LGALS3BP (NM_005567) Human Untagged Clone

CAT#: SC128088

LGALS3BP (untagged)-Human lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LGALS3BP
• Synonyms: 90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128088 sequence for NM_005567 edited (data generated by NextGen Sequencing)
  ATGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAAC
  GATGGTGACATGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTC
  TACAGAGGCCAGTGGGGCACTGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTC
  GTCTGCCGGGCCCTGGGCTTCGAGAACGCCACCCAGGCTCTGGGCAGAGCTGCCTTCGGG
  CAAGGATCAGGCCCCATCATGCTGGAYGAGGTCCAGTGCACGGGAACCGAGGCCTCACTG
  GCCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAGAGACGCTGGT
  GTGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCG
  GAGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAAT
  GTGCAGGGCGAGGACGCCCTGGGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTG
  GAGGCCCAGGCCCTGTGGAAGGAGCCGGGCAGCAATGTCACCATGAGTGTGGATGCTGAG
  TGTGTGCCCATGGTCAGGGACCTTCTCAGGTACTTCTACTCCCGAAGGATTGACATCACC
  CTGTCGTCAGTCAAGTGCTTCCACAAGCTGGCCTCTGCCTATGGGGCCAGGCAGCTGCAG
  GGCTACTGCGCAAGCCTCTTTGCCATCCTCCTCCCCCAGGACCCCTCGTTCCAGATGCCC
  CTGGACCTGTATGCCTATGCAGTGGCCACAGGGGACGCCCTGCTGGAGAAGCTCTGCCTA
  CAGTTCCTGGCCTGGAACTTCGAGGCCTTGACGCAGGCCGAGGCCTGGCCCAGTGTCCCC
  ACAGACCTGCTCCAACTGCTGCTGCCCAGGAGCGACCTGGCGGTGCCCAGCGAGCTGGCC
  CTACTGAAGGCCGTGGACACCTGGAGCTGGGGGGAGCGTGCCTCCCATGAGGAGGTGGAG
  GGCTTGGTGGAGAAGATCCGCTTCCCCATGATGCTCCCTGAGGAGCTCTTTGAGCTGCAG
  TTCAACCTGTCCCTGTACTGGAGCCACGAGGCCCTGTTCCAGAAGAAGACTCTGCAGGCC
  CTGGAATTCCACACTGTGCCCTTCCAGTTGCTGGCCCGGTACAAAGGCCTGAACCTCACC
  GAGGATACCTACAAGCCCCGGATTTACACCTCGCCCACCTGGAGTGCCTTTGTGACAGAC
  AGTTCCTGGAGTGCACGGAAGTCACAACTGGTCTATCAGTCCAGACGGGGGCCTTTGGTC
  AAATATTCTTCTGATTACTTCCAAGCCCCCTCTGACTACAGATACTACCCCTACCAGTCC
  TTCCAGACTCCACAACACCCCAGCTTCCTCTTCCAGGACAAGAGGGTGTCCTGGTCCCTG
  GTCTACCTCCCCACCATCCAGAGCTGCTGGAACTACGGCTTCTCCTGCTCCTCGGACGAG
  CTCCCTGTCCTGGGCCTCACCAAGTCTGGCGGCTCAGATCGCACCATTGCCTACGAAAAC
  AAAGCCCTGATGCTCTGCGAAGGGCTCTTCGTGGCAGACGTCACCGATTTCGAGGGCTGG
  AAGGCTGCGATTCCCAGTGCCCTGGACACCAACAGCTCGAAGAGCACCTCCTCCTTCCCC
  TGCCCGGCAGGGCACTTCAACGGCTTCCGCACGGTCATCCGCCCCTTCTACCTGACCAAC
  TCCTCAGGTGTGGACTAG
  
  Clone variation with respect to NM_005567.3
  267 t=>y
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005567 unedited
  NTGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGGCTCCATAC
  TGGGAGAGGCTTCTGGGTCAAAGGACCAGTCTGCAGAGGGATCCTGTGGCTGGAAGCGAG
  GAGGCTCCACACGGCCGTTGCAGCTACCGCAGCCAGGATCTGGGCATCCAGGCACGGCCA
  TGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAACG
  ATGGTGACATGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTCT
  ACAGAGGCCAGTGGGGCACTGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTCG
  TCTGCCGGGCCCTGGGCTTCGAGAACGCCACCCAGGCTCTGGGCAGAGCTGCCTTCGGGC
  AAGGATCAGGCCCCATCATGCTGGATGAGGTCCAGTGCACGGGAACCGAGGCCTCACTGG
  CCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAGAGACGCTGGTG
  TGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCGG
  AGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAATG
  TGCAGGGCGAGGACGCCCTGNGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTGG
  AGGCCCAGGCCCTGTGGAAGGAGCCGGGCAGCAATGTCACCATGAGTGTGGNATGCTGAG
  TGTGTGCCCATGGTCAGGNACCTTCTCANGTACTTCTACTNCCGAAGGATTGACATCACC
  CCTGTCGTCAGTCAAGTGCTTCCACAAGCTGGNCTCTGCCTATGGGGCCAGGCAGCTGCA
  GGGCTACTGCGCAAGCCTCTTGCCATNCTNCTNCNCAGNACCCNTCGNTNCAGATGCCCT
  G
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_005567 unedited
  NNTTTGCTATGGACGCGGCCGCAATCTATGATCGAGTTTTTTTTTTTTTTTTTTTTAGGA
  ACCTCAATGTAATTTTAATGACCTCAGACCAGTGACAAGGGCAGACTGACCAGGGGCTGT
  GGGGGGATCCCAGAGCAACCTCGAGGGCGTCCTGGTGCTTACCACCTGGAAACTGGTGAG
  GTGGTGGGAGAACTCCTGGTGGACCCTAGTGGAAGCCTTCCAGTAATTTCTTGAAGCTGA
  GCGCTCAGGTGAGTAGGGCGACATCTGGTGGCCGGTTGTTGAAGGTCATTGCAGAGAGGA
  AGGAAGCCGAGGAGGGGAGCCTGCAGTGAGGGCGTCCTGGGGTTCTCCGGTTCTCACCAC
  CCTTGGGCCACGCCGTCTAGTCCACACCTGAGGAGTTGGTCAGGTAGAAGGGGCGGATGA
  CCGTGCGGAAGCCGTTGAAGTGCCCTGCCGGGCAGGGGAAGGAGGAGGTGCTCTTCGAGC
  TGTTGGTGTCCAGGGCACTGGGAATCGCAGCCTTCCAGCCCTCGAAATCGGTGACGTCTG
  CCACGAAGAGCCCTTCGCAGAGCATCAGGGCTTTGTTTTCGTAGGCAATGGTGCGATCTG
  AGCCGCCAGACTTGGTGAGGCCCAGGACAGGGAGCTCGTCCGAGGAGCAGGAGAAGCCGT
  AGTTCCAGCAGCTCTGGATGGTGGGGGAGGTAGACCAGGGACCAGGACACCCTCTTGTCC
  TGGAAAAGGAGCTGGGGTGTTGTGGAGTCTGGAAGGACTGGTAGGGGTAGTATCTGTAGT
  CAGAAGGGGCTTGGAAGTTATCAGAAGATATTTGACCAAAGGCCCCCGTCTGGACTGATA
  AACCAGTTGTGACTTCCGTGCACTCCAGGAACTGTCTGTCACAAAGCACTTCCAGTGGGC
  CAGGTGTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005567
• Insert Size: 2500 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005567.2, NP_005558.1
• RefSeq Size: 2254 bp
• RefSeq ORF: 1758 bp
• Locus ID: 3959
• Cytogenetics: 17q25.3
• Domains: SR
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: 'The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]'