LGALS3BP (NM_005567) Human Untagged Clone

CAT#: SC128088

LGALS3BP (untagged)-Human lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP)


  "NM_005567" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol LGALS3BP
Synonyms 90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC128088 sequence for NM_005567 edited (data generated by NextGen Sequencing)
ATGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAAC
GATGGTGACATGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTC
TACAGAGGCCAGTGGGGCACTGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTC
GTCTGCCGGGCCCTGGGCTTCGAGAACGCCACCCAGGCTCTGGGCAGAGCTGCCTTCGGG
CAAGGATCAGGCCCCATCATGCTGGAYGAGGTCCAGTGCACGGGAACCGAGGCCTCACTG
GCCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAGAGACGCTGGT
GTGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCG
GAGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAAT
GTGCAGGGCGAGGACGCCCTGGGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTG
GAGGCCCAGGCCCTGTGGAAGGAGCCGGGCAGCAATGTCACCATGAGTGTGGATGCTGAG
TGTGTGCCCATGGTCAGGGACCTTCTCAGGTACTTCTACTCCCGAAGGATTGACATCACC
CTGTCGTCAGTCAAGTGCTTCCACAAGCTGGCCTCTGCCTATGGGGCCAGGCAGCTGCAG
GGCTACTGCGCAAGCCTCTTTGCCATCCTCCTCCCCCAGGACCCCTCGTTCCAGATGCCC
CTGGACCTGTATGCCTATGCAGTGGCCACAGGGGACGCCCTGCTGGAGAAGCTCTGCCTA
CAGTTCCTGGCCTGGAACTTCGAGGCCTTGACGCAGGCCGAGGCCTGGCCCAGTGTCCCC
ACAGACCTGCTCCAACTGCTGCTGCCCAGGAGCGACCTGGCGGTGCCCAGCGAGCTGGCC
CTACTGAAGGCCGTGGACACCTGGAGCTGGGGGGAGCGTGCCTCCCATGAGGAGGTGGAG
GGCTTGGTGGAGAAGATCCGCTTCCCCATGATGCTCCCTGAGGAGCTCTTTGAGCTGCAG
TTCAACCTGTCCCTGTACTGGAGCCACGAGGCCCTGTTCCAGAAGAAGACTCTGCAGGCC
CTGGAATTCCACACTGTGCCCTTCCAGTTGCTGGCCCGGTACAAAGGCCTGAACCTCACC
GAGGATACCTACAAGCCCCGGATTTACACCTCGCCCACCTGGAGTGCCTTTGTGACAGAC
AGTTCCTGGAGTGCACGGAAGTCACAACTGGTCTATCAGTCCAGACGGGGGCCTTTGGTC
AAATATTCTTCTGATTACTTCCAAGCCCCCTCTGACTACAGATACTACCCCTACCAGTCC
TTCCAGACTCCACAACACCCCAGCTTCCTCTTCCAGGACAAGAGGGTGTCCTGGTCCCTG
GTCTACCTCCCCACCATCCAGAGCTGCTGGAACTACGGCTTCTCCTGCTCCTCGGACGAG
CTCCCTGTCCTGGGCCTCACCAAGTCTGGCGGCTCAGATCGCACCATTGCCTACGAAAAC
AAAGCCCTGATGCTCTGCGAAGGGCTCTTCGTGGCAGACGTCACCGATTTCGAGGGCTGG
AAGGCTGCGATTCCCAGTGCCCTGGACACCAACAGCTCGAAGAGCACCTCCTCCTTCCCC
TGCCCGGCAGGGCACTTCAACGGCTTCCGCACGGTCATCCGCCCCTTCTACCTGACCAAC
TCCTCAGGTGTGGACTAG

Clone variation with respect to NM_005567.3
267 t=>y
>OriGene 5' read for NM_005567 unedited
NTGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGGCTCCATAC
TGGGAGAGGCTTCTGGGTCAAAGGACCAGTCTGCAGAGGGATCCTGTGGCTGGAAGCGAG
GAGGCTCCACACGGCCGTTGCAGCTACCGCAGCCAGGATCTGGGCATCCAGGCACGGCCA
TGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAACG
ATGGTGACATGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTCT
ACAGAGGCCAGTGGGGCACTGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTCG
TCTGCCGGGCCCTGGGCTTCGAGAACGCCACCCAGGCTCTGGGCAGAGCTGCCTTCGGGC
AAGGATCAGGCCCCATCATGCTGGATGAGGTCCAGTGCACGGGAACCGAGGCCTCACTGG
CCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAGAGACGCTGGTG
TGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCGG
AGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAATG
TGCAGGGCGAGGACGCCCTGNGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTGG
AGGCCCAGGCCCTGTGGAAGGAGCCGGGCAGCAATGTCACCATGAGTGTGGNATGCTGAG
TGTGTGCCCATGGTCAGGNACCTTCTCANGTACTTCTACTNCCGAAGGATTGACATCACC
CCTGTCGTCAGTCAAGTGCTTCCACAAGCTGGNCTCTGCCTATGGGGCCAGGCAGCTGCA
GGGCTACTGCGCAAGCCTCTTGCCATNCTNCTNCNCAGNACCCNTCGNTNCAGATGCCCT
G
>OriGene 3' genomic read for NM_005567 unedited
NNTTTGCTATGGACGCGGCCGCAATCTATGATCGAGTTTTTTTTTTTTTTTTTTTTAGGA
ACCTCAATGTAATTTTAATGACCTCAGACCAGTGACAAGGGCAGACTGACCAGGGGCTGT
GGGGGGATCCCAGAGCAACCTCGAGGGCGTCCTGGTGCTTACCACCTGGAAACTGGTGAG
GTGGTGGGAGAACTCCTGGTGGACCCTAGTGGAAGCCTTCCAGTAATTTCTTGAAGCTGA
GCGCTCAGGTGAGTAGGGCGACATCTGGTGGCCGGTTGTTGAAGGTCATTGCAGAGAGGA
AGGAAGCCGAGGAGGGGAGCCTGCAGTGAGGGCGTCCTGGGGTTCTCCGGTTCTCACCAC
CCTTGGGCCACGCCGTCTAGTCCACACCTGAGGAGTTGGTCAGGTAGAAGGGGCGGATGA
CCGTGCGGAAGCCGTTGAAGTGCCCTGCCGGGCAGGGGAAGGAGGAGGTGCTCTTCGAGC
TGTTGGTGTCCAGGGCACTGGGAATCGCAGCCTTCCAGCCCTCGAAATCGGTGACGTCTG
CCACGAAGAGCCCTTCGCAGAGCATCAGGGCTTTGTTTTCGTAGGCAATGGTGCGATCTG
AGCCGCCAGACTTGGTGAGGCCCAGGACAGGGAGCTCGTCCGAGGAGCAGGAGAAGCCGT
AGTTCCAGCAGCTCTGGATGGTGGGGGAGGTAGACCAGGGACCAGGACACCCTCTTGTCC
TGGAAAAGGAGCTGGGGTGTTGTGGAGTCTGGAAGGACTGGTAGGGGTAGTATCTGTAGT
CAGAAGGGGCTTGGAAGTTATCAGAAGATATTTGACCAAAGGCCCCCGTCTGGACTGATA
AACCAGTTGTGACTTCCGTGCACTCCAGGAACTGTCTGTCACAAAGCACTTCCAGTGGGC
CAGGTGTA
Restriction Sites NotI-NotI     
ACCN NM_005567
Insert Size 2500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005567.2, NP_005558.1
RefSeq Size 2254 bp
RefSeq ORF 1758 bp
Locus ID 3959
Cytogenetics 17q25.3
Domains SR
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]'

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