PAFAH (PLA2G7) (NM_005084) Human Untagged Clone

CAT#: SC127916

PLA2G7 (untagged)-Human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLA2G7
• Synonyms: LDL-PLA2; LP-PLA2; PAFAD; PAFAH
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127916 sequence for NM_005084 edited (data generated by NextGen Sequencing)
  ATGGTGCCACCCAAATTGCATGTGCTTTTCTGCCTCTGCGGCTGCCTGGCTGTGGTTTAT
  CCTTTTGACTGGCAATACATAAATCCTGTTGCCCATATGAAATCATCAGCATGGGTCAAC
  AAAATACAAGTACTGATGGCTGCTGCAAGCTTTGGCCAAACTAAAATCCCCCGGGGAAAT
  GGGCCTTATTCCGTTGGTTGTACAGACTTAATGTTTGATCACACTAATAAGGGCACCTTC
  TTGCGTTTATATTATCCATCCCAAGATAATGATCGCCTTGACACCCTTTGGATCCCAAAT
  AAAGAATATTTTTGGGGTCTTAGCAAATTTCTTGGAACACACTGGCTTATGGGCAACATT
  TTGAGGTTACTCTTTGGTTCAATGACAACTCCTGCAAACTGGAATTCCCCTCTGAGGCCT
  GGTGAAAAATATCCACTTGTTGTTTTTTCTCATGGTCTTGGGGCATTCAGGACACTTTAT
  TCTGCTATTGGCATTGACCTGGCATCTCATGGGTTTATAGTTGCTGCTGTAGAACACAGA
  GATAGATCTGCATCTGCAACTTACTATTTCAAGGACCAATCTGCTGCAGAAATAGGGGAC
  AAGTCTTGGCTCTACCTTAGAACCCTGAAACAAGAGGAGGAGACACATATACGAAATGAG
  CAGGTACGGCAAAGAGCAAAAGAATGTTCCCAAGCTCTCAGTCTGATTCTTGACATTGAT
  CATGGAAAGCCAGTGAAGAATGCATTAGATTTAAAGTTTGATATGGAACAACTGAAGGAC
  TCTATTGATAGGGAAAAAATAGCAGTAATTGGACATTCTTTTGGTGGAGCAACGGTTATT
  CAGACTCTTAGTGAAGATCAGAGATTCAGATGTGGTATTGCCCTGGATGCATGGATGTTT
  CCACTGGGTGATGAAGTATATTCCAGAATTCCTCAGCCCCTCTTTTTTATCAACTCTGAA
  TATTTCCAATATCCTGCTAATATCATAAAAATGAAAAAATGCTACTCACCTGATAAAGAA
  AGAAAGATGATTACAATCAGGGGTTCAGTCCACCAGAATTTTGCTGACTTCACTTTTGCA
  ACTGGCAAAATAATTGGACACATGCTCAAATTAAAGGGAGACATAGATTCAAATGCAGCT
  ATTGATCTTAGCAACAAAGCTTCATTAGCATTCTTACAAAAGCATTTAGGACTTCATAAA
  GATTTTGATCAGTGGGACTGCTTGATTGAAGGAGATGATGAGAATCTTATTCCAGGGACC
  AACATTAACACAACCAATCAACACATCATGTTACAGAACTCTTCAGGAATAGAGAAATAC
  AATTAG
  
  Clone variation with respect to NM_005084.3
  1136 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005084 unedited
  GTTCGAATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACCAGGCCAGAG
  CTGCTCGGCCCGCAGCCAGGGGGACAGCGGCTGGTCGGAGGCTCGCAGTGCTGTCGGCGA
  GAAGCAGTCGGGTTTGGAGCGCTTGGGTCGCGTTGGTGCGCGGTGGAACGCGCCCAGGGA
  CCCCAGTTCCCGCGAGCAGCTCCGCGCCGCGCCTGAGAGACTAAGCTGAAACTGCTGCTC
  AGCTCCCAAGATGGTGCCACCCAAATTGCATGTGCTTTTCTGCCTCTGCGGCTGCCTGGC
  TGTGGTTTATCCTTTTGACTGGCAATACATAAATCCTGTTGCCCATATGAAATCATCAGC
  ATGGGTCAACAAAATACAAGTACTGATGGCTGCTGCAAGCTTTGGCCAAACTAAAATCCC
  CCGGGGAAATGGGCCTTATTCCGTTGGTTGTACAGACTTAATGTTTGATCACACTAATAA
  GGGCACCTTCTTGCGTTTATATTATCCATCCCAAGATAATGATCGCCTTGACACCCTTTG
  GATCCCAAATAAAGAATATTTNTTGGGGTCTTAGCANATTTCTTGGAACACACTGGCTTA
  TGGGCAACATTTTGAGGTTACTCTTTGGTTCAATGACAACTCCTGCAAACTGGGATTCCC
  CTCTGNAGCCTGGTGAAAATATCCACTTGGTGNNTTTTCTCATGGNNCTTGNNGCATTCA
  NGACACTTTATTCTGCTATTGGCATTGACCTGNCATCTCATGGGTTTATAGNTGCTGCTG
  TAAACACAGAGATAGATCTGCATCTGCAACTTACTATTTCAGGGACAATCTGCTGCAGAA
  TAGGGGACCANAAAGNNNTTTTTGGNGGGTNTTTTTTTTTTTANNNCCCTCTTTTTTTTN
  NNNNNNNAANNANNNNANNNCCCTCCCCTCTCTTCGGCTGGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005084 unedited
  AGCACTGGGGGNAGGGGTCACAGGGNATGCCACCCGGGCACTGTTCAGGAAAAGCTATGA
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAAAACCTATTTTAATC
  CTAATTGTATTTCTCTATTCCTGAAGAGTTCTGTAACATGATGTGTTGATTGGTTGTGTT
  AATGTTGGTCCCTGNAATAAGATTCTCATCATCTCCTTCAATCAAGCAGTCCCACTGATC
  AAAATCTTTAGAAGTCCTAAATGCTTTTGTAAGAATGCTAATGAAGCTTTGTTGCTAAGA
  TCAATAACTGCATTGGAATCCATGTCTCCCTTTAATTTGAGCATGTGGCCAAATTTTTTT
  GCCAGTTGCAAAGTGGAATTCAGCAAAATTCGGGTGAACGGAACCCCGGATGGGAACCAC
  CTTTTTTTCTTTACACGGGGAAAACAAATTTTTCCTTTTTTGGGAAATAACCCGGAATTG
  GGAAAATTTCCAAGTTGGAAAAAAAAAAGGGCGGGGGAAATTTGGGGAAAAAACCTTCCA
  CCCCCGTGGAAAACTTCTTGCCTCCCGGGGGGAAACCCCAACCGGAAATTTCGGTTTTTC
  CAAAAAAACTCGAAAAAACGTGGGTTCCCCCCCAAAAAAGGGCCCCAAATCGGCGGTTTT
  TTTTTCCCCAAAAAAAGAGACCCTCTCATTGGTGCCCCAAACAAAAATTTTTAATCTAAG
  GGGGTTCTTTCAGGGGGTTTTCTCGGGAGAAAGGGGTGGAAAAAAAAAACAGGAAGGCTT
  GGGGGAAATATCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005084
• ORF Size: 1326 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005084.2, NP_005075.2
• RefSeq Size: 1561
• RefSeq ORF: 1326
• Locus ID: 7941
• Domains: PAF-AH_p_II
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Ether lipid metabolism, Metabolic pathways
• Gene Summary: The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2009]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.