PTPN7 (NM_080588) Human Untagged Clone

CAT#: SC128004

PTPN7 (untagged)-Human protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN7
• Synonyms: BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_080588, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGCCTCCTTCTGGCCAATCAGGCAGGCCAGAGAACAGCAGCGGAGGGCCCTGTCTTTCAGGCAGA
  CCTCATGGCTGAGTGAGCCTCCCCTGGGCCCAGCACCCCACCTCAGCATGGTCCAAGCCCATGGGGGGCG
  CTCCAGAGCACAGCCGTTGACCTTGTCTTTGGGGGCAGCCATGACCCAGCCTCCGCCTGAAAAAACGCCA
  GCCAAGAAGCATGTGCGACTGCAGGAGAGGCGGGGCTCCAATGTGGCTCTGATGCTGGACGTTCGGTCCC
  TGGGGGCCGTAGAACCCATCTGCTCTGTGAACACACCCCGGGAGGTCACCCTACACTTTCTGCGCACTGC
  TGGACACCCCCTTACCCGCTGGGCCCTTCAGCGCCAGCCACCCAGCCCCAAGCAACTGGAAGAAGAATTC
  TTGAAGATCCCTTCAAACTTTGTCAGCCCCGAAGACCTGGACATCCCTGGCCACGCCTCCAAGGACCGAT
  ACAAGACCATCTTGCCAAATCCCCAGAGCCGTGTCTGTCTAGGCCGGGCACAGAGCCAGGAGGACGGAGA
  TTACATCAATGCCAACTACATCCGAGGCTATGACGGGAAGGAGAAGGTCTACATTGCCACCCAGGGCCCC
  ATGCCCAACACTGTGTCGGACTTCTGGGAGATGGTGTGGCAAGAGGAAGTGTCCCTCATTGTCATGCTCA
  CTCAGCTCCGAGAGGGCAAGGAGAAATGTGTCCACTACTGGCCCACAGAAGAGGAAACCTATGGACCCTT
  CCAGATCCGCATCCAGGACATGAAAGAGTGCCCAGAATACACTGTGCGGCAGCTCACCATCCAGTACCAG
  GAAGAGCGCCGGTCAGTAAAGCACATCCTCTTTTCGGCCTGGCCAGACCATCAGACACCAGAATCAGCTG
  GGCCCCTGCTGCGCCTAGTGGCAGAGGTGGAGGAGAGCCCGGAGACAGCCGCCCACCCCGGGCCTATCGT
  AGTCCACTGCAGTGCAGGGATTGGCCGGACGGGCTGCTTCATCGCCACGCGAATTGGCTGTCAACAGCTG
  AAAGCCCGAGGAGAAGTGGACATTCTGGGTATTGTGTGCCAACTGCGGCTAGACAGAGGGGGGATGATCC
  AGACGGCAGAGCAGTACCAGTTCCTGCACCACACTTTGGCCCTGTATGCAGGCCAGCTGCCTGAGGAACC
  CAGCCCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_080588 unedited
  TTNNNGNCCTTGTCACATTTGTATACGACTCACTATAGGCGGCACGCGATTCTTCTTCCG
  TTGCTTGGGGCTGGGTGGCTGGCGCTGAAGGGCCCAGCGGGTAAGGGGGTGTCCAGCAGT
  GCGCAGAAAGTGTAGGGTGACCTCCCGGGGTGTGTTCACAGAGCAGATGGGTTCTACGGC
  CCCCAGGGACCGAACGTCCAGCATCAGAGCCACATTGGAGCCCCGCCTCTCCTGCAGTCG
  CACATGCTTCTTGGCTGGCGTTTTTTCAGGCGGAGGCTGGGTCATGGCTGCCCCCAAAGA
  CAAGGTCAACGGCTGTGCTCTGGAGCGCCCCCCATGGGCTTGGACCATGCTGAGGTGGGG
  TGCTGGGCCCAGGGGAGGCTCACTCAGCCATGAGGTCTGCCTGAAAGACAGGGCCCTCCG
  CTGCTGTTCTCTGGCCTGCCTGATTGGCCAGAAGGAGGCTCCCATGCCAGGCCAGGTTTG
  CACTCTGTTTTCACTGGGGCGTCTTCTGTTCCCCAAGAGGTGGCCTCATTTTCACTAAGG
  GAAGGACAGGATCTATTTGGTGGGACCCAGGGCAGAAGGCAGTCTCGGGGTAGAGTAACG
  GCAAGATAAAGGGTAGAGATTGTGGATGAAGATAGGAAAGAATCCAGAAGGAGGAAAAGA
  GAGAGGGGAGAGAGGCCACACACCAGAGTACACAGGGCTCTGAGCAGGTCCAAGTGGGAT
  GAGGCAAGGGAGGAAACAGAAAATATGTGTTCTCTAGGACGGAAGGGAGAAAGCACGCAG
  GAGCCATCTCTGAGCTAACCAGTGGGCCTTCCCCTGAACAGAGAATGGATGCCTCCANCA
  GTGTTG
  
• Restriction Sites: Please inquire
• ACCN: NM_080588
• ORF Size: 1200 bp
• Insert Size: 2700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_080588.1, NP_542155.1
• RefSeq Size: 3263
• RefSeq ORF: 1200
• Locus ID: 5778
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) lacks an exon from the 5' end and contains an alternate 5' segment which includes an AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.