Caspase 14 (CASP14) (NM_012114) Human Untagged Clone

CAT#: SC127955

CASP14 (untagged)-Human caspase 14, apoptosis-related cysteine peptidase (CASP14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CASP14
• Synonyms: ARCI12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012114, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCAATCCGCGGTCTTTGGAAGAGGAGAAATATGATATGTCAGGTGCCCGCCTGGCCCTAATACTGT
  GTGTCACCAAAGCCCGGGAAGGTTCCGAAGAAGACCTGGATGCTCTGGAACACATGTTTCGGCAGCTGAG
  ATTCGAAAGCACCATGAAAAGAGACCCCACTGCCGAGCAATTCCAGGAAGAGCTGGAAAAATTCCAGCAG
  GCCATCGATTCCCGGGAAGATCCCGTCAGTTGTGCCTTCGTGGTACTCATGGCTCACGGGAGGGAAGGCT
  TCCTCAAGGGAGAAGATGGGGAGATGGTCAAGCTGGAGAATCTCTTCGAGGCCCTGAACAACAAGAACTG
  CCAGGCCCTGCGAGCTAAGCCCAAGGTGTACATCATACAGGCCTGTCGAGGAGAACAAAGGGACCCCGGT
  GAAACAGTAGGTGGAGATGAGATTGTGATGGTCATCAAAGACAGCCCACAAACCATCCCAACATACACAG
  ATGCCTTGCACGTTTATTCCACGGTAGAGGGATACATCGCCTACCGACATGATCAGAAAGGCTCATGCTT
  TATCCAGACCCTGGTGGATGTGTTCACGAAGAGGAAAGGACATATCTTGGAACTTCTGACAGAGGTGACC
  CGGCGGATGGCAGAAGCAGAGCTGGTTCAAGAAGGAAAAGCAAGGAAAACGAACCCTGAAATCCAAAGCA
  CCCTCCGGAAACGGCTGTATCTGCAGTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012114 unedited
  NGGTCAGACAGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCGCCCTTACTCACA
  ACCAAGGNAGAAATGAGCAATCCGCGGTCTTTGGAAGAGGAGAAATATGATATGTCAGGT
  GCCCGCCTGGCCCTAATACTGTGTGTCACCAAAGCCCGGGAAGGTTCCGAAGAAGACCTG
  GATGCTCTGGAACACATGTTTCGGCAGCTGAGATTCGAAAGCACCATGAAAAGAGACCCC
  ACTGCCGAGCAATTCCAGGAAGAGCTGGAAAAATTCCAGCAGGCCATCGATTCCCGGGAA
  GATCCCGTCAGTTGTGCCTTCGTGGTACTCATGGCTCACGGGAGGGAAGGCTTCCTCAAG
  GGAGAAGATGGGGAGATGGTCAAGCTGGAGAATCTCTTCGAGGCCCTGAACAACAAGAAC
  TGCCAGGCCCTGCGAGCTAAGCCCAAGGTGTACATCATACAGGCCTGTCGAGGAGAACAA
  AGGGACCCCGGTGAAACAGTAGGTGGAGATGAGATTGTGATGGTCATCAAAGACAGCCCA
  CAAACCATCCCAACATACACAGATGCCTTGCACGTTTATTCCACGGTAGAGGGATACATC
  GCCTACCGACATGATCAGAAAGGCTCATGCTTTATCCAGACCCTGGTGGATGTGTTCACG
  AAGAGGAAAGGACATATCTTGGAACTTCTGACAGAGGTGACCCGGCGGATGGCAGAAGCA
  GAGCTGGTTCAAGAAGGAAAAGCAAGGAAAACGAACCCTGAAATCCAAAGCACCCTCCGG
  AAACGGCTGTATCTGCAGTAGAAGGGCGAATTCAGATCTGGTACCGATATCAAGCTTGTC
  GACTCTAGATTTGCGCCCGCGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCNT
  GT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012114 unedited
  CATAGACCATCGGCTGATGGCAACTTNCCAGGNCCAGGNANGAGCACTGGGGNAGGGGTA
  CACAGGGNATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAG
  AGTCGACAAGCTTGATATCGGTACCAGATCTGAATTCGCCCTTCTACTGCAGATACAGCC
  GTTTCCGGAGGGTGCTTTGGATTTCAGGGTTCGTTTTCCTTGCTTTTCCTTCTTGAACCA
  GCTCTGCTTCTGCCATCCGCCGGGTCACCTCTGTCAGAAGTTCCAAGATATGTCCTTTCC
  TCTTCGTGAACACATCCACCAGGGTCTGGATAAAGCATGAGCCTTTCTGATCATGTCGGT
  AGGCGATGTATCCCTCTACCGTGGAATAAACGTGCAAGGCATCTGTGTATGTTGGGATGG
  TTTGTGGGCTGTCTTTGATGACCATCACAATCTCATCTCCACCTACTGTTTCACCGGGGT
  CCCTTTGTTCTCCTCGACAGGCCTGTATGATGTACACCTTGGGCTTAGCTCGCAGGGCCT
  GGCAGTTCTTGTTGTTCAGGGCCTCGAAGAGATTCTCCAGCTTGACCATCTCCCCATCTT
  CTCCCTTGAGGAAGCCTTCCCTCCCGTGAGCCATGAGTACCACGAAGGCACAACTGACGG
  GATCTTCCCGGGAATCGATGGCCTGCTGGAATTTTTCCAGCTCTTCCTGGAATTGCTCGG
  CAGTGGGGTCTCTTTTCATGGTGCTTTCGAATCTCAGCTGCCGAAACTGTGTTCCAGAGC
  ATCCAGGTCTTCTTCCGAACCTTCCCGGGCTTTGGTGACACACAGTATTAGGGCCAGGCG
  GGCACCTGACATATCATATTTCTCCTCTTCCAAAGACCCGGATTGCTCATTA
  
• Restriction Sites: Please inquire
• ACCN: NM_012114
• ORF Size: 729 bp
• Insert Size: 800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012114.1, NP_036246.1
• RefSeq Size: 777
• RefSeq ORF: 729
• Locus ID: 23581
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]