GLEPP1 (PTPRO) (NM_030667) Human Untagged Clone

CAT#: SC128123

PTPRO (untagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRO
• Synonyms: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_030667, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGCACCTGCCCACGGGGATACACGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGT
  TCAAGAATGCTACAGCTTTCCATGTAACTGTCCAAGATGATAATAACATCGTTGTCTCATTAGAAGCTTC
  AGACGTCATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAAAAATTATTTCTTCGAA
  TTTGAGGAATTCAACAGCACTTTGCCTCCTCCTGTTATTTTCAAGGCCAGTTATCATGGCCTTTATTATA
  TAATCACTCTGGTAGTGGTAAATGGAAATGTGGTGACCAAGCCATCCAGATCAATCACTGTGTTAACAAA
  ACCTCTACCTGTAACCAGTGTTTCCATATATGACTATAAACCTTCTCCTGAAACAGGAGTCCTGTTTGAA
  ATACATTATCCAGAAAAATATAACGTTTTCACAAGAGTGAACATTAGCTACTGGGAAGGTAAAGACTTCC
  GGACAATGCTATATAAAGATTTCTTTAAGGGAAAAACAGTATTTAATCACTGGCTGCCAGGAATGTGTTA
  TAGTAATATCACCTTTCAGCTGGTATCTGAGGCAACTTTTAATAAAAGTACCCTTGTTGAGTACAGTGGT
  GTCAGTCACGAACCCAAACAGCACAGAACTGCCCCTTATCCACCTCAAAATATTTCCGTTCGTATCGTAA
  ACTTGAACAAAAACAACTGGGAAGAACAGAGTGGCAATTTCCCAGAAGAATCCTTCATGAGATCACAAGA
  TACAATAGGAAAAGAAAAACTCTTCCATTTTACAGAAGAAACCCCTGAAATTCCCTCGGGCAACATTTCT
  TCCGGTTGGCCTGATTTTAATAGCAGTGACTATGAAACTACGTCTCAGCCATATTGGTGGGACAGTGCAT
  CTGCAGCTCCTGAAAGTGAAGATGAATTTGTCAGCGTACTTCCCATGGAATACGAAAATAACAGTACACT
  CAGTGAGACAGAGAAGTCAACATCAGGCTCTTTCTCCTTTTTCCCTGTGCAAATGATATTGACCTGGTTA
  CCACCCAAACCACCCACTGCTTTTGATGGGTTCCATATCCATATTGAACGAGAAGAGAACTTTACTGAAT
  ATTTGATGGTGGATGAAGAAGCACATGAATTTGTTGCAGAACTGAAGGAACCTGGGAAATATAAGTTATC
  TGTGACAACCTTTAGTTCCTCAGGATCTTGTGAAACTCGAAAAAGTCAGTCAGCAAAATCACTCAGCTTT
  TATATCAGTCCTTCAGGAGAGTGGATTGAAGAACTGACCGAGAAGCCGCAGCACGTGAGTGTCCACGTTT
  TAAGCTCAACCACTGCCTTGATGTCCTGGACATCTTCCCAAGAGAACTACAACAGCACCATTGTGTCTGT
  GGTGTCGCTGACCTGCCAGAAACAAAAGGAGAGCCAGAGGCTTGAAAAGCAGTACTGCACTCAGGTGAAC
  TCAAGCAAACCTATTATTGAAAATCTGGTTCCTGGTGCCCAGTACCAGGTTGTAATATACCTAAGGAAAG
  GCCCTTTGATTGGACCACCTTCAGATCCTGTGACATTTGCTATTGTTCCCACAGGAATAAAGGATTTAAT
  GCTCTATCCTTTGGGTCCTACGGCCGTGGTTCTGAGCTGGACCAGACCTTATTTAGGCGTGTTCAGAAAA
  TACGTGGTTGAAATGTTTTATTTCAACCCTGCTACAATGACATCAGAGTGGACCACCTACTATGAAATAG
  CAGCAACTGTTTCCTTAACTGCATCCGTGAGAATAGCTAATCTGCTGCCAGCATGGTACTACAACTTCCG
  GGTTACCATGGTGACGTGGGGAGATCCAGAATTGAGCTGCTGTGACAGCTCTACCATCAGCTTCATAACA
  GCCCCAGTGGCTCCGGAAATCACTTCTGTGGAATATTTCAACAGTCTGTTATATATCAGTTGGACATATG
  GGGATGATACAACGGACTTGTCCCATTCTAGAATGCTTCACTGGATGGTGGTTGCAGAAGGAAAAAAGAA
  AATTAAAAAGAGTGTAACACGCAATGTCATGACTGCAATTCTCAGCTTGCCTCCAGGCGACATCTATAAC
  CTCTCAGTAACTGCTTGTACTGAAAGAGGAAGTAATACCTCCATGCTCCGCCTTGTCAAGCTAGAACCAG
  CTCCACCCAAATCACTCTTCGCAGTGAACAAAACCCAGACTTCAGTGACTTTGCTGTGGGTGGAAGAGGG
  AGTAGCTGATTTCTTTGAAGTTTTCTGTCAACAAGTTGGCTCCAGTCAGAAAACCAAACTTCAGGAACCA
  GTTGCTGTTTCTTCCCATGTCGTGACCATCTCCAGCCTTCTTCCTGCCACTGCCTACAATTGTAGTGTCA
  CCAGCTTTAGCCATGACAGCCCCAGTGTCCCTACGTTCATAGCCGTCTCAACAATGGTTACAGAGATGAA
  TCCCAATGTGGTAGTGATCTCCGTGCTGGCCATCCTTAGCACACTTTTAATTGGACTGTTGCTTGTTACC
  CTCATTATTCTTAGGAAAAAGCATCTGCAGATGGCTAGGGAGTGTGGAGCTGGTACATTTGTCAATTTTG
  CATCCTTAGAGAGGGATGGAAAGCTTCCATACAACTGGCGTAGGAGTATATTTGCTTTCTTAACCCTGCT
  ACCCTCATGTCTTTGGACTGATTATCTTTTGGCATTTTATATTAATCCTTGGAGTAAAAATGGTTTAAAG
  AAGAGGAAACTGACAAACCCGGTTCAACTGGATGACTTTGATGCCTATATTAAGGATATGGCCAAAGACT
  CTGACTATAAATTTTCTCTTCAGTTTGAGGAGTTGAAATTGATTGGACTGGATATCCCACACTTTGCTGC
  AGATCTTCCACTGAATCGATGTAAAAACCGTTACACAAACATCCTACCATATGACTTCAGCCGTGTGAGA
  TTAGTCTCCATGAATGAAGAGGAAGGTGCAGACTACATCAATGCCAACTATATTCCTGGATACAACTCAC
  CCCAGGAGTATATTGCCACCCAGGGGCCACTGCCTGAAACCAGAAATGACTTCTGGAAGATGGTCCTGCA
  ACAAAAGTCTCAGATTATTGTCATGCTCACTCAGTGTAATGAGAAAAGGAGGGTGAAATGTGACCATTAC
  TGGCCATTCACGGAAGAACCTATAGCCTATGGAGACATCACTGTGGAGATGATTTCAGAGGAAGAGCAGG
  ACGACTGGGCCTGTAGACACTTCCGGATCAACTATGCTGACGAGATGCAGGATGTGATGCATTTTAACTA
  CACTGCATGGCCTGATCATGGTGTGCCCACAGCAAATGCTGCAGAAAGTATCCTGCAGTTTGTACACATG
  GTCCGACAGCAAGCTACCAAGAGCAAAGGTCCCATGATCATTCACTGCAGTGCTGGCGTGGGACGGACAG
  GAACATTCATTGCCCTGGACAGGCTCTTGCAGCACATTCGGGATCATGAGTTTGTTGACATCTTAGGGCT
  GGTGTCAGAAATGAGGTCATACCGGATGTCTATGGTACAGACAGAGGAGCAGTACATTTTTATCCATCAG
  TGTGTGCAACTGATGTGGATGAAGAAGAAGCAGCAGTTCTGCATCAGTGATGTCATATACGAGAATGTTA
  GCAAGTCCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030667 unedited
  TGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCAGCAGCGCCTGGCAC
  GTTCTTGGAGGACCCCGGGCGCAGAGGAGGAAAGGGAGCAGGCGCAGGGGGACTGGAAAG
  GCAGCATGCGCTCGCCAGGAGCAACCTCGGCGCCCAGGGTCTGAGGCTGCAGCCCCAGTT
  CGCCATTGTGAGCCGCCGCCGGGGGAGTCCGCTAGCGCAGCCGTGCCCCCGAGTCCCCGT
  CCGCGCAGCGATGGGGCACCTGCCCACGGGGATACACGGCGCCCGCCGCCTCCTGCCTCT
  GCTCTGGCTCTTTGTGCTGTTCAAGAATGCTACAGCTTTCCATGTAACTGTCCAAGATGA
  TAATAACATCGTTGTCTCATTAGAAGCTTCAGACGTCATCAGTCCAGCATCTGTGTATGT
  TGTGAAGATAACTGGTGAATCCAAAAATTATTTCTTCGAATTTGAGGAATTCAACAGCAC
  TTTGCCTCCTCCTGTTATTTTCAAGGCCAGTTATCATGGCCTTTATTATATAATCACTCT
  GGTAGTGGTAAATGGAAATGTGGTGACCAAGCCATCCAGATCAATCACTGTGTTAACAAA
  ACCTCTACCTGTAACCAGTGTTTCCATATATGACTATAAACCTTCTCCTGAACAGGAGTC
  CTGTTTGAAATACATTATCCAGAAAAATATAACGTTTTCACAAGAGTGAACATTAGCTAC
  TGGGGAGGTAAAGACTTCCGGACAATGCTATATAAAGATTTCTTTAGGGAAAAACAGTAT
  TTAATCACTGGCTGCCAGGAATGTGNTATAGTAATATCACCTTTCAGCTGGTATCTGNAG
  GCACTTTAATAANAGTACCCTGNTGAGTACAGTGGTGTCAGTCACGACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_030667 unedited
  AACTTAGNNCACGCGGCCGCATNCTANGATCGAATTTTTTTTTTTTTTTTTTTTTANATG
  CCACAGGGAACAGCCAGCTTGTGTTTACTTTCAACTCAAAATGGTTTCTGTTGTATATCC
  ATGTCATCACCTCTTATTTATCAGGAAGTGACACAAAGTAACAGGCTTCACAATGCCATC
  AATGTCATTTTGACAGCATTCATGTCACAATACACAATCATGTGCTGTAATTATACAAAA
  TCCAAAGAATAAAATGTTACTAGTTACACTCGTTAAAATGAAACTGACAACCACAAGAAT
  AACAAAACTAAAAGAAATCTCTGTCATAATCCATAAAGACATTTGACAATATTACAAAAA
  AAAGTAGTCAAATAATTGTCCCAGCATGCTGCAGTTCATTGCCATAACTTCATAAATTCC
  CAGCTCTTTGGGGGAAAGAAAGTGCGTTTTCACAGCCTATATAGTTCTTAAAGAAATAGC
  TCTCACATGTATGCACGTCAACAGAACAAGGAATGCTTAGTCTAAGCACCACGATTGGTC
  AGACCGCAACAGAGTTCAAAGAGTCCAACTTGACACTTTTCTGCACCAGATGTGGTTTCT
  TGAAAAAGAACTTGGACAGCTACATTAGTCCAAAAGCGGCCGAGAAAGAACACCAACTGG
  TAATAAGGAATAAAACCCTCCCGAAACTAGCACACTCTGACACAATTTTTTTCTCCTACC
  CCAAGTTTGAAACCCTGAAATATAACCCTTGAAAACCTAAAGATTAAACCGCGTTGATTC
  TGGGGGATAAAAACCCCTCTCTTACCCTGAACACACCTCCCCCAATCCTATATCCGGGTA
  ACGCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030667
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_030667.1, NP_109592.1
• RefSeq Size: 5153 bp
• RefSeq ORF: 3651 bp
• Locus ID: 5800
• Cytogenetics: 12p13-p12
• Domains: Y_phosphatase, PTPc_motif, FN3
• Protein Families: Phosphatase, Transmembrane
• Gene Summary: 'This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.