTGGGGTCCAAGAGCCCCCCAAGCAAGGGTTTGACATCTACATGGAT
  GAACTAGAGCAGGGGGACAGAGACAGCTGCTCGGTCAGAGAGGGGATGGCATTTGAGGAT
  GTGTATGAAGTAGACACCGGCACACTCAAGTCAGACCTGCACTTCCTGCTGGATTTCAAC
  ACAGTTTCCCCTATGCTGGTAGATTCATCTCTCCTCTCCCAGTCTGAAGATATATCCAGT
  CTTGGCACAGATGTGATAAATGTGACTGAATATGCTGAAGAAATTTATCAGTACCTTAGG
  GAAGCTGAAATAAGGCACAGACCCAAAGCACACTACATGAAGAAGCAGCCAGACATCACG
  GAAGGCATGCGCACGATTCTGGTGGACTGGCTGGTGGAGGTTGGGGAAGAATATAAACTT
  CGAGCAGAGACCCTGTATCTGGCTGTCAACTTCCTGGACAGGTTCCTTTCATGTATGTCT
  GTTCTGAGAGGGAAACTGCAGCTCGTAGGAACAGCAGCTATGCTTTTGGCTTCGAAATAT
  GAAGAGATATATCCTCCTGAAGTAGACGAGTTTGTCTATATCACCGATGATACATACACA
  AAACGACAACTGTTAAAAATGGAACACTTGCTTCTGAAAGTTCTAGCTTTTGATCTGACA
  GTACCAACCACCAACCAGTTTCTCCTTCAGTACTTGAGGCGACAAGGAGTGTGCGTCAGG
  ACTGAGAACCTGGCTAAGTACGTAGCAGAGCTGAGTCTACTTGAAGCAGATCCATTCTTG
  AAATATCTTCCTTCACTGATAGCTGCAGCAGCTTTTTGCCTGGCAAACTATACTGTGAAC
  AAGCACTTTTGGCCAGAAACCCTTGCTGCATTTACAGGGTATTCATTAAGTGAAATTGTG
  CCTTGCCTGAGTGAGCTTCATAAAGCGTACCTTGATATACCCCATCGACCTCAGCAAGCA
  ATTAGGGAGAAGTACAAGGCTTCAAAGTACCTGTGTGTGTCCCTCATGGAGCCACCTGCA
  GTTCTTCTTCTACAATAA
  
  Clone variation with respect to NM_003914.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003914 unedited
  GGCGGGTCAAATTTGTATACGACTCATATAGGGCGGCCGCGATTCCCGGGATGACGGGAA
  GAGCGGGGCCCGCTTTGGGGTCCAGGCAGGTTTTGGGGCCTCCTGTCTGGTGGGAGGAGG
  CCGCAGCGCAGCACCCTGCTCGTCACTTGGGATGGAGACCGGCTTTCCCGCAATCATGTA
  CCCTGGATCTTTTATTGGGGGCTGGGGAGAAGAGTATCTCAGCTGGGAAGGACCGGGGCT
  CCCAGATTTCGTCTTCCAGCAGCCCGTGGAGTCTGAAGCAATGCACTGCAGCAACCCCAA
  GAGTGGAGTTGTGCTGGCTACAGTGGCCCGAGGTCCCGATGCTTGTCAGATACTCACCAG
  AGCCCCGCTGGGCCAGGATCCCCCGCAGAGGACAGTGCTAGGGCTGCTAACTGCAAATGG
  GCAGTACAGGAGGACCTGTGGCCAGGGGATCACAAGAATCAGGTGTTATTCTGGATCAGA
  AAATGCCTTCCCTCCAGCTGGAAAGAAAGCACTCCCTGACTGTGGGGTCCAAGAGCCCCC
  CAAGCAAGGGTTTGACATCTACATGGATGAACTAGAGCAGGGGGACAGAGACAGCTGCTC
  GGTCAGAGAGGGGATGGCATTTGAGGATGTGTATGAAGTAGACACCGGCACACTCAAGTC
  AGACCTGCACTTCCTGCTGGATTTCAACACAGTTTCCCCTATGCTGGTAGATTCATCTCT
  CCTCTCCCAGTCTGAAGATATATCCAGTCTTGGCACAGATGTGATAAATGTGACTGAATA
  TGCTGAAGAATTTATCAGTACCTTNAGGAAGCTNGAATAGNGCACAGACCCAAAGCACAC
  TACATGAAGAAGCAGCCAGACATCACGGAAGGCATGCGCACGATTTCTGGTGACT
  
• Restriction Sites: Please inquire
• ACCN: NM_003914
• ORF Size: 1398 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003914.2, NP_003905.1
• RefSeq Size: 1743
• RefSeq ORF: 1398
• Locus ID: 8900
• Domains: cyclin_C, CYCLIN, cyclin
• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Cell cycle, Pathways in cancer, Progesterone-mediated oocyte maturation
• Gene Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).