TPSG1 (NM_012467) Human Untagged Clone

CAT#: SC127922

TPSG1 (untagged)-Human tryptase gamma 1 (TPSG1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TPSG1
• Synonyms: PRSS31; TMT; trpA
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012467 edited
  CCATGGCCCTTGGGGCCTGTGGCCTCCTGCTGCTCCTGGCTGTGCCCGGTGTGTCCCTCA
  GGACTTTGCAGCCAGGGTGTGGCCGGCCGCAGGTTTCGGATGCAGGCGGCCGGATCGTGG
  GGGGTCACGCTGCCCCGGCCGGCGCATGGCCATGGCAGGCCAGCCTCCGCCTGCGGAGGA
  TGCACGTGTGCGGCGGGTCACTGCTCAGCCCCCAGTGGGTGCTCACAGCTGCCCACTGCT
  TCTCCGGGTCCCTGAACTCATCCGACTACCAGGTGCACCTGGGGGAACTGGAGATCACTT
  TGTCTCCCCACTTCTCCACCGTGAGGCAGATCATCCTGCACTCCAGCCCCTCAGGACAGC
  CGGGGACCAGCGGGGACATCGCCCTGGTGGAGCTCAGTGTCCCCGTGACCCTCTCCAGCC
  GGATCCTGCCCGTCTGCCTCCCGGAGGCCTCAGATGACTTCTGCCCTGGGATCCGGTGCT
  CGGTGACCGGCTGGGGCTATACGCGGGAGGGAGAGCCTCTGCCACCCCCGTACAGCCTGC
  GGGAGGTGAAAGTCTCCGTGGTGGACACAGAGACCTGCCGCCGGGACTATCCCGGCCCCG
  GGGGCAGCATCCTTCAGCCCGACATGCTGTGTGCCCGGGGCCCCGGGGATGCCTGCCAGG
  ACGACTCCGGGGGGCCTCTGGTCTGCCAGGTGAACGGTGCCTGGGTGCAGGCTGGCATTG
  TGAGCTGGGGTGAGGGCTGCGGCCGCCCCAACAGGCCGGGAGTCTACACTCGTGTCCCTG
  CCTACGTGAACTGGATCCGCCGCCACATCACAGCATCAGGGGGCTCAGAGTCTGGGTACC
  CCAGGCTCCCCCTCCTGGCTGGCTTCTTCCTCCCCGGCCTCTTCCTTCTGCTAGTCTCCT
  GTGTCCTGCTGGCCAAGTGCCTGCTGCACCCATCTGCGGATGGTACTCCCTTCCCCGCCC
  CTGACTGATGGCAGGAATCCAAGTGCA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012467 unedited
  NNNGGTTCAGTTCAATTTTGTATACGACTCACTATAGGCGGCCGCGTATTCGCCCTTCCA
  TGGCCCTTGGGGCCTGTGGCCTCCTGCTGCTCCTGGCTGTGCCCGGTGTGTCCCTCAGGA
  CTTTGCAGCCAGGGTGTGGCCGGCCGCAGGTTTCGGATGCAGGCGGCCGGATCGTGGGGG
  GTCACGCTGCCCCGGCCGGCGCATGGCCATGGCAGGCCAGCCTCCGCCTGCGGAGGATGC
  ACGTGTGCGGCGGGTCACTGCTCAGCCCCCAGTGGGTGCTCACAGCTGCCCACTGCTTCT
  CCGGGTCCCTGAACTCATCCGACTACCAGGTGCACCTGGGGGAACTGGAGATCACTTTGT
  CTCCCCACTTCTCCACCGTGAGGCAGATCATCCTGCACTCCAGCCCCTCAGGACAGCCGG
  GGACCAGCGGGGACATCGCCCTGGTGGAGCTCAGTGTCCCCGTGACCCTCTCCAGCCGGA
  TCCTGCCCGTCTGCCTCCCGGAGGCCTCAGATGACTTCTGCCCTGGGATCCGGTGCTCGG
  TGACCGGCTGGGGCTATACGCGGGAGGGAGAGCCTCTGCCACCCCCGTACAGCCTGCGGG
  AGGTGAAAGTCTCCGTGGTGGACACAGAGACCTGCCGCCGGGACTATCCCGGCCCCGGGG
  GCAGCATCCTTCAGCCCGACATGCTGTGTGCCCGGNGCCCCGGNGATGCCTGCCAGGACG
  ACTCCGGGGGGCCTCTGGTCTGCCAGGTGAACGGTGCCTGGGTGCAGGCTGGCATTGTGA
  GCTGGGGTGAGGGCTGCGGCCGCCCCAACAGCCGGGAGTCTACACTCGTGTCCCTGCCTA
  CGTGAACTGGATCCGCCG
  
• Restriction Sites: Please inquire
• ACCN: NM_012467
• ORF Size: 966 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012467.2, NP_036599.2
• RefSeq Size: 1124
• RefSeq ORF: 966
• Locus ID: 25823
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]