PCPTP1 (PTPRR) (NM_130846) Human Untagged Clone

CAT#: SC128013

PTPRR (untagged)-Human protein tyrosine phosphatase, receptor type, R (PTPRR), transcript variant 2


  "NM_130846" in other vectors (4)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PTPRR
Synonyms EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC128013 sequence for NM_130846 edited (data generated by NextGen Sequencing)
ATGATTCTTTACAGATTAAAAGAAAGATTTCAGCTTTCCTTAAGACAAGACAAAGAGAAA
AACCAGGAGATCCACCTATCGCCCATCACATTACAGCCAGCACTGTCCGAGGCAAAGACA
GTCCACAGCATGGTCCAACCTGAGCAGGCCCCAAAGGTACTGAATGTTGTCGTGGACCCT
CAAGGCCGAGGTGCTCCTGAGATCAGAGCTACCACCGCTACCTCTGTTTGCCCTTCTCCT
TTCAAAATGAAGCCCATAGGACTTCAAGAGAGAAGAGGGTCCAACGTATCTCTTACATTG
GACATGAGTAGCTTGGGGAACATTGAACCCTTTGTGTCTATACCAACACCACGGGAGAAG
GTAGCAATGGAGTATCTGCAGTCAGCCAGCCGAATTCTCACAAGGTCTCAGCTGAGGGAC
GTCGTGGCAAGTTCACATTTACTCCAAAGTGAATTCATGGAAATACCAATGAACTTTGTG
GATCCCAAAGAAATTGATATTCCGCGTCATGGAACTAAAAATCGCTATAAGACCATTTTA
CCAAATCCCCTCAGCAGAGTGTGTTTAAGACCAAAAAATGTAACCGATTCATTGAGCACC
TACATTAATGCTAATTATATTAGGGGCTACAGTGGCAAGGAGAAAGCCTTCATTGCCACG
CAGGGCCCCATGATCAACACCGTGGATGATTTCTGGCAGATGGTTTGGCAGGAAGACAGC
CCTGTGATTGTTATGATCACAAAACTCAAAGAAAAAAATGAGAAATGTGTGCTATACTGG
CCGGAAAAGAGAGGGATATATGGAAAAGTTGAGGTTCTGGTTATCAGTGTAAATGAATGT
GATAACTACACCATTCGAAACCTTGTCTTAAAGCAAGGAAGCCACACCCAACATGTGAAG
CATTACTGGTACACCTCATGGCCTGATCACAAGACTCCAGACAGTGCCCAGCCCCTCCTA
CAGCTCATGCTGGATGTAGAAGAAGACAGACTTGCTTCCCAGGGCCGAGGGCCTGTGGTT
GTCCACTGCAGTGCAGGAATAGGTAGAACAGGGTGTTTTATTGCTACATCCATTGGCTGT
CAACAGCTGAAAGAAGAAGGAGTTGTGGATGCACTAAGCATTGTCTGCCAGCTTCGTATG
GATAGAGGTGGAATGGTGCAAACCAGTGAGCAGTATGAATTTGTGCACCATGCTCTGTGC
CTGTATGAGAGCAGACTTTCAGCAGAGACTGTCCAGTGA

Clone variation with respect to NM_130846.2
206 a=>g
>OriGene 5' read for NM_130846 unedited
CGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGAACTCTCTTACCTATGAACC
AGGTAGTTTCCAAGAGAGACGCTGAGGGATGTTTAGAAAGCCTGGGACCTGCAGATGCCA
TGTCAGGCACGCTTGCTCCTGCATAGGAGACTAAATAATCTCGATATATAAGGATGGCAG
TCTGTTGTCTTAGATCAGTTTGAGAAGCAGCTCTGGCAGCGGGGGGTGTAGGTGTGTTGC
ACTACACTGAATGGAATAAGGCTAAAAATATGTTTAGTGTCTGATAAGAACGCCAGTTTT
CTCAAGCTCTCATTTAACGTCGGACTTTCTGTTTTGCTTTTAAAGAAAAATGTTTTACAA
GGGCAGCATGAAGCGGACAAAATCTGGAGCAAAGAAGGATTTTATGCTGTTGTCATTTTT
CTCAGCATCTTTGTTATTATAGTAACGTGTTTGATGATTCTTTACAGATTAAAAGAAAGA
TTTCAGCTTTCCTTAAGACAAGACAAAGAGAAAAACCAGGAGATCCACCTATCGCCCATC
ACATTACAGCCAGCACTGTCCGAGGCAAAGACAGTCCACAGCATGGTCCAACCTGAGCAG
GCCCCANAGGTACTGAATGTTGTCGTGGACCCTCAANGCCGAGTGCTCCTGAGATCAGAG
CTACCACCGCTACCTCTGTTTGCCCTTCTCCTTTCAAATGAAGCCCATNNAGACTCAGAG
AGAGAGGGTCCACGTATCTCTACATTGACATGAGTAGCTTGGGGACCATGACCCTTGTGT
CTATACACACCACGNAGAAGTACATGGAGTTCTGCATCAGCAGCGATCTCACAGTCCACT
GAGGACTCGTGGCATTCCATTACTCAAAGTGATCTGGAATACCATGACTGNGGACCCAGA
ATGATTCCGGTATGGACTAAATGCTTAGACTTTACCAATC
>OriGene 3' read for NM_130846 unedited
ANGAGCCTGGGGNAGGGTCACAGGGCTGCCACCCGGGATCTGTTCAGGAAACAGCTATGA
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGAGTTCTGGAGCAGAAG
CCACCTTTATGCCCAATAATAGAGAGTAAATACATATATACCCAATGACAATCATTGTGC
TCTGTAATTGTTTGATAGGAGGGACTATAAATACACATTTAATAGGTAATATTATCAAGA
CACATTTCCATATAAAATAGTTACTGTTTTTGATTTTTGTTTTTCAAAAACAAAGACTTC
TCTGTTAAAAATCCATTATCAATCACTTGCAACTTTAGCAGCAAGATTCTGGTAACTGAG
AAAGGTAATAGCACTTCAAAACAGGAACAGTTTAACAGCTGACAGTCCATTCACAAGACA
GATTTTGCAAACATTAAAGCATCTAACACATAATACGAATGTCTTCAGCAGCTCATCCAG
TCATCACCTGATGACATTTATTACTGAATATTACATACATACATTCTGTGTGGCAGATAG
AGTCAGTACAGACAAAACAAAATCTGCCTTAGGCTGTGTGATAAACCTATCATACCTCCA
TCATCAAAAAACCTTCAGAATAATTTGGGGGATGCTTACAAATGCATTCATATACACAAG
GAGCTGGAAATCTTAAATATGTTGCCCAGTCTTCCACAATCCATGCCATACATGGGCTTC
AGAGCTTCTCCTTCCTTCCATTGCAGGAAGCTCCTTCTAGAAGCCTTGGGTGGGTAATTT
GATTAATCACCCCAAGAGATTGATGGTCTGACAAGTCTTCAATGACTCACTGGACAGTCT
CTGCTGAAAGTCTGCTCTCATACAGGCACAGAGCA
Restriction Sites NotI-NotI     
ACCN NM_130846
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_130846.1, NP_570897.1
RefSeq Size 2733 bp
RefSeq ORF 1239 bp
Locus ID 5801
Cytogenetics 12q15
Domains Y_phosphatase
Protein Families Druggable Genome, Phosphatase, Transmembrane
Protein Pathways MAPK signaling pathway
Gene Summary 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]'
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2, also referred to as isoform gamma) has a distinct N-terminus and is shorter than isoform 1.

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