PCPTP1 (PTPRR) (NM_130846) Human Untagged Clone

CAT#: SC128013

PTPRR (untagged)-Human protein tyrosine phosphatase, receptor type, R (PTPRR), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRR
• Synonyms: EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128013 sequence for NM_130846 edited (data generated by NextGen Sequencing)
  ATGATTCTTTACAGATTAAAAGAAAGATTTCAGCTTTCCTTAAGACAAGACAAAGAGAAA
  AACCAGGAGATCCACCTATCGCCCATCACATTACAGCCAGCACTGTCCGAGGCAAAGACA
  GTCCACAGCATGGTCCAACCTGAGCAGGCCCCAAAGGTACTGAATGTTGTCGTGGACCCT
  CAAGGCCGAGGTGCTCCTGAGATCAGAGCTACCACCGCTACCTCTGTTTGCCCTTCTCCT
  TTCAAAATGAAGCCCATAGGACTTCAAGAGAGAAGAGGGTCCAACGTATCTCTTACATTG
  GACATGAGTAGCTTGGGGAACATTGAACCCTTTGTGTCTATACCAACACCACGGGAGAAG
  GTAGCAATGGAGTATCTGCAGTCAGCCAGCCGAATTCTCACAAGGTCTCAGCTGAGGGAC
  GTCGTGGCAAGTTCACATTTACTCCAAAGTGAATTCATGGAAATACCAATGAACTTTGTG
  GATCCCAAAGAAATTGATATTCCGCGTCATGGAACTAAAAATCGCTATAAGACCATTTTA
  CCAAATCCCCTCAGCAGAGTGTGTTTAAGACCAAAAAATGTAACCGATTCATTGAGCACC
  TACATTAATGCTAATTATATTAGGGGCTACAGTGGCAAGGAGAAAGCCTTCATTGCCACG
  CAGGGCCCCATGATCAACACCGTGGATGATTTCTGGCAGATGGTTTGGCAGGAAGACAGC
  CCTGTGATTGTTATGATCACAAAACTCAAAGAAAAAAATGAGAAATGTGTGCTATACTGG
  CCGGAAAAGAGAGGGATATATGGAAAAGTTGAGGTTCTGGTTATCAGTGTAAATGAATGT
  GATAACTACACCATTCGAAACCTTGTCTTAAAGCAAGGAAGCCACACCCAACATGTGAAG
  CATTACTGGTACACCTCATGGCCTGATCACAAGACTCCAGACAGTGCCCAGCCCCTCCTA
  CAGCTCATGCTGGATGTAGAAGAAGACAGACTTGCTTCCCAGGGCCGAGGGCCTGTGGTT
  GTCCACTGCAGTGCAGGAATAGGTAGAACAGGGTGTTTTATTGCTACATCCATTGGCTGT
  CAACAGCTGAAAGAAGAAGGAGTTGTGGATGCACTAAGCATTGTCTGCCAGCTTCGTATG
  GATAGAGGTGGAATGGTGCAAACCAGTGAGCAGTATGAATTTGTGCACCATGCTCTGTGC
  CTGTATGAGAGCAGACTTTCAGCAGAGACTGTCCAGTGA
  
  Clone variation with respect to NM_130846.2
  206 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130846 unedited
  CGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGAACTCTCTTACCTATGAACC
  AGGTAGTTTCCAAGAGAGACGCTGAGGGATGTTTAGAAAGCCTGGGACCTGCAGATGCCA
  TGTCAGGCACGCTTGCTCCTGCATAGGAGACTAAATAATCTCGATATATAAGGATGGCAG
  TCTGTTGTCTTAGATCAGTTTGAGAAGCAGCTCTGGCAGCGGGGGGTGTAGGTGTGTTGC
  ACTACACTGAATGGAATAAGGCTAAAAATATGTTTAGTGTCTGATAAGAACGCCAGTTTT
  CTCAAGCTCTCATTTAACGTCGGACTTTCTGTTTTGCTTTTAAAGAAAAATGTTTTACAA
  GGGCAGCATGAAGCGGACAAAATCTGGAGCAAAGAAGGATTTTATGCTGTTGTCATTTTT
  CTCAGCATCTTTGTTATTATAGTAACGTGTTTGATGATTCTTTACAGATTAAAAGAAAGA
  TTTCAGCTTTCCTTAAGACAAGACAAAGAGAAAAACCAGGAGATCCACCTATCGCCCATC
  ACATTACAGCCAGCACTGTCCGAGGCAAAGACAGTCCACAGCATGGTCCAACCTGAGCAG
  GCCCCANAGGTACTGAATGTTGTCGTGGACCCTCAANGCCGAGTGCTCCTGAGATCAGAG
  CTACCACCGCTACCTCTGTTTGCCCTTCTCCTTTCAAATGAAGCCCATNNAGACTCAGAG
  AGAGAGGGTCCACGTATCTCTACATTGACATGAGTAGCTTGGGGACCATGACCCTTGTGT
  CTATACACACCACGNAGAAGTACATGGAGTTCTGCATCAGCAGCGATCTCACAGTCCACT
  GAGGACTCGTGGCATTCCATTACTCAAAGTGATCTGGAATACCATGACTGNGGACCCAGA
  ATGATTCCGGTATGGACTAAATGCTTAGACTTTACCAATC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_130846 unedited
  ANGAGCCTGGGGNAGGGTCACAGGGCTGCCACCCGGGATCTGTTCAGGAAACAGCTATGA
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGAGTTCTGGAGCAGAAG
  CCACCTTTATGCCCAATAATAGAGAGTAAATACATATATACCCAATGACAATCATTGTGC
  TCTGTAATTGTTTGATAGGAGGGACTATAAATACACATTTAATAGGTAATATTATCAAGA
  CACATTTCCATATAAAATAGTTACTGTTTTTGATTTTTGTTTTTCAAAAACAAAGACTTC
  TCTGTTAAAAATCCATTATCAATCACTTGCAACTTTAGCAGCAAGATTCTGGTAACTGAG
  AAAGGTAATAGCACTTCAAAACAGGAACAGTTTAACAGCTGACAGTCCATTCACAAGACA
  GATTTTGCAAACATTAAAGCATCTAACACATAATACGAATGTCTTCAGCAGCTCATCCAG
  TCATCACCTGATGACATTTATTACTGAATATTACATACATACATTCTGTGTGGCAGATAG
  AGTCAGTACAGACAAAACAAAATCTGCCTTAGGCTGTGTGATAAACCTATCATACCTCCA
  TCATCAAAAAACCTTCAGAATAATTTGGGGGATGCTTACAAATGCATTCATATACACAAG
  GAGCTGGAAATCTTAAATATGTTGCCCAGTCTTCCACAATCCATGCCATACATGGGCTTC
  AGAGCTTCTCCTTCCTTCCATTGCAGGAAGCTCCTTCTAGAAGCCTTGGGTGGGTAATTT
  GATTAATCACCCCAAGAGATTGATGGTCTGACAAGTCTTCAATGACTCACTGGACAGTCT
  CTGCTGAAAGTCTGCTCTCATACAGGCACAGAGCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130846
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_130846.1, NP_570897.1
• RefSeq Size: 2733 bp
• RefSeq ORF: 1239 bp
• Locus ID: 5801
• Cytogenetics: 12q15
• Domains: Y_phosphatase
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: MAPK signaling pathway
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2, also referred to as isoform gamma) has a distinct N-terminus and is shorter than isoform 1.