CDC14B (NM_003671) Human Untagged Clone

CAT#: SC128030

CDC14B (untagged)-Human CDC14 cell division cycle 14 homolog B (S. cerevisiae) (CDC14B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC14B
• Synonyms: Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003671, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCGGAAAAGCGAGCGGCGGTCGAGCTGGGCCGCCGCGCCCCCCTGCTCGCGGCGCTGCTCGTCGA
  CCTCGCCGGGTGTGAAGAAGATCCGCAGCTCCACGCAGCAAGACCCGCGCCGCCGGGACCCCCAGGACGA
  CGTGTACCTGGACATCACCGATCGCCTTTGTTTTGCCATTCTCTACAGCAGACCAAAGAGTGCATCAAAT
  GTACATTATTTCAGCATAGATAATGAACTTGAATATGAGAACTTCTACGCAGATTTTGGACCACTCAATC
  TGGCAATGGTTTACAGATATTGTTGCAAGATCAATAAGAAATTAAAGTCCATTACAATGTTAAGGAAGAA
  AATTGTTCATTTTACTGGCTCTGATCAGAGAAAACAAGCAAATGCTGCCTTCCTTGTTGGATGCTACATG
  GTTATATATTTGGGGAGAACCCCAGAAGAAGCATATAGAATATTAATCTTTGGAGAGACATCCTATATTC
  CTTTCAGAGATGCTGCCTATGGAAGTTGCAATTTCTACATTACACTTCTTGACTGTTTTCATGCAGTAAA
  GAAGGCAATGCAGTATGGCTTCCTTAATTTCAACTCATTTAACCTTGATGAATATGAACACTATGAAAAA
  GCAGAAAATGGAGATTTAAATTGGATAATACCAGACCGATTTATTGCCTTCTGTGGACCTCATTCAAGAG
  CCAGACTTGAAAGTGGTTACCACCAACATTCTCCTGAGACTTATATTCAATATTTTAAGAATCACAATGT
  TACTACCATTATTCGTCTGAATAAAAGGATGTATGATGCCAAACGCTTTACGGATGCTGGCTTCGATCAC
  CATGATCTTTTCTTTGCGGATGGCAGCACCCCTACTGATGCCATTGTCAAAGAATTCCTAGATATCTGTG
  AAAATGCTGAGGGTGCCATTGCAGTACATTGCAAAGCTGGCCTTGGTCGCACGGGCACTCTGATAGCCTG
  CTACATCATGAAGCATTACAGGATGACAGCAGCCGAGACCATTGCGTGGGTCAGGATCTGCAGACCTGGC
  TCGGTGATTGGGCCTCAGCAGCAGTTTTTGGTGATGAAGCAAACCAACCTCTGGCTGGAAGGGGACTATT
  TTCGTCAGAAGTTAAAGGGGCAGGAGAATGGACAACACAGAGCAGCCTTCTCCAAACTTCTCTCTGGCGT
  TGATGACATTTCCATAAATGGGGTCGAGAATCAAGATCAGCAAGAACCCGAACCGTACAGTGATGATGAC
  GAAATCAATGGAGTGACACAAGGTGATAGACTTCGGGCCTTGAAAAGCAGAAGACAATCCAAAACAAACG
  CTATTCCTCTCACTCTCTCCATTTCAAGGACTAAAACAGTCTTGCGTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003671 unedited
  GCCATGGTCGTGGCCCCCTGACGGGCCGCGGCCGCCTCCATGAAGCGGAAAAGCGAGCGG
  CGGTCGAGCTGGGCCGCCGCGCCCCCCTGCTCGCGGCGCTGCTCGTCGACCTCGCCGGGT
  GTGAAGAAGATCCGCAGCTCCACGCAGCAAGACCCGCGCCGCCGGGACCCCCAGGACGAC
  GTGTACCTGGACATCACCGATCGCCTTTGTTTTGCCATTCTCTACAGCAGACCAAAGAGT
  GCATCAAATGTACATTATTTCAGCATAGATAATGAACTTGAATATGAGAACTTCTACGCA
  GATTTTGGACCCCTCAATCTGGCAATGGGTTACAGATATTGGTGCANGATCAATCAAGAA
  TTAAAGTCCATTACAATGTTAAGGAAGAAAATCGTTCATTTTACTGGCTCTGATCAGAGA
  AAACAAGCAAATGCTGCCTTTCCTTGTTGGATGCTCCATGGGTATATATTTTGGGGGGAA
  CCCCCTGAAGAAGCCTCTTCAATATTAACTCTTTGGAGAGACCTTCCTTATTTCCTTTCC
  AGAGATGCCTCCCTTTGGTATGTTGCTTTTCTCCTCTTACACTTCTTTGCTGTCTCTCTT
  GCCCCCCACCAGGGCCTGCCTCCTTGGGTTTTCTGTTTTTCTGTTCTCTTTTTTCTCTCC
  TTTCTCTTTTCTTCCTTGTCGCTCTTTCCTCACCTTGCTCTTCTCTTCTGTGGCTCGTCT
  CCTCTCCGCCCTGCCTCTGCCTCTGTACCNGTCTCCTCGCCTCCCCCCTCCTCCGACTTC
  GTTCTCTCCTTCCTCGCCTCGCCCTCTTCTCCTCTTCCTCCCCGATCTTACTTATTATCG
  CTTTTCCTCGCTCTTCCACTTCTAATATAACTATAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_003671 unedited
  TTACATGATTGTAATTATACAACTTTCCACTATTCGATATTTTGTATAAAACCAGTTACA
  ACCCACAAGATTTTCAAATGTGACAATATGTATCAAACTACATACATATGCAAAGTTTAC
  ACGCCATTAGGAAGCTTTATCTTAAAAATACCTTCAGGAAAATAAACATTCATTCAACCA
  GTTCTCTTGGCTTTAAAAAATATGATTAGAAATATACGCTGTAAAAAAAAATCAAGACAA
  TGATTGATCAATACTGATCAGTTACATTTTAAAACTTTTAATAATCTGTACATGAGTGCA
  GGTTANATAAAAGTCTGCACATTATTAATAGAAAACTGCAGTACTATCATCGGATGAACA
  TGTCTGCTGACAACCCTACCAGGTAATTCAGGAGGTAATTTCCTCCCCAGTTAGGTGACA
  CGTCCAGTGTTTAACCACATCTGGCGTCCTGCGCCCCTTCCGCCTTTCCCACCCCGTTAC
  CGTGTGTCATGCGTCGCCTCCCCTCCCCCATTGACGCGCTCTGCTTCTCATGCATCCTCT
  GATTCCTGACCCCACTCCGCCCCGCGCTTCTCCCCTCCTTGCCTATCTCCTTCTTCCTCC
  TCGGCCCTACGCCTTCCCTTCTCCCTCAGCCCCCCCCGCCTGCTCTGTTTTTTTTCCCCC
  CGTGTACCATGCTCCTCCCCCCCCGCCTCCCCCCCTCACATATCCGCCTCTTCTCATCCC
  CCTTTCCTTTCCCTCCCCTCGCCCTCCACTTCCCCCCCCCCCCCCCCTTCTCCCCTCCCC
  CCCCCCCCGCGCCACTCTTTTCGCTCGCGCTCACGCCCCCGCCCCTCCCTCTCCGCGTTC
  TTCGCCACGTTTCTTCTCCTTTCCCCCCCCTCCGCTCCTTATTCTTCTTTCCTTTTTTTT
  CCCTTTCTTTTTCTTTTCCCCATTCCCGTCCCTTTTTCTCCTCTCCCCCCTCCGGGCCGG
  TTCTCCCTCTTCTTCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003671
• ORF Size: 5472 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003671.2, NP_003662.1
• RefSeq Size: 5472
• RefSeq ORF: 5472
• Locus ID: 8555
• Domains: Y_phosphatase, DSPc, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Cell cycle
• Gene Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) lacks an alternate in-frame exon, compared to variant 2, resulting in a shorter protein (isoform 1) that lacks an internal segment in the C-terminal region, compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.