CD32B (FCGR2B) (NM_004001) Human Untagged Clone

CAT#: SC128159

FCGR2B (untagged)-Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1


  "NM_004001" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol FCGR2B
Synonyms CD32; CD32B; FCG2; FCGR2; FCGR2C; FcRII-c; IGFR2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_004001, the custom clone sequence may differ by one or more nucleotides


ATGGGAATCCTGTCATTCTTACCTGTCCTTGCCACTGAGAGTGACTGGGCTGACTGCAAGTCCCCCCAGC
CTTGGGGTCATATGCTTCTGTGGACAGCTGTGCTATTCCTGGCTCCTGTTGCTGGGACACCTGCAGCTCC
CCCAAAGGCTGTGCTGAAACTCGAGCCCCAGTGGATCAACGTGCTCCAGGAGGACTCTGTGACTCTGACA
TGCCGGGGGACTCACAGCCCTGAGAGCGACTCCATTCAGTGGTTCCACAATGGGAATCTCATTCCCACCC
ACACGCAGCCCAGCTACAGGTTCAAGGCCAACAACAATGACAGCGGGGAGTACACGTGCCAGACTGGCCA
GACCAGCCTCAGCGACCCTGTGCATCTGACTGTGCTTTCTGAGTGGCTGGTGCTCCAGACCCCTCACCTG
GAGTTCCAGGAGGGAGAAACCATCGTGCTGAGGTGCCACAGCTGGAAGGACAAGCCTCTGGTCAAGGTCA
CATTCTTCCAGAATGGAAAATCCAAGAAATTTTCCCGTTCGGATCCCAACTTCTCCATCCCACAAGCAAA
CCACAGTCACAGTGGTGATTACCACTGCACAGGAAACATAGGCTACACGCTGTACTCATCCAAGCCTGTG
ACCATCACTGTCCAAGCTCCCAGCTCTTCACCGATGGGGATCATTGTGGCTGTGGTCACTGGGATTGCTG
TAGCGGCCATTGTTGCTGCTGTAGTGGCCTTGATCTACTGCAGGAAAAAGCGGATTTCAGCTCTCCCAGG
ATACCCTGAGTGCAGGGAAATGGGAGAGACCCTCCCTGAGAAACCAGCCAATCCCACTAATCCTGATGAG
GCTGACAAAGTTGGGGCTGAGAACACAATCACCTATTCACTTCTCATGCACCCGGATGCTCTGGAAGAGC
CTGATGACCAGAACCGTATTTAG


>OriGene 5' read for NM_004001 unedited
CAGTCAGATTTGTATACCATCACTATAGGCGGCCGCGATTCCCGGGATCTGCTGTGCTCT
GGGCGCCAGCTCGCTCCAGGAGTGATGGGAATCCTGTCATTCTTACCTGTCCTTGCCACT
GAGAGTGACTGGGCTGACTGCAAGTCCCCCCAGCCTTGGGGTCATATGCTTCTGTGGACA
GCTGTGCTATTCCTGGCTCCTGTTGCTGGGACACCTGCAGCTCCCCCAAGGCTGTGCTGA
AACTCGAGCCCCAGTGGATCAACGTGCTCCAGGAGGACTCTGTGACTCTGACATGCCGGG
GGACTCACAGCCCTGAGAGCGACTCCATTCAGTGGTTCCACAATGGGAATCTCATTCCCA
CCCACACGCAGCCCAGCTACAGGTTCAAGGCCAACAACAATGACAGCGGGGAGTACACGT
GCCAGACTGGCCAGACCAGCCTCAGCGACCCTGTGCATCTGACTGTGCTTTCTGAGTGGC
TGGTGCTCCAGACCCCTCACCTGGAGTTCCAGGAGGGAGAAACCATCGTGCTGAGGTGCC
ACAGCTGGAAAGACAAGCCTCTGGTCAAGGTCACATTCTTCCAGAATGGAAAATCCAAGA
AATTTTCCCGTTCGGATCCCAACTTCTCCATCCCACAAGCAAACCACAGTCACAGTGGTG
ATTACCACTGCACAGGTAACATATGCTACACGCTGGACTCATCCAAGCCTGGGACCATCA
CTGTCCAAGCTCCCCAGCTCTCACCGGTGGGGATCATTGGGGCTGTGGGCACTGGGATTG
CCTGTAACGCCAATGGTGCCGCCTGAATGGCCCTTGTCCACTGGAGGGAAAAACCGGATT
TAACTTCTCCAAGATAACCCGGGGTCCGGGACAAGGGAGAAACCCTTCCCGGGGAAACCA
GCCAATCCCACT
>OriGene 3' read for NM_004001 unedited
NNNNNAAAACTTTGGACGCGGNCCGCCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATTGGGTTTAAAAAGGGTTTA
TTAAAAAAGGAATATTTGGTCTTTTTTGAAAAATAAAGAAAATAAAAATCCTCCATAATT
TTTTCCCCCCGAAACAATCACTTTTAAGGGGCGGGGAGGGGGTAGTCTATTTTAACATTT
CTGAAATCATATAGATTTACCGGGTGGGTCTCACGGAACCGGGAACAAAAGCCTTTCCCA
AGGGGGTATTATCGGGTAAAAACAGGGGGTTGGTTAAATGGATTGGCTGGGGGGGTGGGG
AACGGAAAAACCTTGGTGTCAAAAAAAGCTGGAGCCCAAAAGGGGCCGTCGGGCATTTGG
GGCCCTATTGGCTGGGGGTTTCAGGGCAGGGGGCTTCAGGGCCCAGGGAGATGACTCTGG
GAAAAACCTTCTTTTTTGGAACTGGAGGATTTCCCTGGCCTCCCCAGGGGGATTTAGGGC
CGGGAATACCCGATCTTCCCCCTTTGGTTTTCTTCTCAAAACCCAATGGCAGACAAGGGG
GACTAAATACGGGTTTGGGCATTAGGGTTTTCCAAAGCATCCGGGGGCCTGAAAAGGGAA
TAGGGGATTGGGGTCTCAGCCCCCACTTTGGCAGCCTCATCAGGATTAAGGGGGATGGCT
GGGTTCTCAGGGAGGGGGCTCTCCATTTCCCCGGGCTAGGGGGACCCGGGGGAGCTGGAA
ACCCCCTTTTCCTGGGGAAGAACAAGGGCCCCTACGGGGGAACAAGGGGGCGCTTAAAGG
AAACCCGGGGGCCACCGGCCCCAAGGGCCCCCCTCGG
Restriction Sites Please inquire     
ACCN NM_004001
Insert Size 1600 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004001.3, NP_003992.3
RefSeq Size 1633 bp
RefSeq ORF 933 bp
Locus ID 2213
Cytogenetics 1q23.3
Domains ig, IGc2, IG
Protein Families ES Cell Differentiation/IPS, Transmembrane
Protein Pathways B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus
Gene Summary 'The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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