USP12 (NM_182488) Human Untagged Clone

CAT#: SC127906

USP12 (untagged)-Human ubiquitin specific peptidase 12 (USP12)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP12
• Synonyms: UBH1; USP12L1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_182488 edited
  ATGGAAATCCTAATGACAGTCTCCAAATTCGCCTCCATCTGTACCATGGGCGCCAATGCT
  TCGGCATTAGAGAAAGAGATTGGTCCAGAACAGTTTCCGGTCAATGAGCACTATTTTGGA
  TTAGTCAATTTTGGGAATACCTGCTACTGCAATTCAGTTCTTCAAGCACTTTATTTTTGT
  CGTCCATTTCGGGAAAAAGTTCTTGCGTATAAGAGTCAACCTAGGAAAAAGGAGAGCCTT
  CTTACATGCTTAGCAGATCTCTTCCATAGCATAGCCACTCAGAAGAAAAAGGTTGGAGTA
  ATACCCCCTAAGAAGTTCATCACAAGATTACGGAAAGAAAATGAGCTTTTTGACAACTAC
  ATGCAACAAGATGCCCATGAATTCTTAAATTACCTACTAAATACAATTGCTGATATTTTA
  CAAGAAGAGAGAAAGCAGGAAAAACAAAATGGTCGTTTACCTAATGGTAATATTGATAAT
  GAAAATAATAACAGCACACCAGACCCAACGTGGGTTCATGAGATTTTTCAGGGAACATTA
  ACTAATGAAACCAGATGTCTTACTTGTGAAACTATAAGCAGCAAAGATGAAGATTTTTTA
  GACCTTTCTGTTGACGTGGAACAAAATACATCAATTACTCACTGCTTAAGGGGTTTCAGC
  AACACAGAAACTCTGTGCAGTGAATACAAGTATTACTGTGAAGAGTGTCGCAGCAAACAG
  GAAGCACACAAACGGATGAAAGTTAAAAAACTGCCCATGATTCTAGCTCTACACCTGAAG
  AGATTTAAATATATGGATCAACTTCATCGATATACAAAACTCTCTTACCGGGTAGTTTTT
  CCTTTAGAACTTCGTCTGTTTAACACTTCAGGTGATGCCACCAATCCAGACAGAATGTAC
  GACCTTGTTGCTGTTGTGGTTCACTGTGGAAGTGGTCCCAATCGAGGCCATTATATTGCA
  ATAGTTAAGAGTCATGATTTTTGGTTGTTGTTTGATGACGACATTGTAGAAAAAATAGAT
  GCACAAGCTATTGAAGAATTCTACGGGTTGACATCAGATATCTCAAAGAACTCTGAGTCT
  GGTTACATCCTTTTCTATCAGTCTCGGGACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182488 unedited
  TCACATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCAGCG
  GCGGCCCAGCGGGCTCGGTGGTTGGGTCCGCGGCGGCTCGGGGTCCGCCCGCGGGCTGCG
  GTGCGAGCGGGCGGCCCGGCTCCCCTCCTCCCCCGCCCGCCGCCGCCGCTGTGATTGGGT
  GGAAGATGGCGCTGGCCGGATGGAAATCCTAATGACAGTCTCCAAATTCGCCTCCATCTG
  TACCATGGGCGCCAATGCTTCGGCATTAGAGAAAGAGATTGGTCCAGAACAGTTTCCGGT
  CAATGAGCACTATTTTGGATTAGTCAATTTTGGGAATACCTGCTACTGCAATTCAGTTCT
  TCAAGCACTTTATTTTTGTCGTCCATTTCGGGAAAAAGTTCTTGCGTATAAGAGTCAACC
  TANGAAAAAGGAGAGCCTTCTTACATGCTTACCAGATCTCTTCCATAGCATAGCCCACTC
  AGAAGAAAAAGGTTGGAGTAATACCCCCTAAGAAGTTCATCACAAGATTACCGGGAAAGA
  AATGAGCTTTTTTGACCACTACTGGCCAACAGGATGCCCCATGGAATTTCTTAAATTTAC
  CTTACTAAAATACCAATTGCCTGGATATTTTTACCAAGAAAGAATAGAAAAGCCCGGAAA
  AACCACAAAATGGGTCGGTTTTACCTAAAGGGGGAAAAATTTGGGTAAAGGGAAAAATTA
  ATTAACAGGCCCCCCCCCGGAACCCCAAGGTGGGGTGTTCAATGGAGAAATTTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_182488 unedited
  TGCGTGTGAAATCCGGGCCAGGAGAGGCACTGGNNNNNNCGGGAGGGATGCCACCCGGGA
  TCTGTTCAGGAAACAGCTATGATCGCGGCCGCAATCTAGAGTCGAGTTTTTTGGTTTTTT
  TTTTTTTTTTTTTTTTTCACAAATAAACCAACTTTAATAGATATTATTTTGTATTTATAT
  AGTGCCTTCTTCAAGAACCTTAAATGCTTTACAGACATTATCTCTAATTAATCCCCACAA
  CAACCCTGTGAGGTAGGTATTACTCCCATTTTACAAGACAGGGAGACTGAAGCACAGAGA
  GGTTAAGTGACTTGCCCAAGGTCACACAGTTAAATTCACTGAAAAGCCAGGACATGAGCG
  CTTTAGCCTCCCAGCTCCCAGCCAAATACCTCATGATAGAATCTTTAATAAAAAGTGTTT
  TTAAAGAAAGTATCAAGAGTAGTTATGTTATGAAAATGAGGTCTTTCTACTGCCATCAAG
  GAAAGAAAAAACCCTATACTGATGGTTAGAGGCCCCAAGACCCACATAATACAACATTTC
  CCTCTTTCCCTGGTCCCAAGCCTCCCCGGTTTCCGGCTTAAAAAAACCTTTTAAGGGGGA
  AATTTTCAAAACGAAACCCCGGGGCTCTAAAAGAGGGGATTTACTTTAGAATAATTCACT
  TTTAGTCACAATAATTTAAAGAAATTTTTATCCCCATTTACCAAAATATGGGACAGCCTT
  CCCAACAATTTTGTACATAGTTTCCACGGCATCCACCCCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_182488
• ORF Size: 1113 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_182488.1, NP_872294.1
• RefSeq Size: 2392
• RefSeq ORF: 1113
• Locus ID: 219333
• Protein Families: Druggable Genome, Protease
• Gene Summary: Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProtKB/Swiss-Prot Function]